Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Scott Seitz"'
Autor:
Qing Xia, Zhongyue Guo, Haonan Zong, Scott Seitz, Celalettin Yurdakul, M. Selim Ünlü, Le Wang, John H. Connor, Ji-Xin Cheng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Clinical identification and fundamental study of viruses rely on the detection of viral proteins or viral nucleic acids. Yet, amplification-based and antigen-based methods are not able to provide precise compositional information of individu
Externí odkaz:
https://doaj.org/article/218542972acc45938a7e29b2c2c565ab
Autor:
Victoria Overbeck, Bradford P. Taylor, Jacquelyn Turcinovic, Xueting Qiu, Beau Schaeffer, Scott Seitz, Scott R. Curry, William P. Hanage, John H. Connor, Krutika Kuppalli
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23699- (2024)
Background: Immunocompromised patients receiving B-cell-depleting therapies are at increased risk of persistent SARS-CoV-2 infection, with many experiencing fatal outcomes. We report a successful outcome in a patient with rheumatoid arthritis (RA) on
Externí odkaz:
https://doaj.org/article/9d0297be99844833b7bca6b7f072d815
Autor:
Da-Yuan Chen, Jacquelyn Turcinovic, Shuchen Feng, Devin J. Kenney, Chue Vin Chin, Manish C. Choudhary, Hasahn L. Conway, Marc Semaan, Brianna J. Close, Alexander H. Tavares, Scott Seitz, Nazimuddin Khan, Sebastian Kapell, Nicholas A. Crossland, Jonathan Z. Li, Florian Douam, Susan C. Baker, John H. Connor, Mohsan Saeed
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106634- (2023)
Summary: A simple and robust cell culture system is essential for generating authentic SARS-CoV-2 stocks for evaluation of viral pathogenicity, screening of antiviral compounds, and preparation of inactivated vaccines. Evidence suggests that Vero E6,
Externí odkaz:
https://doaj.org/article/4ef512ed285e4127ae84089843aedd7f
Autor:
Judith Olejnik, Adam J. Hume, Stephen J. Ross, Whitney A. Scoon, Scott Seitz, Mitchell R. White, Ben Slutzky, Nadezhda E. Yun, Elke Mühlberger
Publikováno v:
Pathogens, Vol 12, Iss 7, p 952 (2023)
The study of highly pathogenic viruses handled under BSL-4 conditions and classified as Select Agents frequently involves the transfer of inactivated materials to lower containment levels for downstream analyses. Adhering to Select Agent and BSL-4 sa
Externí odkaz:
https://doaj.org/article/c26bcb4efaf34936bdb613d5b61dc334
Autor:
RuthMabel Boytz, Scott Seitz, Emily Gaudiano, J. J. Patten, Patrick T. Keiser, John H. Connor, Arlene H. Sharpe, Robert A. Davey
Publikováno v:
Viruses, Vol 15, Iss 1, p 43 (2022)
Viral pathogens with the potential to cause widespread disruption to human health and society continue to emerge or re-emerge around the world. Research on such viruses often involves high biocontainment laboratories (BSL3 or BSL4), but the developme
Externí odkaz:
https://doaj.org/article/7a59686be2524014ba58bcddcfe3cb14
Autor:
Stephanie Bonney, Scott Seitz, Caitlin A. Ryan, Kenneth L. Jones, Penny Clarke, Kenneth L. Tyler, Julie A. Siegenthaler
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Blood-brain barrier (BBB) breakdown is a hallmark of many diseases of the central nervous system (CNS). Loss of BBB integrity in CNS diseases such as viral encephalitis results in the loss of nutrient/oxygen delivery, rapid infiltration of i
Externí odkaz:
https://doaj.org/article/18042d5bcef942dc9e29b2d759c37236
Autor:
Tara C Bouton, Joseph Atarere, Jacquelyn Turcinovic, Scott Seitz, Cole Sher-Jan, Madison Gilbert, Laura White, Zhenwei Zhou, Mohammad M Hossain, Victoria Overbeck, Lynn Doucette-Stamm, Judy Platt, Hannah E Landsberg, Davidson H Hamer, Catherine Klapperich, Karen R Jacobson, John H Connor
Publikováno v:
Clinical Infectious Diseases. 76:e227-e233
BackgroundIn January 2022, US guidelines shifted to recommend isolation for 5 days from symptom onset, followed by 5 days of mask-wearing. However, viral dynamics and variant and vaccination impact on culture conversion are largely unknown.MethodsWe
Autor:
Victoria Overbeck, Jacquelyn Turcinovic, Xueting Qiu, Scott Seitz, John Connor, Beau Schaeffer, William P Hanage, Scott R Curry, Krutika Kuppalli
Publikováno v:
Open Forum Infectious Diseases. 9
Background The COVID-19 pandemic has been marked by long-term persistence of SARS-CoV-2 in immunocompromised patients receiving B-cell-depleting therapies, with many individuals experiencing fatal COVID-19. Methods We report an individual treated wit
Autor:
Joseph Atarere, Zhenwei Zhou, Jacquelyn Turcinovic, Scott Seitz, Cole Sher-Jan, Madison Gilbert, Laura F White, Mohammad Hossain, Victoria Overbeck, Roxanne M Mistry, Lynn Doucette-Stamm, Judy T Platt, Hannah E Nichols, Davidson H Hamer, Catherine M Klapperich, Karen R Jacobson, John Connor, Tara C Bouton
Publikováno v:
Open Forum Infectious Diseases. 9
Background Omicron rapidly replaced delta as the predominant strain causing COVID-19 related illness in the United States (US) in December 2021, the same month the US CDC reduced the recommended isolation period from 10 to 5 days for asymptomatic ind
Autor:
Lauren E. Brown, Scott Seitz, Ashley V. Kondas, Paul T. Marcyk, Claire Marie Filone, Mohammad M. Hossain, Scott E. Schaus, Victoria A. Olson, John H. Connor
Publikováno v:
Antimicrob Agents Chemother
The genus Orthopoxvirus contains several human pathogens, including vaccinia, monkeypox, cowpox, and variola virus, the causative agent of smallpox. Although there are a few effective vaccines, widespread prophylactic vaccination has ceased and is un