Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Scott Kuersten"'
Autor:
Asako Tan, Senthil Murugapiran, Alaya Mikalauskas, Jeff Koble, Drew Kennedy, Fred Hyde, Victor Ruotti, Emily Law, Jordan Jensen, Gary P. Schroth, Jean M. Macklaim, Scott Kuersten, Brice LeFrançois, Daryl M. Gohl
Publikováno v:
BMC Microbiology, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract The microbiota that colonize the human gut and other tissues are dynamic, varying both in composition and functional state between individuals and over time. Gene expression measurements can provide insights into microbiome composition and f
Externí odkaz:
https://doaj.org/article/4eb70698f25f4d8a8f6a55e39aaa7355
Autor:
Bert Dhondt, Cláudio Pinheiro, Edward Geeurickx, Joeri Tulkens, Glenn Vergauwen, Edwin Van Der Pol, Rienk Nieuwland, Anneleen Decock, Ilkka Miinalainen, Pekka Rappu, Gary Schroth, Scott Kuersten, Jo Vandesompele, Pieter Mestdagh, Nicolaas Lumen, Olivier De Wever, An Hendrix
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 5, Pp n/a-n/a (2023)
Abstract The analysis of extracellular vesicles (EV) in blood samples is under intense investigation and holds the potential to deliver clinically meaningful biomarkers for health and disease. Technical variation must be minimized to confidently asse
Externí odkaz:
https://doaj.org/article/88cf6c37fc744c8b910af6ec08d4058f
Autor:
Eva Hulstaert, Anneleen Decock, Annelien Morlion, Celine Everaert, Kimberly Verniers, Justine Nuytens, Nele Nijs, Gary P. Schroth, Scott Kuersten, Stephen M. Gross, Pieter Mestdagh, Jo Vandesompele
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100475- (2021)
Summary: Comprehensive transcriptome analysis of extracellular RNA (exRNA) purified from human biofluids is challenging because of the low RNA concentration and compromised RNA integrity. Here, we describe an optimized workflow to (1) isolate exRNA f
Externí odkaz:
https://doaj.org/article/7bfd217891a641cf956cdf736c0d0699
Autor:
Alexander Crits-Christoph, Rose S. Kantor, Matthew R. Olm, Oscar N. Whitney, Basem Al-Shayeb, Yue Clare Lou, Avi Flamholz, Lauren C. Kennedy, Hannah Greenwald, Adrian Hinkle, Jonathan Hetzel, Sara Spitzer, Jeffery Koble, Asako Tan, Fred Hyde, Gary Schroth, Scott Kuersten, Jillian F. Banfield, Kara L. Nelson
Publikováno v:
mBio, Vol 12, Iss 1 (2021)
Viral genome sequencing has guided our understanding of the spread and extent of genetic diversity of SARS-CoV-2 during the COVID-19 pandemic. SARS-CoV-2 viral genomes are usually sequenced from nasopharyngeal swabs of individual patients to track vi
Externí odkaz:
https://doaj.org/article/54dcf97842cf44cba3fb2df0de7c1099
Autor:
Justin Rendleman, Zhe Cheng, Shuvadeep Maity, Nicolai Kastelic, Mathias Munschauer, Kristina Allgoewer, Guoshou Teo, Yun Bin Matteo Zhang, Amy Lei, Brian Parker, Markus Landthaler, Lindsay Freeberg, Scott Kuersten, Hyungwon Choi, Christine Vogel
Publikováno v:
eLife, Vol 7 (2018)
Maintaining a healthy proteome involves all layers of gene expression regulation. By quantifying temporal changes of the transcriptome, translatome, proteome, and RNA-protein interactome in cervical cancer cells, we systematically characterize the mo
Externí odkaz:
https://doaj.org/article/e1259edd00ef41248b581f62bd38707f
Autor:
Jesse M Gray, David A Harmin, Sarah A Boswell, Nicole Cloonan, Thomas E Mullen, Joseph J Ling, Nimrod Miller, Scott Kuersten, Yong-Chao Ma, Steven A McCarroll, Sean M Grimmond, Michael Springer
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89673 (2014)
mRNA synthesis, processing, and destruction involve a complex series of molecular steps that are incompletely understood. Because the RNA intermediates in each of these steps have finite lifetimes, extensive mechanistic and dynamical information is e
Externí odkaz:
https://doaj.org/article/1a3d01b1100d44b6a39d16e65f33d481
Autor:
Saleh Tamim, Dat T Vo, Philip J Uren, Mei Qiao, Eckart Bindewald, Wojciech K Kasprzak, Bruce A Shapiro, Helder I Nakaya, Suzanne C Burns, Patricia R Araujo, Ichiro Nakano, Agnes J Radek, Scott Kuersten, Andrew D Smith, Luiz O F Penalva
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85591 (2014)
miR-137 plays critical roles in the nervous system and tumor development; an increase in its expression is required for neuronal differentiation while its reduction is implicated in gliomagenesis. To evaluate the potential of miR-137 in glioblastoma
Externí odkaz:
https://doaj.org/article/07dfca16fddd4fbc9d890bfd951dd082
Autor:
Brian B Tuch, Rebecca R Laborde, Xing Xu, Jian Gu, Christina B Chung, Cinna K Monighetti, Sarah J Stanley, Kerry D Olsen, Jan L Kasperbauer, Eric J Moore, Adam J Broomer, Ruoying Tan, Pius M Brzoska, Matthew W Muller, Asim S Siddiqui, Yan W Asmann, Yongming Sun, Scott Kuersten, Melissa A Barker, Francisco M De La Vega, David I Smith
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9317 (2010)
Due to growing throughput and shrinking cost, massively parallel sequencing is rapidly becoming an attractive alternative to microarrays for the genome-wide study of gene expression and copy number alterations in primary tumors. The sequencing of tra
Externí odkaz:
https://doaj.org/article/d57e33fd8331426db6efefa7bbcd91fb
Publikováno v:
Nature Biotechnology.
Autor:
Aravind Natarajan, Brayon J. Fremin, Danica T. Schmidtke, Marlene K. Wolfe, Soumaya Zlitni, Katherine E. Graham, Erin F. Brooks, Christopher J. Severyn, Kathleen M. Sakamoto, Norman J. Lacayo, Scott Kuersten, Jeff Koble, Glorianna Caves, Inna Kaplan, Upinder Singh, Prasanna Jagannathan, Andrew R. Rezvani, Ami S. Bhatt, Alexandria B. Boehm
Publikováno v:
bioRxiv
Microbial source tracking (MST) identifies sources of fecal contamination in the environment using fecal host-associated markers. While there are numerous bacterial MST markers, there are few viral markers. Here we design and test novel viral MST mar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff045919a78d04204938aa0d65d34557
https://europepmc.org/articles/PMC9882089/
https://europepmc.org/articles/PMC9882089/