Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Scott T Aoki"'
Autor:
Debra A Wadford, Robert C Kauffman, Jesse D Deere, Scott T Aoki, Richard A Stanton, Joanne Higgins, Koen K A Van Rompay, Andradi Villalobos, James H Nettles, Raymond F Schinazi, Niels C Pedersen, Thomas W North
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86997 (2014)
RT-SHIV is a chimera of simian immunodeficiency virus (SIV) containing the reverse transcriptase (RT)-encoding region of human immunodeficiency virus type 1 (HIV-1) within the backbone of SIVmac239. It has been used in a non-human primate model for s
Externí odkaz:
https://doaj.org/article/5f1423224fd94d54b2ae48fbe6d694ee
Autor:
Scott T. Aoki, Douglas F. Porter, Aman Prasad, Marvin Wickens, Craig A. Bingman, Judith Kimble
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3769-3775 (2018)
Summary: FOG-3 is a master regulator of sperm fate in Caenorhabditis elegans and homologous to Tob/BTG proteins, which in mammals are monomeric adaptors that recruit enzymes to RNA binding proteins. Here, we determine the FOG-3 crystal structure and
Externí odkaz:
https://doaj.org/article/f317025531f3428a9fa1c9ecfd373326
Publikováno v:
RNA
Robust methods are critical for testing the in vivo regulatory mechanism of RNA binding proteins. Here we report improvement of a protein–mRNA tethering assay to probe the function of an RNA binding protein in its natural context within the C. eleg
Autor:
Craig A. Bingman, Scott T. Aoki, Douglas F. Porter, Judith Kimble, Aman Prasad, Marvin Wickens
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3769-3775 (2018)
Cell reports
Cell reports
SUMMARY FOG-3 is a master regulator of sperm fate in Caenorhabditis elegans and homologous to Tob/BTG proteins, which in mammals are monomeric adaptors that recruit enzymes to RNA binding proteins. Here, we determine the FOG-3 crystal structure and i
Publikováno v:
Proceedings of the National Academy of Sciences. 113:1279-1284
Cellular RNA-protein (RNP) granules are ubiquitous and have fundamental roles in biology and RNA metabolism, but the molecular basis of their structure, assembly, and function is poorly understood. Using nematode "P-granules" as a paradigm, we focus
Autor:
Tina R. Lynch, Craig A. Bingman, Scott T. Aoki, Judith Kimble, Marvin Wickens, Sarah L. Crittenden
SummaryCytoplasmic RNA-protein (RNP) granules have diverse biophysical properties, from liquid to solid, and play enigmatic roles in RNA metabolism. Nematode P-granules are paradigmatic liquid droplet granules and central to germ cell development. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5edff5d0395358a6801d720bb9b40e
Publikováno v:
The FASEB Journal. 32
Autor:
Craig A. Bingman, Aman Prasad, Judith Kimble, Marvin Wickens, Scott T. Aoki, Douglas F. Porter
Metazoan germ cells develop as sperm or oocytes, depending on chromosomal sex, extrinsic signaling from somatic tissue and intrinsic factors within the germ cells. Gamete fate regulatory networks have been analyzed in nematodes, flies and mammals, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c57ff062b2f2d1fe45f03d29641630f
https://doi.org/10.1101/088914
https://doi.org/10.1101/088914
Autor:
Robert M. Goeken, Ilnour Ourmanov, Alicia Buckler-White, Vanessa M. Hirsch, Charles R. Brown, Ronald J. Plishka, Fan Wu, Scott T. Aoki, Takeo Kuwata, Ranjini Iyengar
Publikováno v:
Journal of Virology. 86:8835-8847
Simian immunodeficiency virus (SIV) infection of rhesus macaques has become an important surrogate model for evaluating HIV vaccine strategies. The extreme resistance to neutralizing antibody (NAb) of many commonly used strains, such as SIVmac251/239
Cross-Linking of Rotavirus Outer Capsid Protein VP7 by Antibodies or Disulfides Inhibits Viral Entry
Autor:
Philip R. Dormitzer, Barbara S. Coulson, Harry B. Greenberg, Shane D. Trask, Stephen C. Harrison, Scott T. Aoki
Publikováno v:
Journal of Virology. 85:10509-10517
Antibodies that neutralize rotavirus infection target outer coat proteins VP4 and VP7 and inhibit viral entry. The structure of a VP7-Fab complex (S. T. Aoki, et al., Science 324:1444-1447, 2009) led us to reclassify epitopes into two binding regions