Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Scott R Whittemore"'
Autor:
Courtney T Shepard, Brandon L Brown, Morgan A Van Rijswijck, Rachel M Zalla, Darlene A Burke, Johnny R Morehouse, Amberly S Riegler, Scott R Whittemore, David SK Magnuson
Publikováno v:
eLife, Vol 12 (2023)
Spinal locomotor circuitry is comprised of rhythm generating centers, one for each limb, that are interconnected by local and long-distance propriospinal neurons thought to carry temporal information necessary for interlimb coordination and gait cont
Externí odkaz:
https://doaj.org/article/2fe9eeda317740ffa74b222679cc71bc
Autor:
Courtney T Shepard, Amanda M Pocratsky, Brandon L Brown, Morgan A Van Rijswijck, Rachel M Zalla, Darlene A Burke, Johnny R Morehouse, Amberley S Riegler, Scott R Whittemore, David SK Magnuson
Publikováno v:
eLife, Vol 10 (2021)
Long ascending propriospinal neurons (LAPNs) are a subpopulation of spinal cord interneurons that directly connect the lumbar and cervical enlargements. Previously we showed, in uninjured animals, that conditionally silencing LAPNs disrupted left-rig
Externí odkaz:
https://doaj.org/article/76d9111e10d94c34bf93f809c60aae3d
Autor:
George Z Wei, Sujata Saraswat Ohri, Nicolas K Khattar, Adam W Listerman, Catherine H Doyle, Kariena R Andres, Saravanan S Karuppagounder, Rajiv R Ratan, Scott R Whittemore, Michal Hetman
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249591 (2021)
Traumatic spinal cord injury (SCI) is a devastating neurological condition that involves both primary and secondary tissue loss. Various cytotoxic events including hypoxia, hemorrhage and blood lysis, bioenergetic failure, oxidative stress, endoplasm
Externí odkaz:
https://doaj.org/article/afcf059cd1dc42a1bcc67fbc7242ecef
Autor:
Lukasz P Slomnicki, George Wei, Darlene A Burke, Emily R Hodges, Scott A Myers, Christine D Yarberry, Johnny R Morehouse, Scott R Whittemore, Sujata Saraswat Ohri, Michal Hetman
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0249981 (2021)
The circadian gene expression rhythmicity drives diurnal oscillations of physiological processes that may determine the injury response. While outcomes of various acute injuries are affected by the time of day at which the original insult occurred, s
Externí odkaz:
https://doaj.org/article/f29cd798582847b9bb759213f45b5360
Autor:
Amanda M Pocratsky, Courtney T Shepard, Johnny R Morehouse, Darlene A Burke, Amberley S Riegler, Josiah T Hardin, Jason E Beare, Casey Hainline, Gregory JR States, Brandon L Brown, Scott R Whittemore, David SK Magnuson
Publikováno v:
eLife, Vol 9 (2020)
Within the cervical and lumbar spinal enlargements, central pattern generator (CPG) circuitry produces the rhythmic output necessary for limb coordination during locomotion. Long propriospinal neurons that inter-connect these CPGs are thought to secu
Externí odkaz:
https://doaj.org/article/1d2ab2ad153547348c5c71b83cd2cbee
Autor:
Guangyan Xiong, Sajedah M Hindi, Aman K Mann, Yann S Gallot, Kyle R Bohnert, Douglas R Cavener, Scott R Whittemore, Ashok Kumar
Publikováno v:
eLife, Vol 6 (2017)
Regeneration of skeletal muscle in adults is mediated by satellite stem cells. Accumulation of misfolded proteins triggers endoplasmic reticulum stress that leads to unfolded protein response (UPR). The UPR is relayed to the cell through the activati
Externí odkaz:
https://doaj.org/article/fac93d24e52749a8beb98981ad45d0b4
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e109703 (2014)
Activation of the endoplasmic reticulum stress response (ERSR) is a hallmark of various pathological diseases and/or traumatic injuries. Restoration of ER homeostasis can contribute to improvement in the functional outcome of these diseases. Using ge
Externí odkaz:
https://doaj.org/article/30585db519654aedaaec9b237d04bf2f
Publikováno v:
ASN Neuro, Vol 1 (2009)
Microvascular dysfunction, loss of vascular support, ischaemia and sub-acute vascular instability in surviving blood vessels contribute to secondary injury following SCI (spinal cord injury). Neither the precise temporal profile of the cellular dynam
Externí odkaz:
https://doaj.org/article/b42cfd3ec5b94a3ca8a44722306a48aa
Autor:
Sujata Saraswat Ohri, Kariena R. Andres, Russell M. Howard, Brandon L. Brown, Michael D. Forston, Michal Hetman, Scott R. Whittemore
Publikováno v:
Journal of Neurotrauma. 40:1007-1019
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c916c316425de9bde733219201e2184c
https://doi.org/10.1089/neu.2022.0177
https://doi.org/10.1089/neu.2022.0177
Autor:
Beatrice Ugiliweneza, Maxwell Boakye, Sujata Saraswat Ohri, Scott R. Whittemore, Michal Hetman
Publikováno v:
Journal of Neurotrauma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6702195bd47e1b7ad9ef1c9abfa5698f
https://doi.org/10.1089/neu.2022.0411
https://doi.org/10.1089/neu.2022.0411