Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Scott M. Steward-Tharp"'
Autor:
Pranav S. Renavikar, Sushmita Sinha, Ashley A. Brate, Nicholas Borcherding, Michael P. Crawford, Scott M. Steward-Tharp, Nitin J. Karandikar
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Autoimmune diseases are characterized by regulatory deficit in both the CD4+ and CD8+ T-cell compartments. We have shown that CD8+ T-cells associated with acute relapse of multiple sclerosis are significantly deficient in their immune suppressive abi
Externí odkaz:
https://doaj.org/article/7fb1ba252a3945ae9d86d876f40654ed
Autor:
Sushmita Sinha, Pranav S Renavikar, Michael P Crawford, Scott M Steward-Tharp, Ashley Brate, Eva Tsalikian, Michael Tansey, Ezzatollah T Shivapour, Tracey Cho, John Kamholz, Nitin J Karandikar
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238070 (2020)
Factors regulating self-antigen directed immune-responses in autoimmunity are poorly understood. Signal regulatory protein gamma (SIRPγ) is a human T-cell specific protein with genetic variants associated with type 1 diabetes (T1D). SIRPγ's functio
Externí odkaz:
https://doaj.org/article/1e55512d7b8a45a5a6a12f43ec8393a6
Autor:
Nitin J. Karandikar, Michael P. Crawford, Ashley A. Brate, Pranav S Renavikar, Scott M. Steward-Tharp, Sushmita Sinha, Nicholas Borcherding
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Autoimmune diseases are characterized by regulatory deficit in both the CD4+ and CD8+ T-cell compartments. We have shown that CD8+ T-cells associated with acute relapse of multiple sclerosis are significantly deficient in their immune suppressive abi
Autor:
Nitin J. Karandikar, Michael Tansey, John Kamholz, Pranav S Renavikar, Ashley A. Brate, Sushmita Sinha, Tracey Cho, Ezzatollah T. Shivapour, Scott M. Steward-Tharp, Eva Tsalikian, Michael P. Crawford
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0238070 (2020)
PLoS ONE
PLoS ONE
Factors regulating self-antigen directed immune-responses in autoimmunity are poorly understood. Signal regulatory protein gamma (SIRPγ) is a human T-cell specific protein with genetic variants associated with type 1 diabetes (T1D). SIRPγ's functio
Autor:
John W. Hellstein, Shahidul Ahsan, Felipe Nor, Joshua Orgill, N. Handoo, Sherry Timmons, Scott M. Steward-Tharp, Saulo Leonardo Sousa Melo
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 128:e54-e55
Objective The simple bone cyst is a benign intraosseous pseudocystic lesion without any epithelial lining. As most of simple bone cysts are asymptomatic, they are commonly first noticed as incidental radiographic findings. In the jaws, they are predo
Autor:
Saulo Leonardo Sousa Melo, S. Anamali-Allareddy, D. Alhazmi, Veeratrishul Allareddy, Scott M. Steward-Tharp
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 127:32-33
Background Mucoepidermoid carcinoma is the most common salivary gland malignancy. Approximately more than half these tumors present in the major salivary glands, the parotid gland being the most frequent location.1 The others occur in the minor saliv
Autor:
Sherry Timmons, Juan Pablo Castro Cuellar, Shahidul Ahsan, N. Handoo, Scott M. Steward-Tharp, Felipe Nor, S. Anamali
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 128:e69
Objective Central xanthoma of the jaw is an extraordinarily rare entity with less than 30 cases reported in the English literature so far. This benign lesion is often associated with endocrine and metabolic diseases (e.g. hyperlipidemia, diabetes mel
Autor:
Scott M. Steward-Tharp, Veeratrishul Allareddy, Saulo Leonardo Sousa Melo, S. Vijayan, S. Anamali-Allareddy
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 127:48
Background Ameloblastoma is a true neoplasm of odontogenic epithelium.1,2 It is a locally invasive, slow-growing, and persistent tumor.1-4 It is among the most common odontogenic tumors.1,2 Ameloblastoma can arise from dental lamina, dental organ, ep
Autor:
Jason W. Alsup, Michael I. Jesson, Jamie L. Lee, Craig J. Thomas, Richard D. Head, Martin E. Dowty, Zaher A. Radi, Scott M. Steward-Tharp, Kamran Ghoreschi, John J. O'Shea, Masao Tanaka, Debra M. Meyer, Timothy P. LaBranche, Chad E. Storer, Massimo Gadina, Xiong Li, James D. Warner, Sarbani Ghosh, Nandini Kishore, John C. Minnerly
Publikováno v:
The Journal of Immunology. 186:4234-4243
Inhibitors of the JAK family of nonreceptor tyrosine kinases have demonstrated clinical efficacy in rheumatoid arthritis and other inflammatory disorders; however, the precise mechanisms by which JAK inhibition improves inflammatory immune responses
Autor:
Hong-Wei Sun, Arian Laurence, Kamran Ghoreschi, Xiang-Ping Yang, Lai Wei, Yuka Kanno, John R. Grainger, Scott M. Steward-Tharp, John J. O'Shea, Golnaz Vahedi, Kiyoshi Hirahara, Jinfang Zhu, Jaime Rodriguez-Canales
Publikováno v:
Nature Immunology. 12:247-254
Interleukin 2 (IL-2), a cytokine linked to human autoimmune disease, limits IL-17 production. Here we found that deletion of the gene encoding the transcription factor STAT3 in T cells abrogated IL-17 production and attenuated autoimmunity associated