Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Scott Jason Sawyer"'
Autor:
David Schaer, Chandrasekar V. Iyer, Ivan Inigo, Douglas W. Beight, Stephen Castaneda, Xiaohong Xu, Talbi Kaoudi, Sajan Joseph, Zhao Gaiying, Amy Pappas, Karen S. Britt, Karim A. Benhadji, David Surguladze, Saravanan Parthasarathy, Huaxing Pei, Scott Jason Sawyer, William T. McMillen, Bryan D. Anderson, Huimin Bian, Michael Kalos, Kyla Driscoll
Publikováno v:
Cancer Research. 77:955-955
The transforming growth factor β (TGFβ) signaling pathway is a pleiotropic cellular pathway that plays a critical role in cancer. In fact, aggressive tumors are typically associated with high ligand levels and thus associated with poor prognosis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da73ad2126f7259a3fc50c956783f9bb
https://doi.org/10.1158/1538-7445.am2017-955
https://doi.org/10.1158/1538-7445.am2017-955
Autor:
Robert D. Foreman, Lei Yan, Jeremy R. Graff, Scott Jason Sawyer, Jonathan M. Yingling, Stephen Parsons, Spring Weir, Michael Lahn
Publikováno v:
Molecular Cancer Therapeutics. 10:C201-C201
TGF-β signals through the type I and type II TGF-β receptors (TGFβRI and TGFβRII) to phosphorylate the SMAD proteins. In normal tissues, this signaling axis provides a growth inhibitory signal. However, in some cancers, TGF-β is often secreted a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f5962bcc287e6867ca9d3adb8d59fe4
https://doi.org/10.1158/1535-7163.targ-11-c201
https://doi.org/10.1158/1535-7163.targ-11-c201