Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Scott M Emrich"'
Autor:
Scott M Emrich, Ryan E Yoast, Xuexin Zhang, Adam J Fike, Yin-Hu Wang, Kristen N Bricker, Anthony Y Tao, Ping Xin, Vonn Walter, Martin T Johnson, Trayambak Pathak, Adam C Straub, Stefan Feske, Ziaur SM Rahman, Mohamed Trebak
Publikováno v:
eLife, Vol 12 (2023)
The essential role of store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions in B
Externí odkaz:
https://doaj.org/article/5b4624a722da497c9f2661a9b380baec
Autor:
Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin T Johnson, Xuexin Zhang, Ping Xin, Ryan E Yoast, Scott M Emrich, Gregory S Yochum, Israel Sekler, Walter A Koltun, Donald L Gill, Nadine Hempel, Mohamed Trebak
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/bacfc4e9fb7f4dd8bf3716d520a39baf
Autor:
Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin T Johnson, Xuexin Zhang, Ping Xin, Ryan E Yoast, Scott M Emrich, Gregory S Yochum, Israel Sekler, Walter A Koltun, Donald L Gill, Nadine Hempel, Mohamed Trebak
Publikováno v:
eLife, Vol 9 (2020)
Despite the established role of mitochondria in cancer, the mechanisms by which mitochondrial Ca2+ (mtCa2+) regulates tumorigenesis remain incompletely understood. The crucial role of mtCa2+ in tumorigenesis is highlighted by altered expression of pr
Externí odkaz:
https://doaj.org/article/5281232761db416a876d72cbe79942a1
Autor:
Ryan E. Yoast, Scott M. Emrich, Xuexin Zhang, Ping Xin, Martin T. Johnson, Adam J. Fike, Vonn Walter, Nadine Hempel, David I. Yule, James Sneyd, Donald L. Gill, Mohamed Trebak
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The essential role of ORAI1 channels in receptor-evoked Ca2+ signaling is well understood, but the roles of ORAI2 and ORAI3 remained obscure. Here authors show that ORAI2 and ORAI3 channels multimerize with ORAI1 to expand the range of sensitivity of
Externí odkaz:
https://doaj.org/article/d0bad2674967414e8be76ad70168e97d
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100618- (2021)
Summary: This protocol outlines steps to visualize and detect Ca2+ puffs following photo-liberation of caged inositol-1,4,5-trisphosphate (IP3) from HEK-293 cells expressing only the native IP3R type 1 receptor using total internal reflection fluores
Externí odkaz:
https://doaj.org/article/7f29c59e981a4bf091e83d08bbde2cca
Autor:
Scott M Emrich, Ryan E Yoast, Xuexin Zhang, Adam J Fike, Yin-Hu Wang, Kristen N Bricker, Anthony Y Tao, Ping Xin, Vonn Walter, Martin T Johnson, Trayambak Pathak, Adam C Straub, Stefan Feske, Ziaur SM Rahman, Mohamed Trebak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6949a79f1dcda70f27e94b25331860
https://doi.org/10.7554/elife.84708.sa2
https://doi.org/10.7554/elife.84708.sa2
Publikováno v:
Journal of Surgical Research. 267:527-535
Background Inflammation of diverticula, which are outpouchings of the colonic bowl wall, causes diverticulitis. Severe cases of diverticulitis require surgical intervention. Through RNA-seq analysis of intestinal tissues, we previously found that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53ba70577d7cf32ec32b4967f39419df
https://doi.org/10.1016/j.jss.2021.06.016
https://doi.org/10.1016/j.jss.2021.06.016
Autor:
Scott M. Emrich, Ryan E. Yoast, Xuexin Zhang, Adam J. Fike, Yin-Hu Wang, Kristen N. Bricker, Anthony Tao, Ping Xin, Vonn Walter, Martin T. Johnson, Trayambak Pathak, Adam C. Straub, Stefan Feske, Ziaur S.M. Rahman, Mohamed Trebak
The essential role of store-operated Ca2+ entry (SOCE) through Ca2+ release-activated Ca2+ (CRAC) channels in T cells is well established. In contrast, the contribution of individual Orai isoforms to SOCE and their downstream signaling functions in B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e396a01d7ac2ecf4a599e7218f0ccbf
https://doi.org/10.1101/2022.05.06.490918
https://doi.org/10.1101/2022.05.06.490918
Autor:
Aparna Gudlur, Robert M. Nwokonko, Ryan E. Yoast, Mohamed Trebak, Nadine Hempel, Donald L. Gill, Martin Johnson, Scott M. Emrich, Ping Xin, Xuexin Zhang, Patrick G. Hogan, Raphael Jean Courjaret, Khaled Machaca, Wei Li
Publikováno v:
Proceedings of the National Academy of Sciences. 117:17369-17380
Voltage-gated L-type Ca2+ channel (Cav1.2) blockers (LCCBs) are major drugs for treating hypertension, the preeminent risk factor for heart failure. Vascular smooth muscle cell (VSMC) remodeling is a pathological hallmark of chronic hypertension. VSM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c41bb9e7240902f70e858f7fce582cb
https://doi.org/10.1073/pnas.2007598117
https://doi.org/10.1073/pnas.2007598117
Autor:
Nadine Hempel, David I. Yule, Ping Xin, James Sneyd, Ryan E. Yoast, Adam J. Fike, Mohamed Trebak, Scott M. Emrich, Vonn Walter, Martin Johnson, Xuexin Zhang, Donald L. Gill
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The essential role of ORAI1 channels in receptor-evoked Ca2+ signaling is well understood, yet little is known about the physiological activation of the ORAI channel trio natively expressed in all cells. The roles of ORAI2 and ORAI3 have remained obs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2eed8dfccc3933f8d5cd1ec1ac7c195
https://doaj.org/article/d0bad2674967414e8be76ad70168e97d
https://doaj.org/article/d0bad2674967414e8be76ad70168e97d