Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Scott Visovatti"'
Autor:
Nicolas Philip, Hongyang Pi, Mahin Gadkari, Xin Yun, John Huetsch, Cissy Zhang, Robert Harlan, Aurelie Roux, David Graham, Larissa Shimoda, Anne Le, Scott Visovatti, Peter J. Leary, Sina A. Gharib, Catherine Simpson, Lakshmi Santhanam, Jochen Steppan, Karthik Suresh
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 1, Pp n/a-n/a (2023)
Abstract In pulmonary artery hypertension (PAH), emerging evidence suggests that metabolic abnormalities may be contributing to cellular dysfunction in PAH. Metabolic abnormalities such as glycolytic shift have been observed intracellularly in severa
Externí odkaz:
https://doaj.org/article/97025afab3c44d04bea6835abb15b53e
Autor:
Mahin Gadkari, Nicolas Philip, Cissy Zhang, John Huetsch, Xin Yun, Robert Harlan, David Graham, Larissa Shimoda, Anne Le, Catherine Simpson, Lakshmi Santhanam, Scott Visovatti, Jochen Steppan, Karthik Suresh
Publikováno v:
Physiology. 38
Background: Pulmonary arterial hypertension (PAH) is characterized by narrowing of the pulmonary arteries, endothelial cell dysfunction, and an increased vascular cell proliferation. Increased proliferation is also accompanied by glycolytic shift, wh
Publikováno v:
Heart failure clinics. 19(1)
Pulmonary arterial hypertension (PAH) associated with connective tissue disease (CTD) (CTD-PAH) is a devastating condition that may progress rapidly to cause right ventricular dysfunction, resulting in significant morbidity and mortality. The pathobi
Autor:
Lucas Rich, Nimai Patel, Syed Hyder, Victor Moles, Hitinder S. Gurm, PRACHI Agarwal, Scott Visovatti, Jonathan Haft, Thomas Cascino, Vallerie V. McLaughlin, Vikas Aggarwal
Publikováno v:
Journal of the American College of Cardiology. 81:818
Autor:
Lucas Rich, Nimai Patel, Syed N. Hyder, Hitinder Gurm, Victor Moles, Prachi P. Agarwal, Scott Visovatti, Jonathan Haft, Thomas Cascino, Vallerie V. Mclaughlin, Vikas Aggarwal
Publikováno v:
Journal of the Society for Cardiovascular Angiography & Interventions. 2:100589
Autor:
Baraa Zuhaili, Magdalena Fossum, Christoph Theopold, Raphael Gheerardyn, Elof Eriksson, Scott Visovatti, Feng Yao, Tobias Hirsch, Henry Svensson, Oliver Bleiziffer, Patrik Velander, Mike K. Chen, Daniela Hoeller
Publikováno v:
Wound Repair and Regeneration. 16:288-293
Diabetic wounds result in significant morbidity, prolonged hospitalization, and enormous health-care expenses. Pigs have been shown to have wound healing resembling that in humans. The aim of this study was to develop a large-animal model for diabeti
Autor:
Daniela Hoeller, Jarek Slama, Elof Eriksson, Scott Visovatti, Nicola Petrie, Jan Vranckx, Hanka Augustinova, Feng Yao
Publikováno v:
Wound Repair and Regeneration. 13:51-60
We have previously reported that endogenous vascular endothelial growth factor (VEGF) concentration in older pig wounds peaked later and at one-fourth the level of young pigs. These data suggested that VEGF might play a major role in the healing of f
Autor:
Patrick J. Skelly, Mufaddal Fatakdawala, Donald A. Harn, Elof Eriksson, Scott Visovatti, Akram A. Da’dara
Publikováno v:
Parasite Immunology. 24:179-187
Sm23 is an integral membrane protein expressed widely in the human parasitic worm Schistosoma mansoni. Sm23 has already been shown to elicit protective immune responses following immunization with peptides or DNA constructs. In this study, we evaluat
Autor:
Yogendra Kanthi, Matthew Hyman, Hui Liao, Amy Baek, Scott Visovatti, Nadia Sutton, Wakako Takabe, Chih-Wen Ni, Hanjoong Jo, David Pinsky
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 34
Atherosclerotic plaque rupture and thrombosis remains the leading cause of death in the United States. We investigated the role of CD39, a potent ecto-enzymatic regulator of platelet activation and leukocyte trafficking, in atherosclerosis. We genera
Autor:
Nadia R Sutton, Amy Baek, Hui Liao, Yogen Kanthi, Christopher Song, Scott Visovatti, David J Pinsky
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Background CD39 (ENTPD-1) is a membrane-spanning ectonucleotidase that is responsible for the phosphohydrolysis of ATP to ADP and ADP to AMP. As increased myocardial infarct sizes have been reported in murine CD39 knockout models when compared with c