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of 19
pro vyhledávání: '"Scott M. Colles"'
Autor:
Scott M. Colles, Guy M. Chisolm
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 8, Pp 1188-1198 (2000)
Lysophosphatidylcholine (lysoPC), formed during LDL oxidation and located within atherosclerotic plaques, induces numerous cellular responses, but via unknown mechanisms. Cellular events involved in sublethal lysoPC-induced injury were examined becau
Externí odkaz:
https://doaj.org/article/e5f83980955c43d78e711027ee907132
Publikováno v:
Journal of Vascular Surgery. 51:184-193
ObjectiveLimited endothelial cell (EC) coverage and anastomotic intimal hyperplasia contribute to thrombosis and failure of prosthetic grafts. Lipid accumulation and lipid oxidation are associated with decreased EC migration and intimal hyperplasia.
Autor:
Pinaki Chaudhuri, Scott M. Colles, Linda M. Graham, Manjunatha B. Bhat, David R. Van Wagoner, Lutz Birnbaumer
Publikováno v:
Molecular Biology of the Cell. 19:3203-3211
Canonical transient receptor potential (TRPC) channels are opened by classical signal transduction events initiated by receptor activation or depletion of intracellular calcium stores. Here, we report a novel mechanism for opening TRPC channels in wh
Publikováno v:
Trends in Cardiovascular Medicine. 11:131-138
The cell injury caused by oxidized lipoproteins was among the first findings that led to the theory that it is the oxidation of low-density lipoprotein (LDL), not just LDL concentration, that leads to arterial disease. Voluminous studies have now rev
Autor:
Guy M. Chisolm, Scott M. Colles
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 8, Pp 1188-1198 (2000)
Lysophosphatidylcholine (lysoPC), formed during LDL oxidation and located within atherosclerotic plaques, induces numerous cellular responses, but via unknown mechanisms. Cellular events involved in sublethal lysoPC-induced injury were examined becau
Autor:
Yonghong Chen, David Schmitt, Stanley A Hazen, Zhongzhou Shen, Renliang Zhang, Scott M. Colles, Weijia Wu, Guy M. Chisolm, Robert G. Salomon
Publikováno v:
Biochemistry. 38:16904-16915
The initiation of lipid peroxidation and the concomitant formation of biologically active oxidized lipids and sterols is believed to play a central role in the pathogenesis of inflammatory and vascular disorders. Here we explore the role of neutrophi
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1436:413-425
Liver fatty acid binding protein (L-FABP) appears to contain several different forms that may result from post-translational modification or bound ligand. To further assess this possibility, L-FABP was purified from rat liver homogenate and two putat
Roles of multiple oxidized LDL lipids in cellular injury: dominance of 7 beta-hydroperoxycholesterol
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 9, Pp 2018-2028 (1996)
The relative toxicities of several lipid oxidation products formed on oxidized LDL, their presence on oxidized LDL, and potential mechanisms of cell injury compared to oxidized LDL were examined. Toxicities to fibroblasts, with lipoprotein-deficient
Autor:
Sean C. Myers-Payne, Nicolai A. Avdulov, W.G. Wood, Urule Igbavboa, Scott M. Colles, Friedhelm Schroeder, J Joseph
Publikováno v:
Biochemistry. 34:5945-5959
Structural and dielectric alteration by ethanol in vitro and chronic ethanol consumption were examined in synaptic plasma membranes (SPM) using diphenylhexatriene and charged diphenylhexatriene derivatives. These fluorophores, in combination with mul
Publikováno v:
Journal of Vascular Surgery. 49(5)