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pro vyhledávání: '"Scott N, VanderWel"'
Autor:
Scott N, VanderWel, Patricia J, Harvey, Dennis J, McNamara, Joseph T, Repine, Paul R, Keller, John, Quin, R John, Booth, William L, Elliott, Ellen M, Dobrusin, David W, Fry, Peter L, Toogood
Publikováno v:
Journal of medicinal chemistry. 48(7)
Inhibition of the cell cycle kinase, cyclin-dependent kinase-4 (Cdk4), is expected to provide an effective method for the treatment of proliferative diseases such as cancer. The pyrido[2,3-d]pyrimidin-7-one template has been identified previously as