Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Scott J. Pearson"'
Autor:
Steven W. Wall, Lilia Sanchez, Kelly Scribner Tuttle, Scott J. Pearson, Shivatheja Soma, Garhett L. Wyatt, Hannah N. Carter, Ramsey M. Jenschke, Lin Tan, Sara A. Martinez, Philip L. Lorenzi, Vishal M. Gohil, Monique Rijnkels, Weston W. Porter
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 5, Pp 1046-1063 (2023)
Abstract Dysregulation of cellular metabolism is a hallmark of breast cancer progression and is associated with metastasis and therapeutic resistance. Here, we show that the breast tumor suppressor gene SIM2 promotes mitochondrial oxidative phosphory
Externí odkaz:
https://doaj.org/article/053db100e0644f5393e7cef5cb54595e
Autor:
Scott J. Pearson, Jessica Elswood, Rola Barhoumi, Brittini Ming-Whitfield, Monique Rijnkels, Weston W. Porter
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Background Mutations in genes associated with homologous recombination (HR) increase an individual’s risk of developing triple-negative breast cancer (TNBC). Although known for their role in repairing dsDNA breaks, HR repair elements also
Externí odkaz:
https://doaj.org/article/1fd0c61af2304bf5b0389420b309c047
Autor:
Lilia Sanchez, Jessica Epps, Steven Wall, Cole McQueen, Scott J. Pearson, Kelly Scribner, Elizabeth A. Wellberg, Erin D. Giles, Monique Rijnkels, Weston W. Porter
Publikováno v:
Cell Death & Differentiation.
The functionally differentiated mammary gland adapts to extreme levels of stress from increased demand for energy by activating specific protective mechanisms to support neonatal health. Here, we identify the breast tumor suppressor gene, single-mind
Autor:
Monique Rijnkels, Weston Porter, Scott J. Pearson, Jessica Elswood, Rola Barhoumi, H. Ross Payne
Publikováno v:
Autophagy
Mitochondria operate as a central hub for many metabolic processes by sensing and responding to the cellular environment. Developmental cues from the environment have been implicated in selective autophagy, or mitophagy, of mitochondria during cell d
Autor:
Monique Rijnkels, Scott J. Pearson, Jessica Elswood, Weston Porter, Rola Barhoumi, Brittini Ming-Whitfield
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-14 (2019)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background Mutations in genes associated with homologous recombination (HR) increase an individual’s risk of developing triple-negative breast cancer (TNBC). Although known for their role in repairing dsDNA breaks, HR repair elements also stabilize
Autor:
Rola Barhoumi, Emily E. Schmitt, Kelly C. Scribner, Scott J. Pearson, Jessica Elswood, Garhett L. Wyatt, Fariba Behbod, Weston Porter, Steven W. Wall, Tapasree Roy Sarkar, Cole M. McQueen, Monique Rijnkels
Publikováno v:
Oncogene
There is increasing evidence that genomic instability is a prerequisite for cancer progression. Here we show that SIM2s, a member of the bHLH/PAS family of transcription factors, regulates DNA damage repair through enhancement of homologous recombina
This work was supported by the Engineering and Physical Sciences Research Council (grants EP/L017008/1, EP/G03673X/1 and EP/J009016/1) and the European Research Council (grant 321305). I. D. W. S. acknowledges a Royal Society Wolfson Research Merit A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02065ad0145618c443219b698e95b467
https://hdl.handle.net/10023/17163
https://hdl.handle.net/10023/17163
Autor:
Andrew B. Matheson, Dimali A. Vithanage, Vidmantas Gulbinas, Vytenis Pranculis, Gordon J. Hedley, Scott J. Pearson, Ifor D. W. Samuel, Arvydas Ruseckas
The work in St Andrews was supported by the Engineering and Physical Sciences Research Council (grants EP/L017008/1, EP/J009016/1 and EP/G03673X/1) and the European Research Council (grant 321305). The work in Vilnius was supported by the Research Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c16306f24719e07aa91fb45bf97772f
https://hdl.handle.net/10023/13676
https://hdl.handle.net/10023/13676
Autor:
Thomas B. Parnell, Ben T. Vinson, Gary W. Boehm, Dinko Kranjac, Michael J. Chumley, Marielle K. Weintraub, Scott J. Pearson, Jigna Patel, Micah J. Eimerbrink, Whitney M. Summers
Publikováno v:
Behavioural Brain Research. 266:183-187
Alzheimer's disease (AD) is a progressive disorder characterized by neuronal and behavioral deterioration. Two hallmark pathologies of AD are amyloid-beta (Aβ) plaques and neurofibrillary tangles, and the presence of such pathology can limit cell-to
Publikováno v:
The Journal of Physical Chemistry Letters. 4:4166-4171
The mechanism by which Coulombically bound charge pairs dissociate into free carriers in photovoltaic donor–acceptor blends is of great interest. Here, we use polarization-sensitive transient absorption (TA) to study the diffusion of photogenerated