Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Scott M. Seki"'
Autor:
Scott M. Seki, Alban Gaultier
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
At the beginning of the twentieth century, discoveries in cancer research began to elucidate the idiosyncratic metabolic proclivities of tumor cells (1). Investigators postulated that revealing the distinct nutritional requirements of cells with unch
Externí odkaz:
https://doaj.org/article/cd1e6547f9a349efa310b057e534a95d
Publikováno v:
British Journal of Anaesthesia. 127:e69-e71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb1fe17e7d74feccaed2843c6de919c
https://doi.org/10.1016/j.bja.2021.05.016
https://doi.org/10.1016/j.bja.2021.05.016
Autor:
Charles Spivey, Scott M. Seki, Alban Gaultier, Vlad Serbulea, Anthony Fernandez-Castaneda, Nikolas William Hayes, Rebecca L. McCloud, Ku-Lung Hsu, Lelisa Gemta, Dorian A. Rosen, Sarah C. Nanziri, Kacper Posyniak, Timothy N. J. Bullock, Rebecca M. Beiter
Publikováno v:
Sci Signal
Immunometabolism
Immunometabolism
Small molecules that promote the metabolic activity of the pyruvate kinase isoform PKM2, such as TEPP-46 and DASA-58, limit tumorigenesis and inflammation. To understand how these compounds alter T cell function, we assessed their therapeutic activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8aee33d056a8440d07dfdc277416f4
https://doi.org/10.1126/scisignal.aay9217
https://doi.org/10.1126/scisignal.aay9217
Autor:
Scott M. Seki, Timothy N. J. Bullock, Max Stevenson, Abagail M. Rosen, Alban Gaultier, Lelisa Gemta, Sanja Arandjelovic
Publikováno v:
The Journal of Immunology. 198:4607-4617
Multiple sclerosis (MS) is a disease that is characterized by immune-mediated destruction of CNS myelin. Current MS therapies aim to block peripheral immune cells from entering the CNS. Although these treatments limit new inflammatory activity in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bb47da51fb03e37f22731c6647c70c
https://doi.org/10.4049/jimmunol.1600825
https://doi.org/10.4049/jimmunol.1600825
Autor:
Scott M. Seki, Delaney Liskey, Rebecca M. Beiter, Emily Farber, Megan S Chappell, Christopher C. Overall, David M. Johanson, Suna Onengut-Gumuscu, Jeffrey L. Dupree, Dorian A. Rosen, Anthony Fernandez-Castaneda, Alban Gaultier
Publikováno v:
Acta Neuropathol
Oligodendrocyte progenitor cells (OPCs) account for about 5% of total brain and spinal cord cells, giving rise to myelinating oligodendrocytes that provide electrical insulation to neurons of the CNS. OPCs have also recently been shown to regulate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b3c66f2f8d974c5a97fbcb1d18bff2
https://pubmed.ncbi.nlm.nih.gov/31552482
https://pubmed.ncbi.nlm.nih.gov/31552482
Autor:
Ku-Lung Hsu, Kacper Posyniak, Timothy N. J. Bullock, Charles Spivey, Rebecca M. Beiter, Scott M. Seki, Rebecca L. McCloud, Nikolas William Hayes, Lelisa Gemta, Dorian A. Rosen, Alban Gaultier, Anthony Fernandez-Castaneda
Publikováno v:
SSRN Electronic Journal.
T cells play crucial, and perhaps initiating roles in autoimmune diseases like Multiple Sclerosis (MS). Elucidating the mechanisms that regulate inflammatory T cell responses could reveal novel means of modulation of their pathological role. Small mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1952bb5d6157a45296fb1b1082877e6
https://doi.org/10.2139/ssrn.3363732
https://doi.org/10.2139/ssrn.3363732
Publikováno v:
Family Medicine and Community Health
Family Medicine and Community Health, Vol 8, Iss 1 (2020)
Family Medicine and Community Health, Vol 8, Iss 1 (2020)
It was not so long ago that an attending physician accused me of the following: ‘you’re advocating for the elimination of the physical exam from medicine!’ We were on rounds and debating the objectivity and merit of a single observer non-blinde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb9a9503cbd1314db1c5496b27357b0
https://doi.org/10.1136/fmch-2019-000284
https://doi.org/10.1136/fmch-2019-000284
Autor:
Rebecca M. Beiter, Scott M. Seki, Alban Gaultier, Anthony Fernandez-Castaneda, Dorian A. Rosen, Judith A. Woodfolk, Jacob D. Eccles
Publikováno v:
Science translational medicine. 11(478)
Sepsis is an often-deadly complication of infection in which systemic inflammation damages the vasculature, leading to tissue hypoperfusion and multiple organ failure. Currently, the standard of care for sepsis is predominantly supportive, with few t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c11e1c3378dbaf24bc254e885749f7
https://pubmed.ncbi.nlm.nih.gov/30918112
https://pubmed.ncbi.nlm.nih.gov/30918112
Autor:
Tzu-Ying Chuang, Yong Guo, James Mandell, Scott M. Seki, Claudia F. Lucchinetti, Alban Gaultier, David M. Johanson, Abagail M. Rosen
Publikováno v:
Acta Neuropathologica Communications
Multiple sclerosis is a devastating neurological disorder characterized by the autoimmune destruction of the central nervous system myelin. While T cells are known orchestrators of the immune response leading to MS pathology, the precise contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d737252b6e4ab106f7d2cdd3981867
http://europepmc.org/articles/PMC4940960
http://europepmc.org/articles/PMC4940960
Publikováno v:
Family Medicine and Community Health, Vol 8, Iss 1 (2020)
Externí odkaz:
https://doaj.org/article/45bf982948d34947bbd8c29cecb1749a