Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Scott W. Hall"'
Publikováno v:
Transfusion. 49:2583-2587
BACKGROUND: Most cases of human babesiosis in North America are caused by Babesia microti, which is endemic in the northeastern and upper midwestern United States. Although the disease is usually transmitted by a tick bite, there has been an increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7c373452914f5b63f7b944ebd79cc9b
https://doi.org/10.1111/j.1537-2995.2009.02454.x
https://doi.org/10.1111/j.1537-2995.2009.02454.x
Autor:
Lawrence L.K. Leung, James B. Rance, Helen Philippou, David A. Lane, Timothy Myles, Peter J. Grant, Scott W. Hall, Robert A. S. Ariëns
Publikováno v:
Journal of Biological Chemistry. 278:32020-32026
Factor XIII is activated by thrombin, and this reaction is enhanced by the presence of fibrin(ogen). Using a substrate-based screening assay for factor XIII activity complemented by kinetic analysis of activation peptide cleavage, we show by using th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a3bc43f9242923f4465a859ac1f3cf7
https://doi.org/10.1074/jbc.m305364200
https://doi.org/10.1074/jbc.m305364200
Publikováno v:
Europe PubMed Central
The activation of human platelets by alpha-thrombin is mediated in part by cleavage of the protease-activated receptor (PAR) 1 and 4 and by the glycoprotein (Ib)alpha, (Gp(Ib)alpha), which binds with high affinity to alpha-thrombin. Recent studies ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686c61085324c7ae237ecb83fad0a4e1
https://doi.org/10.1021/bi010491f
https://doi.org/10.1021/bi010491f
Autor:
Ming Bao, Vanitha Ramakrishnan, Francis DeGuzman, David R. Phillips, Lawrence L.K. Leung, Scott W. Hall
Publikováno v:
Proceedings of the National Academy of Sciences. 98:1823-1828
Glycoprotein (GP) V is a major substrate cleaved by the protease thrombin during thrombin-induced platelet activation. Previous analysis of platelets from GP V-null mice suggested a role for GP V as a negative modulator of platelet activation by thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d1e194f310f3932877962a9fc813d9
https://doi.org/10.1073/pnas.98.4.1823
https://doi.org/10.1073/pnas.98.4.1823
Publikováno v:
Thrombosis and Haemostasis. 86:1466-1474
SummaryThrombin binding to fibrin may be important in localizing thrombin to the site of vascular injury. However, fibrin-bound thrombin retains its catalytic activity toward fibrinogen, and may be prothrombotic under certain conditions. A collection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94093b1a5c4d66a37386b31b55d70f26
https://doi.org/10.1055/s-0037-1616750
https://doi.org/10.1055/s-0037-1616750
Autor:
Lawrence L.K. Leung, Scott W. Hall
Publikováno v:
Trends in Cardiovascular Medicine. 10:89-92
Thrombin is an allosteric enzyme that interacts with multiple procoagulant substrates such as specific clotting factors and cell surface thrombin receptors, as well as the anticoagulant substrate protein C. Functional mapping of thrombin's interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c7a10d6f206941ff426b9d4ad9229d
https://doi.org/10.1016/s1050-1738(00)00047-5
https://doi.org/10.1016/s1050-1738(00)00047-5
Publikováno v:
Transfusion. 49(12)
Most cases of human babesiosis in North America are caused by Babesia microti, which is endemic in the northeastern and upper midwestern United States. Although the disease is usually transmitted by a tick bite, there has been an increase in the numb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a590ebbeef03be2d6dac62e68127bf9
https://pubmed.ncbi.nlm.nih.gov/19906041
https://pubmed.ncbi.nlm.nih.gov/19906041
Publikováno v:
Journal of Biological Chemistry. 266:12329-12336
The purpose of this investigation was to characterize the reaction of alpha 2-antiplasmin (alpha 2AP) and alpha 2-macroglobulin (alpha 2M) with human plasmin bound to rat C6 glioma cells and human umbilical vein endothelial cells (HUVECs). Binding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::926402ae11fdc5fa8893ac7313875c3c
https://doi.org/10.1016/s0021-9258(18)98900-3
https://doi.org/10.1016/s0021-9258(18)98900-3
Autor:
Steven L. Gonias, Jonathan LaMarre, Isa M. Hussaini, Scott W. Hall, M A Hayes, G K Wollenberg
Publikováno v:
Journal of Clinical Investigation. 87:39-44
Radioiodinated transforming growth factor-beta 1 (TGF-beta 1) bound to the plasma proteinase inhibitor, alpha 2-macroglobulin (alpha 2M), as determined by chromatography on Superose-6 and native polyacrylamide gel electrophoresis. When alpha 2M confo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d2d160a2adf14d46a14de71105091e
https://doi.org/10.1172/jci114998
https://doi.org/10.1172/jci114998
Publikováno v:
Journal of Cellular Biochemistry. 43:213-227
The human (Glu1)-plasminogen carbohydrate isozymes, plasminogen type I (Pg 1) and plasminogen type II (Pg 2), were separated by chromatography and studied in cell binding experiments at 4{degrees}C with primary cultures of rat hepatocytes and rat C6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0458b0a7f97809599495915578b05769
https://doi.org/10.1002/jcb.240430303
https://doi.org/10.1002/jcb.240430303