Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Scott W. McPherson"'
Autor:
Scott W. McPherson, Neal D. Heuss, Md. Abedin, Heidi Roehrich, Mark J. Pierson, Dale S. Gregerson
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background Characterizing immune cells and conditions that govern their recruitment and function in autoimmune diseases of the nervous system or in neurodegenerative processes is an area of active investigation. We sought to analyze the orig
Externí odkaz:
https://doaj.org/article/2a641efde8df410c8185e91b947ffbb4
Autor:
Scott W. McPherson, Neal D. Heuss, Ute Lehmann, Heidi Roehrich, Md. Abedin, Dale S. Gregerson
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-19 (2019)
Abstract Background Microglia are essential to the development of the CNS and its homeostasis. Our prior findings suggested a niche model to describe the behaviors of retinal microglia. Here, we ask whether new myeloid cells recruited to the retina a
Externí odkaz:
https://doaj.org/article/1bee8f55825a48459ffedaf09909018f
Autor:
Neal D. Heuss, Mark J. Pierson, Heidi Roehrich, Scott W. McPherson, Andrea L. Gram, Ling Li, Dale S. Gregerson
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-19 (2018)
Abstract Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFPhi retinal myeloid cells to the dying retinal ganglion cells and their axons. Howev
Externí odkaz:
https://doaj.org/article/604f904262024e8fb733d4220c4a0a13
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 1, Pp 177-184 (2010)
The presence and activity of dendritic cells (DC) in retina is controversial, as these cells are difficult to identify in retina due to limited markers and sparse numbers. Transgenic mice that express green fluorescent protein (GFP) on the CD11c prom
Externí odkaz:
https://doaj.org/article/18e76b34990540b0afc85e685f2ad45b
Publikováno v:
American Journal of Ophthalmology, 216, pp. A5-a6
American Journal of Ophthalmology
American Journal of Ophthalmology, 216, A5-a6
American Journal of Ophthalmology
American Journal of Ophthalmology, 216, A5-a6
Contains fulltext : 225971.pdf (Publisher’s version ) (Closed access)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc3babc5a658eebd24956388130e668
https://hdl.handle.net/2066/225971
https://hdl.handle.net/2066/225971
Autor:
Ling Li, Scott W. McPherson, Andrea L. Gram, Neal D. Heuss, Mark Pierson, Dale S. Gregerson, Heidi Roehrich
Publikováno v:
Acta Neuropathologica Communications
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-19 (2018)
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-19 (2018)
Using mice expressing green fluorescent protein (GFP) from a transgenic CD11c promoter we found that a controlled optic nerve crush (ONC) injury attracted GFPhi retinal myeloid cells to the dying retinal ganglion cells and their axons. However, the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a363570e0c48531556ae80d7ad08b98f
http://europepmc.org/articles/PMC6055350
http://europepmc.org/articles/PMC6055350
Publikováno v:
Transactions of the American Ophthalmological Society. 115
Understanding the apparent paradoxical role of zinc in the pathogenesis and prevention of age-related macular degeneration (AMD) has been limited by the lack of animal models for its detection in sub-retinal epithelial deposits (drusen), a definitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6916b81f8719b8c6fc9969011d1d70e7
https://pubmed.ncbi.nlm.nih.gov/29021717
https://pubmed.ncbi.nlm.nih.gov/29021717
Publikováno v:
The Journal of Immunology. 190:4971-4981
Extrathymically derived regulatory T cells (iTregs) protect against autoimmunity to tissue-specific antigens (Ag). However, whether Ag-specific iTreg generation and function is limited to secondary lymphoid tissue or whether it can occur within the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45caaaabc93f3329d0640e1f2926a92f
https://doi.org/10.4049/jimmunol.1202625
https://doi.org/10.4049/jimmunol.1202625
Publikováno v:
The Journal of Immunology. 188:1191-1200
Interest in the identities, properties, functions, and origins of local APC in CNS tissues is growing. We recently reported that dendritic cells (DC) distinct from microglia were present in quiescent retina and rapidly responded to injured neurons. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1388a0d8898c7e90af0bd5bdf2ca97
https://doi.org/10.4049/jimmunol.1101621
https://doi.org/10.4049/jimmunol.1101621
Publikováno v:
Current Immunology Reviews. 7:344-349
Regulatory T cells (Tregs) are generated to antigens (Ag) found in the retina. Some Tregs are the result of ectopic expression of the retinal Ags in the thymus, where developing T cells are committed to enter the regulatory lineage. However, the gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4545e2094960a7856b58b3cb3659da3e
https://doi.org/10.2174/157339511796196584
https://doi.org/10.2174/157339511796196584