Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Scott L Letendre"'
Autor:
Michelli F Oliveira, Antoine Chaillon, Masato Nakazawa, Milenka Vargas, Scott L Letendre, Matthew C Strain, Ronald J Ellis, Sheldon Morris, Susan J Little, Davey M Smith, Sara Gianella
Publikováno v:
PLoS Pathogens, Vol 13, Iss 1, p e1006112 (2017)
Even when antiretroviral therapy (ART) is started early after infection, HIV DNA might persist in the central nervous system (CNS), possibly contributing to inflammation, brain damage and neurocognitive impairment. Paired blood and cerebrospinal flui
Externí odkaz:
https://doaj.org/article/e64e0181545249f8899dc1b0e0bd5b36
Autor:
Walter Royal, Mariana Cherner, Tricia H Burdo, Anya Umlauf, Scott L Letendre, Jibreel Jumare, Alash'le Abimiku, Peter Alabi, Nura Alkali, Sunday Bwala, Kanayo Okwuasaba, Lindsay M Eyzaguirre, Christopher Akolo, Ming Guo, Kenneth C Williams, William A Blattner
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147182 (2016)
The potential role of gender in the occurrence of HIV-related neurocognitive impairment (NCI) and associations with markers of HIV-related immune activity has not been previously examined. In this study 149 antiretroviral-naïve seropositive subjects
Externí odkaz:
https://doaj.org/article/7ae0f25da6af40728cee74ad3be2da48
Autor:
Arvid Edén, Thomas D Marcotte, Robert K Heaton, Staffan Nilsson, Henrik Zetterberg, Dietmar Fuchs, Donald Franklin, Richard W Price, Igor Grant, Scott L Letendre, Magnus Gisslén
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157160 (2016)
OBJECTIVE:Although milder forms of HIV-associated neurocognitive disorder (HAND) remain prevalent, a correlation to neuronal injury has not been established in patients on antiretroviral therapy (ART). We examined the relationship between mild HAND a
Externí odkaz:
https://doaj.org/article/76e001bde3664fa9963c57abd598f660
Autor:
Giulio Barteselli, Jay Chhablani, Maria Laura Gomez, Aubrey L Doede, Laurie Dustin, Igor Kozak, Dirk-Uwe Bartsch, Stanley P Azen, Scott L Letendre, William R Freeman
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97023 (2014)
Visual function abnormalities are common in people living with HIV disease (PLWH) without retinitis, even after improvement in immune status. Abnormalities such as reduced contrast sensitivity, altered color vision, peripheral visual field loss, and
Externí odkaz:
https://doaj.org/article/4ea4120adce040958464f2cb6787a602
Autor:
Zhan Zhang, Monica D. Reece, Sebastian Roa, William Tyor, Donald R. Franklin, Scott L. Letendre, Vincent C. Marconi, Albert M. Anderson, Christina Gavegnano
Publikováno v:
Neurotherapeutics, Vol 21, Iss 4, Pp e00373- (2024)
We evaluated the HIV-1 DNA reservoir in peripheral blood mononuclear cells (PBMC) and cerebrospinal fluid (CSF) in people with HIV (PWH) and associations to cognitive dysfunction. Using the intact proviral DNA assay (IPDA), an emerging technique to i
Externí odkaz:
https://doaj.org/article/23540f51113e405594b36be75966886a
Autor:
David J Moore, Mollie J P Roediger, Lynn E Eberly, Kaitlin Blackstone, Braden Hale, Amy Weintrob, Anuradha Ganesan, Brian K Agan, Scott L Letendre, Nancy F Crum-Cianflone
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47310 (2012)
HIV-associated neurocognitive disorders (HAND) remain prevalent despite improved antiretroviral treatment (ART), and it is essential to have a sensitive and specific HAND screening tool.Participants were 200 HIV-infected US military beneficiaries, ma
Externí odkaz:
https://doaj.org/article/b1cc4c8754814494bbde39e9c5b9a24f
Autor:
Mohammadsobhan Sheikh Andalibi, Jerel Adam Fields, Jennifer E. Iudicello, Monica M. Diaz, Bin Tang, Scott L. Letendre, Ronald J. Ellis
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4245 (2024)
Distal sensory polyneuropathy (DSP) is a disabling, chronic condition in people with HIV (PWH), even those with viral suppression of antiretroviral therapy (ART), and with a wide range of complications, such as reduced quality of life. Previous studi
Externí odkaz:
https://doaj.org/article/39eea6e0a8814efc82e1043987a7a71e
Autor:
Igor Grant, Evgeny Krupitsky, Marina Vetrova, Anya Umlauf, Robert K. Heaton, Richard L. Hauger, Olga Toussova, Donald R. Franklin, Scott L. Letendre, George Woody, Elena Blokhina, Dmitry Lioznov, Edwin Zvartau
Publikováno v:
Viruses, Vol 16, Iss 1, p 92 (2024)
Objective: Many persons with opioid use disorders (OUDs) have HIV disease and experience clinically significant stress after they enroll in abstinence-based treatment and undergo medically assisted withdrawal. We examined whether opioid withdrawal af
Externí odkaz:
https://doaj.org/article/0ee98b29a60744b4916797fb61c4e809
Autor:
Patricia K. Riggs, Albert M. Anderson, Bin Tang, Leah H. Rubin, Susan Morgello, Christina M. Marra, Benjamin B. Gelman, David B. Clifford, Donald Franklin, Robert K. Heaton, Ronald J. Ellis, Christine Fennema-Notestine, Scott L. Letendre
Publikováno v:
Viruses, Vol 15, Iss 12, p 2410 (2023)
Structural brain abnormalities, including those in white matter (WM), remain common in people with HIV (PWH). Their pathogenesis is uncertain and may reflect multiple etiologies. Oxidative stress is associated with inflammation, HIV, and its comorbid
Externí odkaz:
https://doaj.org/article/674144d9abd54ab9bbe9c396f0f14767
Twelve-year neurocognitive decline in HIV is associated with comorbidities, not age: a CHARTER study
Autor:
Robert K Heaton, Ronald J Ellis, Bin Tang, Christina M Marra, Leah H Rubin, David B Clifford, J Allen McCutchan, Benjamin B Gelman, Susan Morgello, Donald R Franklin, Scott L Letendre
Publikováno v:
Brain : a journal of neurology, vol 146, iss 3
Brain
Brain
Modern antiretroviral therapy (ART) has increased longevity of people with HIV and shifted the age distribution of the HIV pandemic upward toward that of the general population. This positive development has also led to concerns about premature and/o