Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Scott P. Hennelly"'
Autor:
Doo Nam Kim, Bernhard C. Thiel, Tyler Mrozowich, Scott P. Hennelly, Ivo L. Hofacker, Trushar R. Patel, Karissa Y. Sanbonmatsu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Many RNA systems possess highly ordered 3-D structures that are essential to their function. Here the authors demonstrate that the long non-coding RNA Braveheart possesses a flexible but defined 3-D structure which is remodeled upon binding the prote
Externí odkaz:
https://doaj.org/article/b7b190fd83ef4f3290654e561d22e685
Autor:
Emily J. Hawkes, Scott P. Hennelly, Irina V. Novikova, Judith A. Irwin, Caroline Dean, Karissa Y. Sanbonmatsu
Publikováno v:
Cell Reports, Vol 16, Iss 12, Pp 3087-3096 (2016)
There is considerable debate about the functionality of long non-coding RNAs (lncRNAs). Lack of sequence conservation has been used to argue against functional relevance. We investigated antisense lncRNAs, called COOLAIR, at the A. thaliana FLC locus
Externí odkaz:
https://doaj.org/article/40aa73c0d2a34525b4ac4573a34f318f
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 23672-23684 (2013)
RNAs are important catalytic machines and regulators at every level of gene expression. A new class of RNAs has emerged called long non-coding RNAs, providing new insights into evolution, development and disease. Long non-coding RNAs (lncRNAs) predom
Externí odkaz:
https://doaj.org/article/f9c1d7897bef4da4854c36f0eebd9134
Autor:
Naresh Pandey, Steffi A. Davison, Malathy Krishnamurthy, Daniel S. Trettel, Chien-Chi Lo, Shawn Starkenburg, Katherine L. Wozniak, Theresa L. Kern, Sean D. Reardon, Clifford J. Unkefer, Scott P. Hennelly, Taraka Dale
Publikováno v:
ACS synthetic biology. 11(10)
Engineered microbes can be used for producing value-added chemicals from renewable feedstocks, relieving the dependency on nonrenewable resources such as petroleum. These microbes often are composed of synthetic metabolic pathways; however, one major
Autor:
Susmitnarayan Chaudhury, Erdong Ding, Scott P. Hennelly, José Onuchic, Karissa Y. Sanbonmatsu
Publikováno v:
Biophysical Journal. 122:444a
Autor:
Susmita Roy, Raju Sarkar, Akhilesh Jaiswar, José N. Onuchic, Karissa Y. Sanbonmatsu, Scott P. Hennelly
Publikováno v:
J Phys Chem B
Magnesium plays a critical role in the structure, dynamics, and function of RNA. The precise microscopic effect of chelated magnesium on RNA structure is yet to be explored. Magnesium is known to act through its diffuse cloud around RNA, through the
Autor:
Taraka Dale, Jeremy M. Bingen, Scott P. Hennelly, Christopher W. Johnson, Ramesh K. Jha, Niju Narayanan, Gregg T. Beckham, Naresh Pandey, Theresa L. Kern, Charlie E. M. Strauss
Publikováno v:
ACS Synthetic Biology. 8:775-786
Product inhibition is a frequent bottleneck in industrial enzymes, and testing mutations to alleviate product inhibition via traditional methods remains challenging as many variants need to be tested against multiple substrate and product concentrati
Publikováno v:
Nucleic Acids Research
Investigations of most riboswitches remain confined to the ligand-binding aptamer domain. However, during the riboswitch mediated transcription regulation process, the aptamer domain and the expression platform compete for a shared strand. If the exp
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 23672-23684 (2013)
International Journal of Molecular Sciences, Vol 14, Iss 12, Pp 23672-23684 (2013)
RNAs are important catalytic machines and regulators at every level of gene expression. A new class of RNAs has emerged called long non-coding RNAs, providing new insights into evolution, development and disease. Long non-coding RNAs (lncRNAs) predom
Publikováno v:
Journal of Molecular Biology. 425:3731-3746
Novel, profound and unexpected roles of long non-coding RNAs (lncRNAs) are emerging in critical aspects of gene regulation. Thousands of lncRNAs have been recently discovered in a wide range of mammalian systems, related to development, epigenetics,