Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Scott M. Jenkins"'
Autor:
Carol J. Burns, Giffe T. Johnson, Stephen E. Graham, Heidi S. Erickson, Judy S. LaKind, Scott M. Jenkins
Publikováno v:
Global Epidemiology, Vol 2, Iss, Pp 100017-(2020)
A Matrix has recently been presented as a tool to assist in the translation of epidemiology literature for the needs of risk assessment. The Matrix is an approach to bridge the epidemiology-risk assessment gap and includes nine risk assessor “asks
Publikováno v:
Air Qual Atmos Health
Epidemiologic studies relating ambient ozone concentrations to adverse health outcomes have typically relied on spatial averages of concentrations from nearby monitoring stations, referred to as “composite monitors.” This practice reflects the as
Publikováno v:
Developmental Brain Research. 151:1-12
Human exposure to the organotins can occur due to their use as polyvinyl chloride heat stabilizers and as marine biocides. The consequences of this exposure for human health are unknown. We initially compared the toxicity of monomethyltin, dimethylti
Autor:
Vann Bennett, Scott M. Jenkins
Publikováno v:
Proceedings of the National Academy of Sciences. 99:2303-2308
Nodes of Ranvier are excitable regions of axonal membranes highly enriched in voltage-gated sodium channels that propagate action potentials. The mechanism of protein clustering at nodes has been a source of controversy. In this study, developmental
Autor:
Gail V.W. Johnson, Scott M. Jenkins
Publikováno v:
Journal of Neurochemistry. 74:1463-1468
Tau is a microtubule-associated protein (MAP) that is functionally modulated by phosphorylation and that is hyperphosphorylated in several neurodegenerative diseases. Because phosphorylation regulates both normal and pathological tau functioning, it
Autor:
Robert Sealock, Anindita Sen, Krishnakumar Kizhatil, Vann Bennett, Scott M. Jenkins, Neal R. Kramarcy
Publikováno v:
Journal of Cell Science. 114:3823-3835
Phosphorylation of neurofascin, a member of the L1 family of cell adhesion molecules (L1 CAMs), at the conserved FIGQY-tyrosine abolishes the ankyrin-neurofascin interaction. This study provides the first evidence, in Drosophila melanogaster and vert
Publikováno v:
Biochemical Journal. 345:263-270
Tau is a microtubule-associated protein that is functionally modulated by phosphorylation and hyperphosphorylated in several neurodegenerative diseases. Because phosphorylation regulates both normal and pathological tau functioning, it is of great in
Autor:
Gail V.W. Johnson, Scott M. Jenkins
Publikováno v:
NeuroReport. 9:67-71
Based on the results of recent in vitro studies, tau has been proposed to be involved in regulating signal transduction through the phospholipase C-gamma (PLC-gamma) signaling pathway. The present study provides support for the physiological relevanc
Autor:
Scott M. Jenkins, Gail V.W. Johnson
Publikováno v:
Brain Research. 767:305-313
This study examined the phosphorylation of tau on Ser 262, within the first microtubule-binding domain, by a developmentally regulated 100 kDa protein kinase exhibiting significantly greater activity in the embryonic rat brain than in the adult rat b
Autor:
Scott M. Jenkins, Gail V.W. Johnson
Publikováno v:
Neuroscience Research Communications. 20:137-146
Although the function of the low-affinity neurotrophin receptor (p75NTR) has not yet been clearly established, there is increasing evidence to suggest that it may play a role in determining cell viability independent of an interaction with Trk recept