Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Scott M. Norberg"'
Autor:
Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin, David F. Stroncek
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Clinical CAR T-cell therapy using integrating vector systems represents a promising approach for the treatment of hematological malignancies. Lentiviral and γ-retroviral vectors are the most commonly used vectors in the manufactu
Externí odkaz:
https://doaj.org/article/32a010a258d84ef0bd9faf982f28cee6
Autor:
Cem Sievers, Yvette Robbins, Ke Bai, Xinping Yang, Paul E. Clavijo, Jay Friedman, Andrew Sinkoe, Scott M. Norberg, Christian Hinrichs, Carter Van Waes, Clint T. Allen
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Cem Sievers et al. performed genomic and transcriptomic analysis in human recurrent respiratory papillomatosis (RRP). They found that RRP harbors few genomic alterations, but that distinct transcriptional subtypes correlate with HPV gene expression a
Externí odkaz:
https://doaj.org/article/171b6a7301b7497492e9d276252d04f7
Autor:
Bridget Marcinkowski, Sanja Stevanović, Sarah R. Helman, Scott M. Norberg, Carylinda Serna, Benjamin Jin, Nikolaos Gkitsas, Tejas Kadakia, Andrew Warner, Jeremy L. Davis, Lisa Rooper, Christian S. Hinrichs
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract T cell receptor (TCR) gene-engineered T cells have shown promise in the treatment of melanoma and synovial cell sarcoma, but their application to epithelial cancers has been limited. The identification of novel therapeutic TCRs for the targe
Externí odkaz:
https://doaj.org/article/bbb4150f15a345daa092a3f920298391
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1 (2019)
BackgroundRecurrent respiratory papillomatosis (RRP) is a human papillomavirus (HPV)-driven disorder that causes substantial morbidity and can lead to fatal distal airway obstruction and post-obstructive pneumonias. Patients require frequent surgical
Externí odkaz:
https://doaj.org/article/f2dbf3e72f274e6ba3f0c673293a3f7f
Autor:
Kenneth Cornetta, Jing Yao, Kimberley House, Lisa Duffy, Prasad S. Adusumilli, Rachel Beyer, Claire Booth, Malcolm Brenner, Kevin Curran, Bambi Grilley, Helen Heslop, Christian S. Hinrichs, Rosandra N. Kaplan, Hans-Peter Kiem, James Kochenderfer, Donald B. Kohn, Sham Mailankody, Scott M. Norberg, Roisin E. O'Cearbhaill, Jennifer Pappas, Jae Park, Carlos Ramos, Antonio Ribas, Isabelle Rivière, Steven A. Rosenberg, Craig Sauter, Nirali N. Shah, Susan F. Slovin, Adrian Thrasher, David A. Williams, Tsai-Yu Lin
Publikováno v:
Molecular Therapy. 31:801-809
The clinical impact of any therapy requires the product be safe and effective. Gammaretroviral vectors pose several unique risks, including inadvertent exposure to replication competent retrovirus (RCR) that can arise during vector manufacture. The U
Autor:
Ke Bai, Scott M. Norberg, Cem Sievers, Tanya Meyer, Jay Friedman, Christian Hinrichs, Clint T. Allen
Publikováno v:
Head & Neck. 44
Publikováno v:
Cancer cell.
Engineered T cell therapy has shown remarkable efficacy in hematologic malignancies and has the potential for application to common epithelial cancers. Diverse T cell therapy strategies including adoptive transfer of tumor-infiltrating lymphocytes, c
Autor:
Alexander H. Yang, Melissa Abel, Anita J. Stokes, Theo Heller, Scott M. Norberg, Louis Y. Korman
Publikováno v:
Gastrointestinal endoscopy. 96(4)
Publikováno v:
Nature Medicine. 28:635-636
Publikováno v:
Otolaryngologic clinics of North America. 54(4)
This article reviews the most recent literature describing clinical advances in adoptive cell therapy for patients with head and neck cancer. Clinical trials with tumor-infiltrating lymphocyte and gene-engineered T-cell receptor T-cell therapy are hi