Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Scott T. Wong"'
Publikováno v:
Proceedings of the National Academy of Sciences. 106:18890-18896
Neural activity can induce persistent strengthening or weakening of synapses, known as long-term potentiation (LTP) or long-term depression (LTD), respectively. As potential cellular mechanisms underlying learning and memory, LTP and LTD are generall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8885de1ad0cef1e1588ada8e0b065d6
https://doi.org/10.1073/pnas.0910659106
https://doi.org/10.1073/pnas.0910659106
Publikováno v:
The Journal of Molecular Diagnostics. 10:102-108
Denaturing high-performance liquid chromatography (DHPLC) purification of heteroduplexes has been reported as a method to increase sensitivity of the detection of low-level heteroplasmy by DNA sequencing, and DHPLC profiling has been suggested as a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fbd300f36f1e4d9e70defac4fe5858d
https://doi.org/10.2353/jmoldx.2008.070081
https://doi.org/10.2353/jmoldx.2008.070081
Autor:
Louis J. Muglia, Daniel R. Storm, Victor V. Pineda, Hongbing Wang, Guy C.-K. Chan, Scott T. Wong
Publikováno v:
The Journal of Neuroscience. 23:9710-9718
Mossy fiber/CA3 long-term potentiation (LTP) is hypothesized to depend on cAMP signals generated by Ca(2+)-stimulated adenylyl cyclases AC1 or AC8. AC1 gene knock-out mice (AC1(–)(/)(–)) show a partial reduction in mossy fiber LTP, suggesting tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5e96ab1cf5b605ca11e546a6649fab
https://doi.org/10.1523/jneurosci.23-30-09710.2003
https://doi.org/10.1523/jneurosci.23-30-09710.2003
Publikováno v:
Nature Neuroscience. 5:1302-1308
Myelin-associated glycoprotein (MAG), an inhibitor of axon regeneration, binds with high affinity to the Nogo-66 receptor (NgR). Here we report that the p75 neurotrophin receptor (p75(NTR)) is a co-receptor of NgR for MAG signaling. In cultured human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4a8468c9c8d0e5ae9b605cdea385f4c
https://doi.org/10.1038/nn975
https://doi.org/10.1038/nn975
Autor:
Xiao-bing Yuan, John R. Henley, Nicholas C. Spitzer, Hongjun Song, Guo Li Ming, Scott T. Wong, Mu-ming Poo
Publikováno v:
Nature. 417:411-418
Pathfinding by growing axons in the developing nervous system may be guided by gradients of extracellular guidance factors. Analogous to the process of chemotaxis in microorganisms, we found that axonal growth cones of cultured Xenopus spinal neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14ff67374a2a36c8d74c8369e246728
https://doi.org/10.1038/nature745
https://doi.org/10.1038/nature745
Autor:
Graeme Lowe, Guy C.-K. Chan, Anuj Gaggar, Scott T. Wong, Zhengui Xia, Kien Trinh, Daniel R. Storm, Beth M. Hacker, Geoffrey H. Gold
Publikováno v:
Neuron. 27(3):487-497
Cyclic nucleotide–gated ion channels in olfactory sensory neurons (OSNs) are hypothesized to play a critical role in olfaction. However, it has not been demonstrated that the cAMP signaling is required for olfactory-based behavioral responses, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e74c759ced0cef6d36bf27d1cfc67259
Autor:
Sabrina M. Ott, Rejean L. Idzerda, Eileen L. Watson, Dennis H. DiJulio, Kerry L. Jacobson, Scott T. Wong, Jean C. Singh, Daniel R. Storm
Publikováno v:
Journal of Biological Chemistry. 275:14691-14699
Capacitative Ca(2+) entry stimulates cAMP synthesis in mouse parotid acini, suggesting that one of the Ca(2+)-sensitive adenylyl cyclases (AC1 or AC8) may play an important role in the regulation of parotid function (Watson, E. L., Wu, Z., Jacobson,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89050ab002f297a7edd686325c85fcfa
https://doi.org/10.1074/jbc.275.19.14691
https://doi.org/10.1074/jbc.275.19.14691
Autor:
Louis J. Muglia, Jaime Athos, Daniel R. Storm, Charles Chavkin, Victor V. Pineda, Michele L. Schaefer, Xavier A. Figueroa, Scott T. Wong
Publikováno v:
Neuron. 23(4):787-798
It is hypothesized that Ca 2+ stimulation of calmodulin (CaM)–activated adenylyl cyclases (AC1 or AC8) generates cAMP signals critical for late phase LTP (L-LTP) and long-term memory (LTM). However, mice lacking either AC1 or AC8 exhibit normal L-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e8ffbb7d1b352a4b9b9e5a915a87f4
Autor:
Shigetoshi Yano, Gary A. Wayman, Soren Impey, Scott T. Wong, Jean-Christophe Deloulme, Karl Obrietan, Steve Poser, Daniel R. Storm, Guy C.-K. Chan
Publikováno v:
Neuron. 21:869-883
Although Ca2+-stimulated cAMP response element binding protein– (CREB-) dependent transcription has been implicated in growth, differentiation, and neuroplasticity, mechanisms for Ca2+-activated transcription have not been defined. Here, we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e2c0280a53f418492164e061ee127a3
https://doi.org/10.1016/s0896-6273(00)80602-9
https://doi.org/10.1016/s0896-6273(00)80602-9
Publikováno v:
Clinical Immunology and Immunopathology. 87:193-204
C1q selectively localizes at injured tissues, where it may function as a regulator of cell-matrix interactions. We show here that purified C1q, added to the culture medium of human gingival fibroblasts (HF) spread onto fibronectin substrates, elicite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e821ef948b9c3d77d4670986cc036f4c
https://doi.org/10.1006/clin.1997.4485
https://doi.org/10.1006/clin.1997.4485