Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Scott L Nuismer"'
Publikováno v:
Expert Review of Vaccines, Vol 23, Iss 1, Pp 294-302 (2024)
ABSTRACTIntroduction Transmissible vaccines offer a novel approach to suppressing viruses in wildlife populations, with possible applications against viruses that infect humans as zoonoses – Lassa, Ebola, rabies. To ensure safety, current designs p
Externí odkaz:
https://doaj.org/article/075be305be1f4726bacb274ec1c03dc7
Autor:
Scott L Nuismer, Andrew J Basinski, Courtney L Schreiner, Evan A Eskew, Elisabeth Fichet-Calvet, Christopher H Remien
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 8, p e1012358 (2024)
Reducing spillover of zoonotic pathogens is an appealing approach to preventing human disease and minimizing the risk of future epidemics and pandemics. Although the immediate human health benefit of reducing spillover is clear, over time, spillover
Externí odkaz:
https://doaj.org/article/e8513ed5d3cd49b2bc243a03facbf72f
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 8, p e0011018 (2023)
Zoonotic pathogens spread by wildlife continue to spill into human populations and threaten human lives. A potential way to reduce this threat is by vaccinating wildlife species that harbor pathogens that are infectious to humans. Unfortunately, even
Externí odkaz:
https://doaj.org/article/d81ef6fef124461c80da919943cc6bad
Autor:
Scott L Nuismer
Publikováno v:
PLoS Biology, Vol 20, Iss 4, p e3001607 (2022)
A recent study in PLOS Biology shows that a betaherpesvirus circulating with the vampire bat, Desmodus rotundus, could serve as an effective vector for a transmissible vaccine capable of reducing the risk of rabies virus spillover in Peru.
Externí odkaz:
https://doaj.org/article/87ef27d0825f4ff8bd346e823d8fa708
Autor:
Andrew J Basinski, Elisabeth Fichet-Calvet, Anna R Sjodin, Tanner J Varrelman, Christopher H Remien, Nathan C Layman, Brian H Bird, David J Wolking, Corina Monagin, Bruno M Ghersi, Peter A Barry, Michael A Jarvis, Paul E Gessler, Scott L Nuismer
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 3, p e1008811 (2021)
Forecasting the risk of pathogen spillover from reservoir populations of wild or domestic animals is essential for the effective deployment of interventions such as wildlife vaccination or culling. Due to the sporadic nature of spillover events and l
Externí odkaz:
https://doaj.org/article/7ff863328a4648d8b87a29355a84ce6c
Autor:
Scott L Nuismer, Christopher H Remien, Andrew J Basinski, Tanner Varrelman, Nathan Layman, Kyle Rosenke, Brian Bird, Michael Jarvis, Peter Barry, Patrick W Hanley, Elisabeth Fichet-Calvet
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0007920 (2020)
Lassa virus is a significant burden on human health throughout its endemic region in West Africa, with most human infections the result of spillover from the primary rodent reservoir of the virus, the natal multimammate mouse, M. natalensis. Here we
Externí odkaz:
https://doaj.org/article/05aae84dc3084d4e8da061756aece8e5
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 7, p e1006857 (2019)
Replicating recombinant vector vaccines consist of a fully competent viral vector backbone engineered to express an antigen from a foreign transgene. From the perspective of viral replication, the transgene is not only dispensable but may even be det
Externí odkaz:
https://doaj.org/article/2ff02c3934f74ff88a8bd010d1d91a1c
Autor:
Scott L Nuismer, Bob Week
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 4, p e1006988 (2019)
Exaggerated traits involved in species interactions have long captivated the imagination of evolutionary biologists and inspired the durable metaphor of the coevolutionary arms race. Despite decades of research, however, we have only a handful of exa
Externí odkaz:
https://doaj.org/article/a15ffe45e138448a8657e987805dbd91
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007251 (2019)
Zoonotic pathogens such as Ebola and rabies pose a major health risk to humans. One proven approach to minimizing the impact of a pathogen relies on reducing its prevalence within animal reservoir populations using mass vaccination. However, two majo
Externí odkaz:
https://doaj.org/article/4f6bcfe0911240ef82004778da488033
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196978 (2018)
As the density of human and domestic animal populations increases, the threat of localized epidemics and global pandemics grows. Although effective vaccines have been developed for a number of threatening pathogens, manufacturing and disseminating va
Externí odkaz:
https://doaj.org/article/04df7ae23fd344869f1f2c90cbb03065