Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Scott M. Kahn"'
Autor:
Scott M. Kahn
Publikováno v:
Personalized medicine. 11(2)
NGS for Cancer Drug Development 24–26 September 2013, Boston, MA, USA Many of us who, prior to the -omics revolution, staunchly pursued the molecular basis of disease causation recognized the fundamental importance that biomarkers held for the even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841d7087aef48a74c223a0d2ea4504c7
https://pubmed.ncbi.nlm.nih.gov/29751374
https://pubmed.ncbi.nlm.nih.gov/29751374
Publikováno v:
Journal of Endocrinology. 175:113-120
Sex hormone-binding globulin (SHBG) is a multifunctional protein that acts in humans to regulate the response to steroids at several junctures. It was originally described as a hepatically secreted protein that is the major binding protein for sex st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128605c2da2a6e19d61a489cd99840c0
https://doi.org/10.1677/joe.0.1750113
https://doi.org/10.1677/joe.0.1750113
Publikováno v:
Experimental Cell Research. 215:284-293
We previously isolated a partial cDNA sequence, termed TPAR1 (TPA repressed gene 1), from a cDNA library constructed from C3H10T1/2 mouse embryo fibroblasts treated with TPA, using a differential screening procedure. (M.D. Johnson et al. Mol. Cell. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1e0e8ce2ecdf84890ca2f87909699c
https://doi.org/10.1006/excr.1994.1344
https://doi.org/10.1006/excr.1994.1344
Autor:
Wei Jiang, Yu-Jing Zhang, Scott M. Kahn, D B Xu, Kevin R. O'Driscoll, I. B. Weinstein, M A Blackwood, Christoph Borner, Koji Nomoto
Publikováno v:
Carcinogenesis. 15:2919-2925
The amino-terminal regulatory domain portion of each protein kinase C (PKC) family member (which in the case of PKC beta 1 includes the pseudosubstrate, C1, V1 and C2 domains) plays an important role in regulating the kinase activity of the carboxyl-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67427b53bd50856575645b1ebbe8eed4
https://doi.org/10.1093/carcin/15.12.2919
https://doi.org/10.1093/carcin/15.12.2919
Publikováno v:
Journal of Biological Chemistry. 268:3715-3719
Certain isoforms of protein kinase C (PKC) require both Ca2+ and phospholipid for optimum activity. However, little is known about the nature of the interaction between PKC and Ca2+. The present study demonstrates that the isolated regulatory domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::097da569b7802b30eb1d636220027de8
https://doi.org/10.1016/s0021-9258(18)53752-2
https://doi.org/10.1016/s0021-9258(18)53752-2
Publikováno v:
Molecular and cellular endocrinology. 316(1)
Sex hormone-binding globulin (SHBG) was initially described as a plasma protein synthesized in, and secreted by, the liver. It was discovered by its ability to bind certain androgens and estrogens and, for many years, was believed to serve as a trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c752e8ab274c0fea44c97359c180930d
https://pubmed.ncbi.nlm.nih.gov/19698759
https://pubmed.ncbi.nlm.nih.gov/19698759
Autor:
Scott M, Kahn, Yu-Hua, Li, Daniel J, Hryb, Atif M, Nakhla, Nicholas A, Romas, Janice, Cheong, William, Rosner
Publikováno v:
Advances in experimental medicine and biology. 617
Sex hormone-binding globulin (SHBG), a plasma protein that binds androgens and estrogens, also participates in the initial steps of a membrane-based steroid signaling pathway in human prostate and breast. We have recently shown that SHBG is expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ce6640cba1240d7284f498aef17aa18
https://pubmed.ncbi.nlm.nih.gov/18497082
https://pubmed.ncbi.nlm.nih.gov/18497082
Autor:
William Rosner, Scott M. Kahn, Yu-Hua Li, Janice Cheong, Nicholas A. Romas, D J Hryb, Atif M. Nakhla
Publikováno v:
Hormonal Carcinogenesis V ISBN: 9780387690780
Sex hormone-binding globulin (SHBG), a plasma protein that binds androgens and estrogens, also participates in the initial steps of a membrane-based steroid signaling pathway in human prostate and breast. We have recently shown that SHBG is expressed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b66fdc50666808456b9a027b9264d59
https://doi.org/10.1007/978-0-387-69080-3_57
https://doi.org/10.1007/978-0-387-69080-3_57
Autor:
Harold C. Neu, Masami Morotomi, Sadayori Hoshina, Paul LoGerfo, Wei Jian, Scott M. Kahn, I. Bernard Weinstein, Peter H.R. Green, Nai Chin
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 13:473-479
Helicobacter pylori is an organism thought to play an important causative role in gastritis and peptic ulcer diseases. We have designed an RNA dot blot assay for the detection of H. pylori, using as probe a synthetic oligonucleotide complementary to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e04c97de873c820efe42dc4c5a96be
https://doi.org/10.1016/0732-8893(90)90079-b
https://doi.org/10.1016/0732-8893(90)90079-b
Publikováno v:
Hormonal Carcinogenesis IV ISBN: 0387237836
Sex Hormone Binding Globulin (SHBG), in addition to regulating free concentrations of steroid sex hormones in plasma, also participates in membrane-based steroid signaling in breast and prostate cells. In this study, we address whether the breast and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::177701e630d68a19c90a2f89223a7436
https://doi.org/10.1007/0-387-23761-5_56
https://doi.org/10.1007/0-387-23761-5_56