Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Scott Lien"'
Autor:
John Wright, Stephanie Lheureux, Ilaria Colombo, Ramy Gadalla, Pamela S Ohashi, Xuan Li, Lisa Wang, Matthew S Block, David G Brooks, Andrea Jewell, Carolyn McCourt, Eugenia Girda, Sarah Temkin, Gini F Fleming, Linda Duska, Daniela E Matei, Panagiotis A Konstantinopoulos, Ben X Wang, Stephanie L Gaillard, Michael McHale, Floor J Backes, Theresa L Werner, Siobhan Kehoe, Rachel Wildman, Shirin Soleimani, Scott Lien, Trevor Pugh
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Combining immunotherapy and antiangiogenic agents is a promising treatment strategy in endometrial cancer. To date, no biomarkers for response have been identified and data on post-immunotherapy progression are lacking. We explored the com
Externí odkaz:
https://doaj.org/article/0e5bfe1cd7414e458e3cfe2d6fbf3f50
Autor:
Stephanie Lheureux, Daniela E Matei, Panagiotis A Konstantinopoulos, Ben X Wang, Ramy Gadalla, Matthew S Block, Andrea Jewell, Stephanie L Gaillard, Michael McHale, Carolyn McCourt, Sarah Temkin, Eugenia Girda, Floor J Backes, Theresa L Werner, Linda Duska, Siobhan Kehoe, Ilaria Colombo, Lisa Wang, Xuan Li, Rachel Wildman, Shirin Soleimani, Scott Lien, John Wright, Trevor Pugh, Pamela S Ohashi, David G Brooks, Gini F Fleming
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004233
BackgroundCombining immunotherapy and antiangiogenic agents is a promising treatment strategy in endometrial cancer. To date, no biomarkers for response have been identified and data on post-immunotherapy progression are lacking. We explored the comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9fcce9f1b96d22b59c8aa1748bb4f7
https://doi.org/10.1136/jitc-2021-004233
https://doi.org/10.1136/jitc-2021-004233
Autor:
Peter Axerio-Cilies, Paul S. Rennie, Takeshi Yamazaki, Ari Kim, Miriam S. Butler, Sam Lawn, Michael E. Cox, Yubin Guo, Fariba Ghaidi, Scott Lien, Mannan Nouri, Marta Mroczek, Lawrence P. McIntosh, Cheryl Y. Gregory-Evans, Artem Cherkasov, Martin E. Gleave, Kush Dalal, Mani Roshan-Moniri, Desmond K. W. Lau, Paul M. Yen, Michael Hsing, Clement Yau
Publikováno v:
Oncotarget
// Miriam S. Butler 1, *, # , Mani Roshan-Moniri 1, *, # , Michael Hsing 1, *, # , Desmond Lau 2, *, # , Ari Kim 1 , Paul Yen 1 , Marta Mroczek 1 , Mannan Nouri 1 , Scott Lien 1 , Peter Axerio-Cilies 1 , Kush Dalal 1 , Clement Yau 1 , Fariba Ghaidi 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c1afad7acff7c115719c3c6e99761b
https://doi.org/10.18632/oncotarget.17124
https://doi.org/10.18632/oncotarget.17124
Autor:
Ben X Wang, Amanda Giesler, Christine Elser, Hal K. Berman, Lillian L. Siu, Marcus O. Butler, Philippe L. Bedard, Zachary William Neil Veitch, Sevan Hakgor, Scott Lien, Eitan Amir, Cindy Yang, Trevor J. Pugh, Pamela S. Ohashi, Sawako Elston, David W. Cescon
Publikováno v:
Journal of Clinical Oncology. 36:1094-1094
1094Background: Pembro is a PD-1 immune checkpoint inhibitor with a low response rate in pretreated mTNBC. In this biomarker driven, investigator-initiated trial we evaluate changes in immune and g...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b7a51287db383690a14bb0b0ec3085a
https://doi.org/10.1200/jco.2018.36.15_suppl.1094
https://doi.org/10.1200/jco.2018.36.15_suppl.1094
Autor:
Haiyan Jiang, Scott Lien, Marcus O. Butler, David Hogg, Cindy Yang, Sawako Elston, Lillian L. Siu, Anna Spreafico, Pamela S. Ohashi, Trevor J. Pugh, Derek L. Clouthier, Yada Kanjanapan
Publikováno v:
Journal of Clinical Oncology. 36:184-184
