Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Scott R. Henderson"'
Autor:
Tai-Ying Chu, Céline Zheng-Gérard, Kuan-Yeh Huang, Yu-Chi Chang, Ying-Wen Chen, Kuan-Yu I, Yu-Ling Lo, Nien-Yi Chiang, Hsin-Yi Chen, Martin Stacey, Siamon Gordon, Wen-Yi Tseng, Chiao-Yin Sun, Yen-Mu Wu, Yi-Shin Pan, Chien-Hao Huang, Chun-Yen Lin, Tse-Ching Chen, Kamel El Omari, Marilina Antonelou, Scott R. Henderson, Alan Salama, Elena Seiradake, Hsi-Hsien Lin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Activation of neutrophil leukocytes is tightly regulated, and it is important to understand the molecular mechanisms of their response to physiological and pathological stimuli. Here authors show that the adhesion molecule G protein-coupled receptor
Externí odkaz:
https://doaj.org/article/b5cfd5e14a0d4c268333705e3a855d3c
Autor:
Scott R Henderson, Harry Horsley, Paul Frankel, Maryam Khosravi, Talya Goble, Stephen Carter, Marilina Antonelou, Rhys D R Evans, Xiang Zhang, Tai-Ying Chu, Hsi-Hsien Lin, Siamon Gordon, Alan David Salama
Publikováno v:
Annals of the Rheumatic Diseases. 82:848-856
ObjectivesGranulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are autoimmune vasculitides associated with antineutrophil cytoplasm antibodies that target proteinase 3 (PR3) or myeloperoxidase (MPO) found within neutrophils and m
Autor:
Charn Gill, Joseph Sturman, Leyla Ozbek, Scott R Henderson, Aine Burns, Sally Hamour, Ruth J Pepper, Lisha McClelland, Dimitrios Chanouzas, Simon Gane, Alan D Salama, Lorraine Harper
Publikováno v:
Rheumatology Advances in Practice. 7
Objectives Cocaine and cocaine mixed with levamisole are increasingly used in the UK and result in significant direct nasal damage in addition to promoting vasculitis. Our aims were as follows: (1) to identify the main symptoms and presentation of co
Autor:
Geraldine Cambridge, David A. Isenberg, Loren Kell, Samuel J Taylor, Maria J. Leandro, Kavina Shah, Ruth J Pepper, Venkat Reddy, Mark S. Cragg, Scott R. Henderson, Christian Klein
Publikováno v:
Rheumatology. 61:2894-2904
Objectives To investigate key factors that may contribute to the variability of rituximab-mediated peripheral and renal B cell depletion (BCD) in SLE. Methods We analysed: (i) CD19+ B cell counts in patients with SLE before and 1, 2, 3 and 6 months a
Autor:
Scott R. Henderson, Mark Harber
Publikováno v:
Primer on Nephrology ISBN: 9783030764180
Practical Nephrology ISBN: 9781447155461
Practical Nephrology ISBN: 9781447155461
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196ebe83aa42e576728807704b3560b0
https://doi.org/10.1007/978-3-030-76419-7_2
https://doi.org/10.1007/978-3-030-76419-7_2
Autor:
Rhys Evans, Chun Jing Wang, Marilina Antonelou, Erik Michaëlsson, Lucy S. K. Walker, Rave-Itn Investigators, Robert J. Unwin, Alan D. Salama, Scott R. Henderson
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Myeloperoxidase released after neutrophil and monocyte activation can generate reactive oxygen species, leading to host tissue damage. Extracellular glomerular myeloperoxidase deposition, seen in ANCA-associated vasculitis, may enhance cr
Publikováno v:
Nephrology Dialysis Transplantation. 34:2007-2014
Salt intake as part of a western diet currently exceeds recommended limits, and the small amount found in the natural diet enjoyed by our Paleolithic ancestors. Excess salt is associated with the development of hypertension and cardiovascular disease
Autor:
Christoph A. Müller, Lourdes Ceron-Gutierrez, Scott R. Henderson, Rhys Evans, Marilina Antonelou, Gabriela Barcenas-Morales, Stephen B. Walsh, Alan D. Salama, Rainer Doffinger, Marilena Rega, Sanchutha Sathiananthamoorthy
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Increased extracellular sodium activates Th17 cells, which provide protection from bacterial and fungal infections. Whilst high salt diets have been shown to worsen autoimmune disease, the immunological consequences of clinical salt depletion are unk
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 37(2)
Crescentic glomerulonephritis (CGN) results from a diverse set of diseases associated with immune dysregulation and the breakdown of self-tolerance to a wide range of autoantigens, some known and some that remain unknown. Experimental data demonstrat
Autor:
Mathew Hutchinson, S.K. Todd, Philip N. Hawkins, Alan D. Salama, Scott R. Henderson, Ruth J. Pepper, Helen J. Lachmann
Publikováno v:
Abstracts Accepted for Publication.
Background Familial Mediterranean Fever (FMF) is caused by mutations in MEFV. The protein product pyrin is expressed in monocytes, neutrophils and eosinophils. Acute inflammatory attacks are accompanied by a dramatic hepatic acute phase response. S10