Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Scott R. Rossi"'
Publikováno v:
Acta Ophthalmologica. 67:95-101
We have continued our study of the tear film and ocular surface in our full KCS (keratoconjunctivitis sicca) rabbit model up to 52 weeks post-operatively. Tear film osmolarity remains elevated, conjunctival goblet cell density remains decreased, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcae9f43b8a887c35b880fed72afc5a4
https://doi.org/10.1111/j.1755-3768.1989.tb07100.x
https://doi.org/10.1111/j.1755-3768.1989.tb07100.x
Autor:
Scott R. Rossi, Jeffrey P. Gilbard
Publikováno v:
Ophthalmology. 99:600-604
Thirty-two rabbits with monocular surgically induced keratoconjunctivitis sicca (KCS) underwent masked treatment for 12 weeks with 1 of 4 artificial tear solutions. Disease in each group of treated rabbits was compared with disease in untreated KCS c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0622e56cdc600ad23daabdde787e2f6d
https://doi.org/10.1016/s0161-6420(92)31929-3
https://doi.org/10.1016/s0161-6420(92)31929-3
Autor:
Jeffrey P. Gilbard, Scott R. Rossi
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461360254
The tear film has a unique electrolyte balance distinct from aqueous humor and serum.1. We postulated that this electrolyte balance was critical for the maintenance of ocular surface health.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b5209b9e3b4783db81e9eaf73e8e9a5
https://doi.org/10.1007/978-1-4615-2417-5_80
https://doi.org/10.1007/978-1-4615-2417-5_80
Autor:
Jeffrey P. Gilbard, Scott R. Rossi
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461360254
Meibomian gland dysfunction and autoimmune lacrimal gland disease both increase tear film osmolarity, the former by an increase in tear film evaporation, and the later by a decrease in tear secretion.1 In both cases the surface disease that results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a78fde7958e21b44cacf8745d8737043
https://doi.org/10.1007/978-1-4615-2417-5_89
https://doi.org/10.1007/978-1-4615-2417-5_89
Publikováno v:
Archives of ophthalmology (Chicago, Ill. : 1960). 109(5)
We examined the effect of topically applied 3-isobutyl-1-methylxanthine (IBMX), a known secretagogue, on tear secretion and dry-eye disease in a clinical study. We found that IBMX produced a dose-dependent decrease in tear film osmolarity that was si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0fb67180e20ec2bd0907c3f800818f
https://pubmed.ncbi.nlm.nih.gov/1709002
https://pubmed.ncbi.nlm.nih.gov/1709002
Autor:
Scott R. Rossi, Jeffrey P. Gilbard
Publikováno v:
Ophthalmology. 97(3)
The authors studied the tear film and ocular surface in a rabbit model of neurotrophic keratitis to determine the extent to which the surface disease of neurotrophic keratitis resembled keratoconjunctivitis sicca. After denervation, tear film osmolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3320f80326f9abfda561119edb563aa
https://pubmed.ncbi.nlm.nih.gov/2336268
https://pubmed.ncbi.nlm.nih.gov/2336268
Publikováno v:
Current eye research. 9(3)
Eledoisin has been tried as a possible treatment for dry eye based on the hypothesis that it pharmacologically stimulates tear secretion when topically applied to the eye. To determine if topically applied eledoisin pharmacologically stimulates orbit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78c67972de3a41242d8228c90e527a0
https://pubmed.ncbi.nlm.nih.gov/2347204
https://pubmed.ncbi.nlm.nih.gov/2347204
Publikováno v:
Ophthalmology. 96:1180-1186
To determine whether meibomian gland dysfunction can increase tear film osmolarity and produce ocular surface changes analogous to those seen with lacrimal gland disease (keratoconjunctivitis sicca [KCS]), the authors closed the meibomian gland orifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4cb4af09a5bf3c2df1004a26a11b220
https://doi.org/10.1016/s0161-6420(89)32753-9
https://doi.org/10.1016/s0161-6420(89)32753-9
Autor:
Rebecka Belldegrun, Kathleen L. Gray, Julie S. Lee, Jeffrey P. Gilbard, Scott R. Rossi, Andrew J.W. Huang
Publikováno v:
Ophthalmology. 96:244-246
The authors evaluated the efficacy of all-trans retinoic acid (vitamin A) ointment as a treatment for keratoconjunctivitis sicca (KCS) in a group of 11 patients selected on the basis of clinical history, slit-lamp examination results, rose Bengal sta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::132a18abc36714dfb12602da8630c865
https://doi.org/10.1016/s0161-6420(89)32909-5
https://doi.org/10.1016/s0161-6420(89)32909-5
Publikováno v:
American journal of ophthalmology. 107(4)
In rabbit studies, we found that extended exposure of the ocular surface to existing ophthalmic solutions resulted in gross surface abnormalities and decreases in conjunctival goblet cell density. We developed an electrolyte solution (solution 15) th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74be5e5485e5fe3f88c3ab15f01efddd
https://pubmed.ncbi.nlm.nih.gov/2750846
https://pubmed.ncbi.nlm.nih.gov/2750846