Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Scott Lew"'
Publikováno v:
Chest. 160(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a302114bb375a17ccb6da1f2c18d47f
https://pubmed.ncbi.nlm.nih.gov/34366036
https://pubmed.ncbi.nlm.nih.gov/34366036
Publikováno v:
Frontiers in Education, Vol 9 (2024)
IntroductionThe Strengths and Difficulties Questionnaire (SDQ) is one the most widely used behavior screening tools for public schools due to its strong psychometric properties, low cost, and brief (25-question) format. However, this screening tool h
Externí odkaz:
https://doaj.org/article/3a33b3f6abfc4505b70063fd567a8edf
Akademický článek
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Publikováno v:
Protein Science. 25:898-904
In vitro protein stability studies are commonly conducted via thermal or chemical denaturation/renaturation of protein. Conventional data analyses on the protein unfolding/(re)folding require well-defined pre- and post-transition baselines to evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::104319b7008067a06857c3eb04f972fa
https://doi.org/10.1002/pro.2878
https://doi.org/10.1002/pro.2878
Autor:
Scott Lew, Farhad Forouhar, Renate Kirschner-Schwabe, Adolfo A. Ferrando, Jayaraman Seetharaman, Chelsea L. Dieck, Gannie Tzoneva, Liang Tong, Zachary Carpenter, Marta Sanchez-Martin, Alberto Ambesi-Impiombato
Summary Activating mutations in the cytosolic 5′-nucleotidase II gene NT5C2 drive resistance to 6-mercaptopurine in acute lymphoblastic leukemia. Here we demonstrate that constitutively active NT5C2 mutations K359Q and L375F reconfigure the catalyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9800079d9aa4f2773490256c3b2490b8
https://europepmc.org/articles/PMC6049837/
https://europepmc.org/articles/PMC6049837/
Autor:
Bharath Srinivasan, Liang Tong, Lei Mao, Hemalatha Balaram, Gaetano T. Montelione, Mariam Abashidze, John Everett, Scott Lew, Farhad Forouhar, Jayaraman Seetharaman, Chethana Sampangi, Rong Xiao, Arpit Shukla, Sonia Kulkarni, Thomas Acton
Publikováno v:
FEBS Journal. 281:1613-1628
Cytosolic nucleotidase II (cN-II) from Legionella pneumophila (Lp) catalyzes the hydrolysis of GMP and dGMP displaying sigmoidal curves, whereas catalysis of IMP hydrolysis displayed a biphasic curve in the initial rate versus substrate concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd265561c6c7baca1ce619d8a61719fb
https://doi.org/10.1111/febs.12727
https://doi.org/10.1111/febs.12727
Autor:
Farhad Forouhar, Vikram Khipple Mulligan, Jeremy H. Mills, Sagar D. Khare, David Baker, Jayaraman Seetharaman, Jill M. Bolduc, Scott Lew, Barry L. Stoddard, Liang Tong
Publikováno v:
ResearcherID
Genetically encoded unnatural amino acids could facilitate the design of proteins and enzymes of novel function, but correctly specifying sites of incorporation and the identities and orientations of surrounding residues represents a formidable chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4174d6e26df54506f884df0d575c5b9
https://doi.org/10.1021/ja403503m
https://doi.org/10.1021/ja403503m
Autor:
Alexander P. Kuzin, Devin J. Noblin, Thomas Acton, Craig M. Crews, Liang Tong, G. Kornhaber, Gaetano T. Montelione, Scott Lew, Jayaraman Seetharaman, Taavi K. Neklesa, Rong Xiao
Publikováno v:
ACS Chemical Biology. 8:2293-2300
Small molecule control of intracellular protein levels allows temporal and dose-dependent regulation of protein function. Recently, we developed a method to degrade proteins fused to a mutant dehalogenase (HaloTag2) using small molecule hydrophobic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a0d0faaf690fbb988c268e92152d156
https://doi.org/10.1021/cb400569k
https://doi.org/10.1021/cb400569k
Autor:
Bing Yu Chiang, YongQiang Wang, Munif Hussain, Sung Mi Kim, Shay Karkashon, Farhad Forouhar, Syun Ru Yeh, Liang Tong, Scott Lew, Ariel Lewis-Ballester, Maria Almira Correia, Jayaraman Seetharaman, Dipanwita Batabyal
Publikováno v:
Scientific Reports
Tryptophan 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO) play a central role in tryptophan metabolism and are involved in many cellular and disease processes. Here we report the crystal structure of human TDO (hTDO) in a ternary complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf0dd2a1f7e8953562fc6cfa9118b27
http://europepmc.org/articles/PMC5071832
http://europepmc.org/articles/PMC5071832
Autor:
Farhad Forouhar, Rong Xiao, Thomas Acton, Yunhuang Yang, H. Lee, Shuisong Ni, John Everett, Michael A. Kennedy, Sarah Unser, Theresa Ramelot, John F. Hunt, Paolo Rossi, Gaetano T. Montelione, James H. Prestegard, Jayaraman Seetharaman, Scott Lew
Publikováno v:
Biochemistry. 51:7239-7249
The solution nuclear magnetic resonance (NMR) structures and backbone (15)N dynamics of the specialized acyl carrier protein (ACP), RpAcpXL, from Rhodopseudomonas palustris, in both the apo form and holo form modified by covalent attachment of 4'-pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1d52f614d2071ae15ace11281953125
https://doi.org/10.1021/bi300546b
https://doi.org/10.1021/bi300546b