Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Scott M. Haake"'
Autor:
Scott M. Haake, Erin J. Plosa, Jonathan A. Kropski, Lindsay A. Venton, Anupama Reddy, Fabian Bock, Betty T. Chang, Allen J. Luna, Kateryna Nabukhotna, Zhi-Qi Xu, Rebecca A. Prather, Sharon Lee, Harikrishna Tanjore, Vasiliy V. Polosukhin, Olga M. Viquez, Angela Jones, Wentian Luo, Matthew H. Wilson, W. Kimryn Rathmell, Pierre P. Massion, Ambra Pozzi, Timothy S. Blackwell, Roy Zent
Publikováno v:
JCI Insight, Vol 7, Iss 15 (2022)
Integrins — the principal extracellular matrix (ECM) receptors of the cell — promote cell adhesion, migration, and proliferation, which are key events for cancer growth and metastasis. To date, most integrin-targeted cancer therapeutics have disr
Externí odkaz:
https://doaj.org/article/265f440d006847c6922cd3a32eff3553
Autor:
Xian-De Liu, Wen Kong, Christine B. Peterson, Daniel J. McGrail, Anh Hoang, Xuesong Zhang, Truong Lam, Patrick G. Pilie, Haifeng Zhu, Kathryn E. Beckermann, Scott M. Haake, Sevinj Isgandrova, Margarita Martinez-Moczygemba, Nidhi Sahni, Nizar M. Tannir, Shiaw-Yih Lin, W. Kimryn Rathmell, Eric Jonasch
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
PBRM1, encoding for a subunit of the SWI/SNF complex, is the second most frequently mutated gene in clear cell renal cell carcinoma (ccRCC). Here, the authors show that PBRM1 loss reduces IFNγ-mediated signalling resulting in a less immunogenic tumo
Externí odkaz:
https://doaj.org/article/2c2ffa7605cd4f008c5d3c780840e07f
Autor:
Christopher G. Wood, James E. Ferguson III, Joel S. Parker, Dominic T. Moore, Jennifer G. Whisenant, Susan J. Maygarden, Eric M. Wallen, William Y. Kim, Mathew I. Milowsky, Kathryn E. Beckermann, Nancy B. Davis, Scott M. Haake, Jose A. Karam, Dante S. Bortone, Benjamin G. Vincent, Thomas Powles, W. Kimryn Rathmell
Publikováno v:
JCI Insight, Vol 5, Iss 22 (2020)
BACKGROUND Surgery remains the frontline therapy for patients with localized clear cell renal cell carcinoma (ccRCC); however, 20%–40% recur. Angiogenesis inhibitors have improved survival in metastatic patients and may result in responses in the n
Externí odkaz:
https://doaj.org/article/514517eaefb4496c854f9e31607be03d
Autor:
Eileen Shiuan, Anupama Reddy, Stephanie O. Dudzinski, Aaron R. Lim, Ayaka Sugiura, Rachel Hongo, Kirsten Young, Xian-De Liu, Christof C. Smith, Jamye O’Neal, Kimberly B. Dahlman, Renee McAlister, Beiru Chen, Kristen Ruma, Nathan Roscoe, Jehovana Bender, Joolz Ward, Ju Young Kim, Christine Vaupel, Jennifer Bordeaux, Shridar Ganesan, Tina M. Mayer, Gregory M. Riedlinger, Benjamin G. Vincent, Nancy B. Davis, Scott M. Haake, Jeffrey C. Rathmell, Eric Jonasch, Brian I. Rini, W. Kimryn Rathmell, Kathryn E. Beckermann
Publikováno v:
Cancers, Vol 13, Iss 6, p 1475 (2021)
Predicting response to ICI therapy among patients with renal cell carcinoma (RCC) has been uniquely challenging. We analyzed patient characteristics and clinical correlates from a retrospective single-site cohort of advanced RCC patients receiving an
Externí odkaz:
https://doaj.org/article/6fcc71df92ae4e88bc109de8c919ec6f
Autor:
Robert Hapke, Lindsay Venton, Kristie Lindsay Rose, Quanhu Sheng, Anupama Reddy, Rebecca Prather, Angela Jones, W. Kimryn Rathmell, Scott M. Haake
Publikováno v:
Kidney Cancer. 6:179-193
BACKGROUND: SET domain-containing protein 2 (SETD2) is commonly mutated in renal cell carcinoma. SETD2 methylates histone H3 as well as a growing list of non-histone proteins. OBJECTIVE: Initially, we sought to explore SETD2-dependent changes in lysi
Autor:
Eric B. Haura, Mayer Fishman, W. Kimryn Rathmell, John M. Koomen, Y. Ann Chen, Julio M. Pow-Sang, Jasreman Dhillon, Roy Zent, Eric A. Welsh, Bin Fang, Fumi Kinose, Yun Bai, Jiannong Li, Scott M. Haake
Supplementary Table 1: Clinical characteristics of patients whose tumors were utilized for phosphotyrosine peptide survey. Supplementary Table 2: Phosphorylated Proteins in RCC Cell Line and Tumor Samples. Supplementary Table 3: Phosphopeptides ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5399c0867b928b6f9090865af1a3125c
https://doi.org/10.1158/1078-0432.22456631.v1
https://doi.org/10.1158/1078-0432.22456631.v1
Autor:
Eric B. Haura, Mayer Fishman, W. Kimryn Rathmell, John M. Koomen, Y. Ann Chen, Julio M. Pow-Sang, Jasreman Dhillon, Roy Zent, Eric A. Welsh, Bin Fang, Fumi Kinose, Yun Bai, Jiannong Li, Scott M. Haake
Supplementary Figures 3-5 Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c455e0681a10f142655be1d5c74ee76
https://doi.org/10.1158/1078-0432.22456637
https://doi.org/10.1158/1078-0432.22456637
Autor:
Eric B. Haura, Mayer Fishman, W. Kimryn Rathmell, John M. Koomen, Y. Ann Chen, Julio M. Pow-Sang, Jasreman Dhillon, Roy Zent, Eric A. Welsh, Bin Fang, Fumi Kinose, Yun Bai, Jiannong Li, Scott M. Haake
Immunohistochemistry demonstrates robust DDR1 phosphorylation in papillary RCC tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9834cd05415c7136d427835f57878d3
https://doi.org/10.1158/1078-0432.22456643
https://doi.org/10.1158/1078-0432.22456643
Autor:
Eric B. Haura, Mayer Fishman, W. Kimryn Rathmell, John M. Koomen, Y. Ann Chen, Julio M. Pow-Sang, Jasreman Dhillon, Roy Zent, Eric A. Welsh, Bin Fang, Fumi Kinose, Yun Bai, Jiannong Li, Scott M. Haake
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbb329f1ef7b815f2943d0d6c040c4a
https://doi.org/10.1158/1078-0432.22456634
https://doi.org/10.1158/1078-0432.22456634
Autor:
Eric B. Haura, Mayer Fishman, W. Kimryn Rathmell, John M. Koomen, Y. Ann Chen, Julio M. Pow-Sang, Jasreman Dhillon, Roy Zent, Eric A. Welsh, Bin Fang, Fumi Kinose, Yun Bai, Jiannong Li, Scott M. Haake
Internal (Supplementary Figure 3) and external (Supplementary Figure 4) tumor LC-MS/MS controls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ff1b9440adf2522dcd5e7dd825d0e9
https://doi.org/10.1158/1078-0432.22456640.v1
https://doi.org/10.1158/1078-0432.22456640.v1