184 Background: Predictive biomarkers for PEM in MM is an active area of research. Methods: INSPIRE (NCT02644369) is a biomarker-driven Princess Margaret Cancer Centre initiative to evaluate genomic and immunologic changes in tumor and blood of patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e254b9df649473e61fdbb66436c5fc0
https://doi.org/10.1200/jco.2018.36.5_suppl.184
https://doi.org/10.1200/jco.2018.36.5_suppl.184
Autor:
Fariba Ghaidi, Miriam S. Butler, Paul S. Rennie, Kush Dalal, Takeshi Yamazaki, Michael Hsing, Yubin Guo, Mannan Nouri, Artem Cherkasov, Mani Roshan-Moniri, Michael E. Cox, Lawrence P. McIntosh, Sam Lawn, Ari Kim, Martin E. Gleave, Cheryl Y. Gregory-Evans, Scott Lien, Marta Mroczek, Peter Axerio-Cilies, Desmond K. W. Lau, Clement Yau, Paul M. Yen
Publikováno v:
Cancer Research. 77:130-130
Genomic alterations involving translocations of the ETS-related gene ERG occur in approximately half of prostate cancer cases. These alterations result in aberrant, androgen-regulated production of ERG protein variants that directly contribute to dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e57ee42d0139eda58e4b62ab2f9c9f36
https://doi.org/10.1158/1538-7445.am2017-130
https://doi.org/10.1158/1538-7445.am2017-130
Autor:
Helen Chow, Amanda Giesler, Stephanie Lheureux, Cindy Yang, Daphne Day, Marcus O. Butler, Aaron R. Hansen, Albiruni Ryan Abdul Razak, Diana Gray, Sawako Kobori, Lillian L. Siu, Philippe L. Bedard, Anna Spreafico, Pamela S. Ohashi, Jeremy Lewin, Ilaria Colombo, Derek L. Clouthier, Trevor J. Pugh, Scott Lien
Publikováno v:
Journal of Clinical Oncology. 35:11607-11607
11607 Background: Validated biomarkers of response to immune checkpoint inhibitors are needed. Methods: INSPIRE (NCT02644369) is a biomarker-driven study to comprehensively evaluate changes in genomic and immune landscapes in tumors and blood of pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88673adadaab6698337f64bbe8ecb3b3
https://doi.org/10.1200/jco.2017.35.15_suppl.11607
https://doi.org/10.1200/jco.2017.35.15_suppl.11607
Autor:
Cindy Yang, Yada Kanjanapan, Ilaria Colombo, Trevor J. Pugh, Marcus O. Butler, Amit M. Oza, Judy Quintos, Pamela S. Ohashi, Derek L. Clouthier, Luisa Bonilla, Lillian L. Siu, Yeh Chen Lee, Sunu Cyriac, Stephanie Lheureux, Scott Lien, Helen Chow, Neesha C. Dhani, Josee-Lyne Ethier, Victoria Mandilaras
Publikováno v:
Journal of Clinical Oncology. 35:5581-5581
5581 Background: Checkpoint inhibitors have shown to be effective in different tumors and are under investigation in HGSOC. Methods: INSPIRE (NCT02644369) is a prospective multi-cohort study investigating tumor genomic and immune landscapes in pts tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26d4d61ec9f35ca71798e43ac246f30
https://doi.org/10.1200/jco.2017.35.15_suppl.5581
https://doi.org/10.1200/jco.2017.35.15_suppl.5581
Autor:
Scott Lien
Publikováno v:
Social Service Review. 73:128-133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0aa4479ccffa097bb769d0f8f3e6792
https://doi.org/10.1086/515791
https://doi.org/10.1086/515791
Autor:
Huifang Li, Ari Kim, Michael E. Cox, Yubin Guo, Paul S. Rennie, Eric Leblanc, Fariba Ghaidi, Fuqiang Ban, Lawrence P. McIntosh, Michael Hsing, Peter Axerio-Cilies, Desmond K. W. Lau, Miriam S. Butler, Paul M. Yen, Marta Mroczek, Dennis Ma, Scott Lien, Artem Cherkasov, Mani Roshan-Moniri
Publikováno v:
Cancer Research. 75:1652-1652
Prostate cancer (PCa) is one of the leading causes of cancer-related death in men worldwide. The common treatment option for recurring and advanced PCa focuses on inhibiting the androgen receptor (AR). Unfortunately, despite an initial response to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76841ccdb818153198c3ed5adf12d77c
https://doi.org/10.1158/1538-7445.am2015-1652
https://doi.org/10.1158/1538-7445.am2015-1652