Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Scott W, Cousins"'
Autor:
Justis P. Ehlers, MD, Allen Hu, MD, David Boyer, MD, Scott W. Cousins, MD, Nadia K. Waheed, MD, Philip J. Rosenfeld, MD, PhD, David Brown, MD, Peter K. Kaiser, MD, Anthony Abbruscato, PharmD, Gui Gao, PhD, Jeffrey Heier, MD, Prema Abraham, Christopher Devine, Anita Schadlu, George Novalis, Derek Y. Kunimoto, John Parchue, Suk Jin Moon, Zachary Segal, Dennis Marcus, Paul Hahn, Eric Suan, Michael Lee, Victor Gonzalez, Michael A. Samuel, Sunil Patel, Patrick Williams, Brian B. Berger, Henry Kwong, Dante Pieramici, Eric W. Schneider, Yevgeniy Shildkrot, Mathew T. Witmer, Nathan Steinle, Carmelina Gordon, Daniel Learned, Patrick Higgins, Guruprasad Pattar, Vijay Khetpal, Robin Ross, Mark R. Barakat, Sun Young Lee Sjatkowski, David Lally, Troy Becker
Publikováno v:
Ophthalmology Science, Vol 5, Iss 1, Pp 100628- (2025)
Objective: This study evaluated the safety and efficacy of elamipretide in dry age-related macular degeneration (AMD) with noncentral geographic atrophy (GA). Design: ReCLAIM-2 was a prospective, phase II, randomized, placebo-controlled, double-maske
Externí odkaz:
https://doaj.org/article/7164fb5412894bafbf1cb11d512f531f
Publikováno v:
Ophthalmology Science, Vol 2, Iss 1, Pp 100086- (2022)
Purpose: Assess the safety, tolerability, and feasibility of subcutaneous administration of the mitochondrial-targeted drug elamipretide in patients with dry age-related macular degeneration (AMD) and noncentral geographic atrophy (NCGA) and to perfo
Externí odkaz:
https://doaj.org/article/06ec418bb89643339039f47dbed8de5b
Publikováno v:
Ophthalmology Science, Vol 2, Iss 1, Pp 100095- (2022)
Purpose: To assess safety, tolerability, and feasibility of subcutaneous administration of the mitochondrial-targeted drug elamipretide in patients with intermediate age-related macular degeneration (AMD) and high-risk drusen (HRD) and to perform exp
Externí odkaz:
https://doaj.org/article/564ea67338bb440da4473a2951dec362
Autor:
Jie Zhuang, David J. Madden, Priscila Cunha, Alexandra Badea, Simon W. Davis, Guy G. Potter, Eleonora M. Lad, Scott W. Cousins, Nan-Kuei Chen, Kala Allen, Abigail J. Maciejewski, Xuan Duong Fernandez, Michele T. Diaz, Heather E. Whitson
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102594- (2021)
Age-related macular degeneration (AMD) is a common retina disease associated with cognitive impairment in older adults. The mechanism(s) that account for the link between AMD and cognitive decline remain unclear. Here we aim to shed light on this iss
Externí odkaz:
https://doaj.org/article/7a157163c7b740429d4ba986b29534f4
Autor:
Matias Soifer, Nadim S. Azar, Ricardo Blanco, Hazem M. Mousa, Seyyedehfatemeh Ghalibafan, Arianna Tovar, Priyatham S. Mettu, Michael J. Allingham, Scott W. Cousins, Alfonso L. Sabater, Victor L. Perez
Publikováno v:
Ocul Surf
Punctate epithelial erosion (PEE) is a corneal sign of dry eye disease (DED), which is observable via staining with fluorescein on slit lamp as a standard of clinical practice and clinical research. There are currently many limitations for detecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da60ca8b8d4808dbbbc15dfcff1676b
https://doi.org/10.1016/j.jtos.2022.11.010
https://doi.org/10.1016/j.jtos.2022.11.010
Autor:
Eleonora M Lad, Dibyendu Mukherjee, Sandra S Stinnett, Scott W Cousins, Guy G Potter, James R Burke, Sina Farsiu, Heather E Whitson
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192646 (2018)
Inner retina in Alzheimer's Disease (AD) may experience neuroinflammation resulting in atrophy. The objective of our study was to determine whether retinal GCIPL (ganglion cell-inner plexiform layer) or nerve fiber layer (NFL) thickness may serve as
Externí odkaz:
https://doaj.org/article/baa388d502124b29a779a87bae924496
Autor:
Alexandra J. Horne, Kimberly S. Chiew, Jie Zhuang, Linda K. George, R. Alison Adcock, Guy G. Potter, Eleonora M. Lad, Scott W. Cousins, Frank R. Lin, Sara K. Mamo, Nan-Kuei Chen, Abigail J. Maciejewski, Xuan Duong Fernandez, Heather E. Whitson
Publikováno v:
Journal of Aging Research, Vol 2018 (2018)
Despite increased rates of disease, disability, and social losses with aging, seniors consistently report higher levels of subjective well-being (SWB), a construct closely related to happiness, than younger adults. In this exploratory study, we utili
Externí odkaz:
https://doaj.org/article/24c2240ea4ce4895bd71becaad0882b7
Autor:
Scott W. Cousins, Majda Hadziahmetovic, Amanda Del Risco, Terry Lee, Joshua Amason, Joon-Bom Kim
Publikováno v:
J Vitreoretin Dis
Purpose: This work tests the feasibility of remote ophthalmic imaging to identify referable retinal abnormalities and assesses the effectiveness of color fundus photography (CFP) vs optical coherence tomography (OCT) for this purpose. Methods: This p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010fb55f45146315ccb70c65a3fd7947
https://doi.org/10.1177/24741264211044223
https://doi.org/10.1177/24741264211044223
Publikováno v:
Ophthalmology Science, Vol 2, Iss 1, Pp 100086-(2022)
Purpose To assess safety, tolerability, and feasibility of subcutaneous administration of mitochondrial targeted drug elamipretide in patients with dry age-related macular degeneration (AMD) and noncentral geographic atrophy (NCGA) and to perform exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8d56f916faec7cdda08f0e403e69210
http://www.sciencedirect.com/science/article/pii/S2666914521000889
http://www.sciencedirect.com/science/article/pii/S2666914521000889
Autor:
Eleonora M. Lad, Scott W. Cousins, Nan-kuei Chen, Guy G. Potter, David J. Madden, Jie Zhuang, Priscila Cunha, Xintong Zuo, Heather E. Whitson
Publikováno v:
Neurobiol Aging
AMD has been linked to memory deficits, with no established neural mechanisms. In order to describe how resting-state, brain network functional connectivity relates to memory and AMD status in older adults without dementia, we collected resting-state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfb37eea0cd0ec5b1a39688170dc9d8
https://doi.org/10.1016/j.neurobiolaging.2020.07.020
https://doi.org/10.1016/j.neurobiolaging.2020.07.020