Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Scott J. Patterson"'
Publikováno v:
Frontiers in Immunology, Vol 3 (2012)
The relative activity of regulatory versus conventional CD4+ T cells ultimately maintains the delicate balance between immune tolerance and inflammation. At the molecular level, the activity of phosphatidylinositol 3-kinase (PI3K) and its downstream
Externí odkaz:
https://doaj.org/article/276fe35e968e4d63b87c1d374fe65d25
Publikováno v:
BMJ Case Reports. 14:e243526
A 93-year-old man was admitted with 1 week of frank jaundice and abdominal pain. His medical history included diffuse large B-cell lymphoma treated with rituximab and cyclophosphamide, hydroxydaunomycin, oncovin and prednisolone (R-CHOP) chemotherapy
Autor:
Constadina Panagiotopoulos, Timothy J. Kieffer, Adele Y. Wang, Rusung Tan, Megan K. Levings, Anne M. Pesenacker, Jana Gillies, C. Bruce Verchere, Scott J. Patterson, Majid Mojibian, Kim Morishita
Publikováno v:
Journal of Clinical Investigation. 126:1039-1051
T regulatory cells (Tregs) control immune homeostasis by preventing inappropriate responses to self and nonharmful foreign antigens. Tregs use multiple mechanisms to control immune responses, all of which require these cells to be near their targets
Autor:
James G. Schmitt, John W. Fisher, Michael P. Neeley, David F. Pac, Frankie D. Jackson, Scott J. Patterson, Jennifer L. Aschoff, Stuart R. Challender
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ddf29d75d4f267de520897fb294ef7e
https://doi.org/10.1130/2017.2528
https://doi.org/10.1130/2017.2528
Publikováno v:
The Journal of Immunology. 192:623-629
Chronic inflammation is known to promote metabolic dysregulation in obesity and type 2 diabetes. Although the precise origin of the unchecked inflammatory response in obesity is unclear, it is known that overproduction of proinflammatory cytokines by
Publikováno v:
Liver Transplantation. 19:268-274
Without effective prophylaxis, liver transplantation for hepatitis B virus (HBV)–related liver disease is frequently complicated by severe and rapidly progressive HBV recurrence. Combination prophylaxis with hepatitis B immune globulin (HBIG) and l
Autor:
Marianna Politou, Antonio Almeida, Vincenzo Cerundolo, Amin Rahemtulla, Anastasios Karadimitris, Richard R. Schmidt, Ioannis Kotsianidis, Bini Matthew, Scott J. Patterson, Irene Roberts
Publikováno v:
CIÊNCIAVITAE
Scopus-Elsevier
Scopus-Elsevier
NKT cells are a small subset of regulatory T cells conserved in humans and mice. In humans they express the Vα24Jα18 invariant chain (hence invariant NKT (iNKT) cells) and are restricted by the glycolipid-presenting molecule CD1d. In mice, iNKT cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de81fae6a88db7b08e407e8826f852b3
https://doi.org/10.4049/jimmunol.175.8.5087
https://doi.org/10.4049/jimmunol.175.8.5087
Autor:
Irene Roberts, Alessandro Poggi, Anastasios Karadimitris, Aristeidis Chaidos, David C. A. Neville, Terry D. Butters, Scott J. Patterson
Invariant NKT (iNKT) cells are a subset of highly conserved immunoregulatory T cells that modify a variety of immune responses, including alloreactivity. Central to their function is the interaction of the invariant TCR with glycosphingolipid (GSL) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6d181ea2d4fee0a399328ed42b544b
https://doi.org/10.4049/jimmunol.181.5.3268
https://doi.org/10.4049/jimmunol.181.5.3268
Autor:
Stuart K. Roberts, Scott Bowden, Simone I. Strasser, Paul V. Desmond, Kaye Marion, Stephen Locarnini, Scott J. Patterson, William Sievert, Amanda Nicoll, Alice Lee, Alexander J. Thompson, Lucy Lim, Peter W Angus, Jacob George
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver. 37(6)
Background: Multidrug-resistant HBV continues to be an important clinical problem. The TDF-109 study demonstrated that TDF±LAM is an effective salvage therapy through 96 weeks for LAM-resistant patients who previously failed ADV add-on or switch the
Autor:
Edward Kanfer, Donald McDonald, Aristeidis Chaidos, Scott J. Patterson, Anastasios Karadimitris, John M. Goldman, John C. Davis, Katy Rezvani, Irene Roberts, David Marin, Jane F. Apperley, Amin Rahemtulla, Jiri Pavlu, Mohammed Suhail Chaudhry, Richard Szydlo, Francesco Dazzi, Dragana Milojkovic
Publikováno v:
Blood. 119:5030-5036
Invariant natural killer T (iNKT) cells are powerful immunomodulatory cells that in mice regulate a variety of immune responses, including acute GVHD (aGVHD). However, their clinical relevance and in particular their role in clinical aGVHD are not kn