Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Scott J. Westenberger"'
Autor:
Scott J Westenberger, Colleen M McClean, Rana Chattopadhyay, Neekesh V Dharia, Jane M Carlton, John W Barnwell, William E Collins, Stephen L Hoffman, Yingyao Zhou, Joseph M Vinetz, Elizabeth A Winzeler
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 4, p e653 (2010)
Up to 40% of the world's population is at risk for Plasmodium vivax malaria, a disease that imposes a major public health and economic burden on endemic countries. Because P. vivax produces latent liver forms, eradication of P. vivax malaria is more
Externí odkaz:
https://doaj.org/article/c288af25ddc3439ca1ea59076ca98769
Autor:
Paul B. Samollow, Susan M. Mahaney, Nicolas Gouin, Scott J. Westenberger, Peter Lindley, John L. VandeBerg
Publikováno v:
Genome. 48:1019-1027
Short-tandem-repeat (SSR) or microsatellite polymorphisms are some of the most extensively employed genetic markers in contemporary linkage mapping studies. To date, only a limited number of microsatellites have been isolated in the gray, short-taile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8b08d8ee3a378d7830f5b639694929
https://doi.org/10.1139/g05-059
https://doi.org/10.1139/g05-059
Publikováno v:
Genetics. 171:527-543
Genetic variation in Trypanosoma cruzi is likely a key determinant in transmission and pathogenesis of Chagas disease. We have examined nine loci as markers for the extant T. cruzi strains. Four distinct alleles were found for each locus, correspondi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21833389e846d97c69f80be9022b156
https://doi.org/10.1534/genetics.104.038745
https://doi.org/10.1534/genetics.104.038745
Publikováno v:
Gene. 352:100-108
The spliced leader RNA gene (SL RNA) repeat is present in large multicopy arrays and has been used as a marker for the diversity of kinetoplastid protozoans. Intra-array variation could affect conclusions made using a randomly isolated repeat as a ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb0e18780cf5d54384281f8bec38021
https://doi.org/10.1016/j.gene.2005.04.002
https://doi.org/10.1016/j.gene.2005.04.002
Publikováno v:
Current Molecular Medicine. 4:549-562
As a consequence of infection by Trypanosoma cruzi, 30% of victims may develop chronic Chagas disease, which presents a spectrum of pathology including cardiomyopathy, megacolon and megaesophagus. The outcome of infection in a particular individual i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2e6f676f9ae02278e2aff34e82176b
https://doi.org/10.2174/1566524043360249
https://doi.org/10.2174/1566524043360249
Autor:
Sergei A. Podlipaev, Michel Dollet, Julius Lukeš, Octavio Fernandes, Nancy R. Sturm, David A. Campbell, Ivan Fiala, Scott J. Westenberger
Publikováno v:
The Journal of Eukaryotic Microbiology. 51:283-290
We have determined the sequences of 5S rRNA and spliced leader (SL) RNA genes, and adjacent intergenic regions for representatives of all known trypanosomatid genera parasitizing insects. The genetic loci have been analyzed separately as well as by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46675076391324e256d7d26e997384e1
https://doi.org/10.1111/j.1550-7408.2004.tb00568.x
https://doi.org/10.1111/j.1550-7408.2004.tb00568.x
Publikováno v:
International Journal for Parasitology. 33:269-279
A role for parasite genetic variability in the spectrum of Chagas disease is emerging but not yet evident, in part due to an incomplete understanding of the population structure of Trypanosoma cruzi. To investigate further the observed genotypic vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a5adf34915def8582ecc586aae88f7
https://doi.org/10.1016/s0020-7519(02)00264-3
https://doi.org/10.1016/s0020-7519(02)00264-3
Publikováno v:
Molecular Ecology Notes. 5:87-89
Twenty-six polymorphic microsatellite markers were isolated from (AC) n and (AG) n microsatellite-enhanced genomic libraries of the gray, short-tailed opossum Monodelphis domestica . All 26 loci showed high allelic diversity, with allele numbers rang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d94f6791e872381da96fad4607b13c54
https://doi.org/10.1111/j.1471-8286.2004.00841.x
https://doi.org/10.1111/j.1471-8286.2004.00841.x
Autor:
Neekesh V. Dharia, John R. Walker, Glenn C. Federe, Rachel Borboa, John W. Barnwell, Kelli Kuhen, Serge Batalov, Alejandro Llanos-Cuentas, Colleen M. McClean, Joseph M. Vinetz, S. Whitney Barnes, A. Taylor Bright, Elizabeth A. Winzeler, Scott J. Westenberger, Victor Neyra
Plasmodium vivax causes 25–40% of malaria cases worldwide, yet research on this human malaria parasite has been neglected. Nevertheless, the recent publication of the P. vivax reference genome now allows genomics and systems biology approaches to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753b1b0326ec85c1a945190051e2c1d9
https://europepmc.org/articles/PMC2993397/
https://europepmc.org/articles/PMC2993397/
Autor:
Scott J. Westenberger, Jeffrey D. Dvorin, Thomas J. Wandless, Derek C. Martyn, David A. Baker, Christine S. Hopp, A. Taylor Bright, Christine R. Collins, Joshua S. Grimley, Manoj T. Duraisingh, Michael J. Blackman, Elizabeth A. Winzeler, Saurabh D. Patel
Publikováno v:
Science; Vol 328
It's a Knockout The malaria parasite is one of the most important pathogens of humans. Increasing drug-resistance is an imminent public health disaster, and we urgently need to find new drugs. The recently acquired malarial genomes provide a plethora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38667dda239883c8457379792b348e68
https://pubmed.ncbi.nlm.nih.gov/21394953
https://pubmed.ncbi.nlm.nih.gov/21394953