Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Scott M Dyck"'
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 12, Pp 2080-2082 (2018)
Externí odkaz:
https://doaj.org/article/4222f5104edc4e53b91a57fe1bf063fc
Autor:
Soheila Karimi-Abdolrezaee, Scott M. Dyck, Hardeep Kataria, Jerry Silver, Khashayar Akbari-Kelachayeh
Publikováno v:
Glia. 67:125-145
Following spinal cord injury (SCI), the population of mature oligodendrocytes undergoes substantial cell death; promoting their preservation and replacement is a viable strategy for preserving axonal integrity and white matter repair in the injured s
Autor:
Soheila Karimi-Abdolrezaee, Arsalan Alizadeh, Hardeep Kataria, Scott M. Dyck, Kallivalappil T. Santhosh, Ghazaleh M. Shahriary, Dung H. Nguyen
Publikováno v:
Glia. 65:1152-1175
Spinal cord injury (SCI) results in glial activation and neuroinflammation, which play pivotal roles in the secondary injury mechanisms with both pro- and antiregeneration effects. Presently, little is known about the endogenous molecular mechanisms
Autor:
Eftekhar Eftekharpour, Soheila Karimi-Abdolrezaee, Christopher G. Hart, James A. Thliveris, Pandian Nagakannan, Arsalan Alizadeh, Scott M. Dyck, Hardeep Kataria
Publikováno v:
Experimental neurology. 325
Traumatic spinal cord injury (SCI) elicits a cascade of secondary injury mechanisms that induce profound changes in glia and neurons resulting in their activation, injury or cell death. The resultant imbalanced microenvironment of acute SCI also nega
Publikováno v:
Frontiers in Neurology
Frontiers in Neurology, Vol 10 (2019)
Frontiers in Neurology, Vol 10 (2019)
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial socioeconomic implications for patients and their care-givers. Recent advances in medical management of SCI has significantly improved diagnosis, stabilizat
Autor:
Arsalan Alizadeh, Hardeep Kataria, Jerry Silver, Soheila Karimi-Abdolrezaee, Scott M. Dyck, Bradley T. Lang, Kallivalappil T. Santhosh
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-26 (2018)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Traumatic spinal cord injury (SCI) results in upregulation of chondroitin sulfate proteoglycans (CSPGs) by reactive glia that impedes repair and regeneration in the spinal cord. Degradation of CSPGs is known to be beneficial in promoting e
Autor:
Scott M. Dyck, Soheila Karimi-Abdolrezaee, Evan H. Proulx, Arsalan Alizadeh, Chia-Lun Wu, Kallivalappil T. Santhosh
Publikováno v:
Stem Cells. 33:2550-2563
Multipotent adult neural precursor cells (NPCs) have tremendous intrinsic potential to repair the damaged spinal cord. However, evidence shows that the regenerative capabilities of endogenous and transplanted NPCs are limited in the microenvironment
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Injury to the central nervous system (CNS) results in oligodendrocyte cell death and progressive demyelination. Demyelinated axons undergo considerable physiological changes and molecular reorganizations that collectively result in axonal dysfunction
Publikováno v:
Experimental neurology. 269
Chondroitin Sulfate Proteoglycans (CSPGs) are a major component of the extracellular matrix in the central nervous system (CNS) and play critical role in the development and pathophysiology of the brain and spinal cord. Developmentally, CSPGs provide
Autor:
Jared M. Cregg, Scott M. Dyck, Soheila Karimi-Abdolrezaee, Yi Lan Weng, Yingjie Shen, Marc A. DePaul, Amanda Phuong Tran, Bradley T. Lang, Benjamin P. Brown, Shuxin Li, Jerry Silver, Kui Xu, Sarah A. Busch, Kathryn M. Madalena
Publikováno v:
Nature. 518(7539)
Contusive spinal cord injury leads to a variety of disabilities owing to limited neuronal regeneration and functional plasticity. It is well established that an upregulation of glial-derived chondroitin sulphate proteoglycans (CSPGs) within the glial