Zobrazeno 1 - 10 of 41 pro vyhledávání: '"Scott T, Laughlin"'
1
Self-Patterned Nanoscale Topography of Thin Copolymer Films Prepared by Evaporative Assembly-Resist Early-Stage Bacterial Adhesion
Autor: Jiachun Shen, Danielle Guercio, Ilana L. Heckler, Ting Jiang, Scott T. Laughlin, Elizabeth M. Boon, Surita R. Bhatia
Publikováno v: ACS Appl Bio Mater
Biofilm formation on the surfaces of indwelling medical devices has become a growing health threat due to the development of antimicrobial resistance to infection-causing bacteria. For example, ventilator-associated pneumonia caused by Pseudomonas an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824e5945587f1960f78d5c192442ba53
https://pubmed.ncbi.nlm.nih.gov/35895111
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2
Modular Enzyme‐ and Light‐Based Activation of Cyclopropene–Tetrazine Ligation
Autor: Adrian O. Thompson, Wei Huang, Wei-Siang Kao, Frank M. Camarda, Pratik Kumar, Scott T. Laughlin, Ting Jiang
Publikováno v: ChemBioChem. 20:2222-2226
We describe a modular activation strategy for cyclopropene-tetrazine ligation. This activation strategy uses chemically diverse enzyme- or photolabile protecting groups as cyclopropene reactivity cages. The linkages between the caging groups and cycl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35dc4862ac8b6bdd1b9990ac5262f7df
https://doi.org/10.1002/cbic.201900137
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3
Stable cyclopropene-containing analogs of the amino acid neurotransmitter glutamate
Autor: Frank M. Camarda, Scott T. Laughlin, Pratik Kumar, Wei Huang, David Shukhman
Publikováno v: Tetrahedron Letters. 60:1476-1480
As a neurotransmitter, the amino acid glutamate has been the subject of efforts to generate structural analogs with unique properties. Here we report a practical, half-gram synthesis of two cyclopropene-containing glutamate analogs. These analogs are
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e021c073326ab8896559cf5b663b9685
https://doi.org/10.1016/j.tetlet.2019.04.046
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4
Controlling Rheology of Fluid Interfaces through Microblock Length of Sequence‐Controlled Amphiphilic Copolymers
Autor: Xiaoxi Yu, Guofang Li, Bingqian Zheng, Gyusaang Youn, Ting Jiang, Suan P. Quah, Scott T. Laughlin, Nicole S. Sampson, Surita R. Bhatia
Publikováno v: Macromolecular Chemistry and Physics. 223:2270041
Previous studies have demonstrated that films of sequence-controlled amphiphilic copolymers display contact angles that depend on microblock size. This suggests that microblock length may provide a means of tuning surface and interfacial properties.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79fc33eb0aa6b975d01821fbfc20a29d
https://doi.org/10.1002/macp.202270041
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10
Enzyme- or light-triggered cyclopropenes for bioorthogonal ligation
Autor: Ting, Jiang, Scott T, Laughlin
Publikováno v: Methods in enzymology. 641
Since first reported at the beginning of the 21st century, bioorthogonal reactions have become powerful tools for investigating biological systems. Here, we review several classic and current bioorthogonal reactions, including the Staudinger-Bertozzi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19dc28e66b55928b630531085b84fc99
https://pubmed.ncbi.nlm.nih.gov/32713519
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