Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Scott Nawy"'
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106654- (2024)
Microphthalmia, mostly an autosomal dominant disorder, is a worldwide severe congenital ocular malformation that causes visual impairment. Our investigation unveiled a total of 30 genes associated with microphthalmia. Employing the CytoHubba and PPI
Externí odkaz:
https://doaj.org/article/5863910e798a4fb192ccc45ec74bb133
Publikováno v:
Cell Insight, Vol 3, Iss 3, Pp 100162- (2024)
The ciliary body, located at the junction of the choroid and iris, is crucial in the development of the embryonic eye. Notch2 signalling, Wnt signalling, transforming growth factor β (TGF-β) signalling, and Pax6 signalling are critical for coordina
Externí odkaz:
https://doaj.org/article/42664c9c3b7340e393c763c08ef8ee80
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Vision impairment and blindness in humans are most frequently caused by the degeneration and loss of photoreceptor cells in the outer retina, as is the case for age-related macular degeneration, retinitis pigmentosa, retinal detachment and many other
Externí odkaz:
https://doaj.org/article/53be21eaa2d047a8a7a24930fd342d61
Autor:
Asia L. Sladek, Scott Nawy
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 12 (2020)
AMPA-type glutamate receptors in the CNS are normally impermeable to Ca2+, but the aberrant expression of Ca2+-permeable AMPA receptors (CP-AMPARs) occurs in pathological conditions such as ischemia or epilepsy, or degenerative diseases such as ALS.
Externí odkaz:
https://doaj.org/article/2355cd23b34b4d468be3952f34370f62
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
The predominate type of AMPA receptor expressed in the CNS is impermeable to Ca2+ (CI-AMPAR). However, some AMPA receptors are permeable to Ca2+ (CP-AMPAR) and play important roles in development, plasticity and disease. In the retina, ganglion cells
Externí odkaz:
https://doaj.org/article/c7122cae204f4cf39cc3e7836983d50f
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91288 (2014)
Glaucoma is a progressive neurodegenerative disease of retinal ganglion cells (RGCs) associated with characteristic axon degeneration in the optic nerve. Excitotoxic damage due to increased Ca(2+) influx, possibly through NMDA-type glutamate receptor
Externí odkaz:
https://doaj.org/article/866fe62638bf44b8a5d4d811848daf5b
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 3, p e1002969 (2013)
Retinal ganglion cells receive inputs from multiple bipolar cells which must be integrated before a decision to fire is made. Theoretical studies have provided clues about how this integration is accomplished but have not directly determined the rule
Externí odkaz:
https://doaj.org/article/c6162ed0e5ea495a8891ac0f09496831
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Frontiers in Neuroscience
Frontiers in Neuroscience
Vision impairment and blindness in humans are most frequently caused by the degeneration and loss of photoreceptor cells in the outer retina, as is the case for age-related macular degeneration, retinitis pigmentosa, retinal detachment and many other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c42891e4e2508290da4b8ae28a14ee
https://www.frontiersin.org/articles/10.3389/fnins.2020.618019/full
https://www.frontiersin.org/articles/10.3389/fnins.2020.618019/full
Publikováno v:
eNeuro, vol 7, iss 5
eNeuro
eNeuro
Horizontal cells (HCs) form reciprocal synapses with rod and cone photoreceptors, an arrangement that underlies lateral inhibition in the retina. HCs send negative and positive feedback signals to photoreceptors, but how HCs initiate these signals re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffa1611b3cb8da6e31cb22bd3661431
https://escholarship.org/uc/item/0g1828r1
https://escholarship.org/uc/item/0g1828r1
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 12, Pp 1-14 (2019)
Cell Death and Disease, Vol 10, Iss 12, Pp 1-14 (2019)
Progressive degeneration of retinal ganglion cells (RGCs) will cause a blinding disease. Most of the study is focusing on the RGCs itself. In this study, we demonstrate a decline of the presynaptic rod bipolar cells (RBCs) response precedes RGCs loss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e057e2f83ebd70a8c987e54f37cefcb7
https://pubmed.ncbi.nlm.nih.gov/31787761
https://pubmed.ncbi.nlm.nih.gov/31787761