Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Scott Valena"'
Autor:
Nikhil B. Ghate, Sungmin Kim, Yonghwan Shin, Jinman Kim, Michael Doche, Scott Valena, Alan Situ, Sangnam Kim, Suhn K. Rhie, Heinz-Josef Lenz, Tobias S. Ulmer, Shannon M. Mumenthaler, Woojin An
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Our recent work has shown that DCAF1 (also known as VprBP) is overexpressed in colon cancer and phosphorylates histone H2AT120 to drive epigenetic gene inactivation and oncogenic transformation. We have extended these observations by investi
Externí odkaz:
https://doaj.org/article/7b69ae10e0f54b54aa09dd6a990bac1b
Autor:
Emma Jane Fong, Mathias Bigger, Seungil Kim, Michael Doche, Scott Valena, Pratiksha Kshetri, Shannon Mumenthaler
Publikováno v:
Cancer Research. 83:2383-2383
Patient-derived tumor organoids (PDTOs) have been shown to be predictors of clinical response. While evidence suggests PDTOs are a more physiologically relevant cell model to use for drug discovery, challenges still exist to fully characterize their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed83f81dd3067dbc6836e7dd713e1863
https://doi.org/10.1158/1538-7445.am2023-2383
https://doi.org/10.1158/1538-7445.am2023-2383
Autor:
Scott Valena, Pratiksha Kshetri, Brandon Choi, Ah Young Yoon, Shohei Imamura, Seungil Kim, Michael E. Doche, Shannon M. Mumenthaler
Publikováno v:
Cancer Research. 82:3080-3080
Patient-derived tumor organoids (PDTOs) have recently been used as an innovative preclinical model to predict patient-specific drug responses. However, it is critical to establish high quality, reproducible, and well-annotated PDTOs that closely reca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d8485f1f5774fd62bf8af26c74c43da
https://doi.org/10.1158/1538-7445.am2022-3080
https://doi.org/10.1158/1538-7445.am2022-3080