Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Scott K. Adney"'
Autor:
Scott K. Adney, John J. Millichap, Jean‐Marc DeKeyser, Tatiana Abramova, Christopher H. Thompson, Alfred L. George Jr
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1488-1501 (2020)
Abstract Objective We identified a novel de novo SCN2A variant (M1879T) associated with infantile‐onset epilepsy that responded dramatically to sodium channel blocker antiepileptic drugs. We analyzed the functional and pharmacological consequences
Externí odkaz:
https://doaj.org/article/00621ebc305d48fe9c645cc9868c7015
Publikováno v:
Journal of Neurosurgery: Case Lessons. 4
BACKGROUND Focal cortical dysplasias (FCDs) are a heterogenous cluster of histopathologic entities classically associated with medically refractory epilepsy. Because there is substantial histopathologic variation among different types of FCD, there a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4c948e3f48abf208d60e0c5eb8207c
https://doi.org/10.3171/case22112
https://doi.org/10.3171/case22112
Autor:
Tatiana Abramova, Christopher H. Thompson, Alfred L. George, John Millichap, Jean Marc DeKeyser, Scott K. Adney
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1488-1501 (2020)
Annals of Clinical and Translational Neurology, Vol 7, Iss 9, Pp 1488-1501 (2020)
Objective We identified a novel de novo SCN2A variant (M1879T) associated with infantile‐onset epilepsy that responded dramatically to sodium channel blocker antiepileptic drugs. We analyzed the functional and pharmacological consequences of this v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ad789da9882034e04039851567e37fa
http://europepmc.org/articles/PMC7480906
http://europepmc.org/articles/PMC7480906
Autor:
Alfred L. George, Jean Marc DeKeyser, Scott K. Adney, Christopher H. Thompson, John Millichap, Tatiana Abramova
ObjectiveWe identified a novel de novo SCN2A variant (M1879T) associated with infantile-onset epilepsy that responded dramatically to sodium channel blocker antiepileptic drugs. We analyzed the functional and pharmacological consequences of this vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f01fd293f87700ebf064d41f2ecb66
Publikováno v:
Frontiers in Pharmacology, Vol 3 (2012)
Over the past 16 years, there has been an impressive number of ion channels shown to be sensitive to the major phosphoinositide in the plasma membrane, phosphatidilinositol 4,5-bisphosphate (PIP2). Among them are voltage-gated channels, which are cru
Externí odkaz:
https://doaj.org/article/2558a1756adf4254bd6019ee7f31f474
Autor:
Ricardo Costa, Peter Kopp, Mark Agulnik, Josh Waitzman, Lauren Chiec, Frank Giles, Young Kwang Chae, Maria Matsangou, Scott K. Adney, Benedito A. Carneiro
Publikováno v:
Oncotarget
As immunotherapies including tyrosine kinase inhibitors become more widely used for the treatment of a variety of malignancies, it is important for prescribers and patients to understand the potential adverse effects associated with these drugs. It i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38cbc6ef400185b1d16aadb7762a99c7
https://doi.org/10.18632/oncotarget.25606
https://doi.org/10.18632/oncotarget.25606
Autor:
Scott K. Adney, Mayra Delgado-Ramírez, Jorge Arreola, Aldo A. Rodríguez-Menchaca, Iván A. Aréchiga-Figueroa, Carlos A. Villalba-Galea, José J. De Jesús-Pérez, Diomedes E. Logothetis
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Phosphatidylinositol 4,5-bisphosphate (PIP2) is a membrane phospholipid that regulates the function of multiple ion channels, including some members of the voltage-gated potassium (Kv) channel superfamily. The PIP2 sensitivity of Kv channels is well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997056efc903ea1b0588c609bcfcd9d5
http://link.springer.com/article/10.1038/s41598-018-20280-w
http://link.springer.com/article/10.1038/s41598-018-20280-w
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 460:321-341
The plasma membrane phosphoinositide phosphatidylinositol 4,5-bisphosphate (PIP2) controls the activity of most ion channels tested thus far through direct electrostatic interactions. Mutations in channel proteins that change their apparent affinity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961a79b55dfb4a6644c4605b16681303
https://doi.org/10.1007/s00424-010-0828-y
https://doi.org/10.1007/s00424-010-0828-y
Inwardly rectifying potassium channels enforce tight control of resting membrane potential in excitable cells. The Kir3.2 channel, a member of the Kir3 subfamily of G-protein-activated potassium channels (GIRKs), plays several roles in the nervous sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae707bdd890a53a3ca79ab17f9c4c0c
https://europepmc.org/articles/PMC4683693/
https://europepmc.org/articles/PMC4683693/
Autor:
Diomedes E, Logothetis, Rahul, Mahajan, Scott K, Adney, Junghoon, Ha, Takeharu, Kawano, Xuan-Yu, Meng, Meng, Cui
Publikováno v:
International review of neurobiology. 123
The question that started with the pioneering work of Otto Loewi in the 1920s, to identify how stimulation of the vagus nerve decreased heart rate, is approaching its 100th year anniversary. In the meantime, we have learned that the neurotransmitter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25334e838601042c4c861fcca80196e6
https://pubmed.ncbi.nlm.nih.gov/26422981
https://pubmed.ncbi.nlm.nih.gov/26422981