Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Scott J. Callahan"'
Autor:
Scott J. Callahan, Stephanie Tepan, Yan M. Zhang, Helen Lindsay, Alexa Burger, Nathaniel R. Campbell, Isabella S. Kim, Travis J. Hollmann, Lorenz Studer, Christian Mosimann, Richard M. White
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
Transgenic animals are invaluable for modeling cancer genomics, but often require complex crosses of multiple germline alleles to obtain the desired combinations. Zebrafish models have advantages in that transgenes can be rapidly tested by mosaic exp
Externí odkaz:
https://doaj.org/article/c69e5d887a054aa081192f7f3df7e11f
Autor:
Scott J Callahan, Yvette A Luyten, Yogesh K Gupta, Geoffrey G Wilson, Richard J Roberts, Richard D Morgan, Aneel K Aggarwal
Publikováno v:
PLoS Biology, Vol 14, Iss 4, p e1002442 (2016)
The creation of restriction enzymes with programmable DNA-binding and -cleavage specificities has long been a goal of modern biology. The recently discovered Type IIL MmeI family of restriction-and-modification (RM) enzymes that possess a shared targ
Externí odkaz:
https://doaj.org/article/35e0325c03de4884acbf1c4e9414666d
Autor:
Emily Montal, Sarah C. Perlee, Theresa Simon-Vermot, Scott J. Callahan, Barry S. Taylor, Tuan Trieu, Ekta Khurana, Richard M. White, Yujie Fan, Sam E. Tischfield, Ting-Hsiang Huang, Yilun Ma, Shruthy Suresh, Lorenz Studer, Satish K. Tickoo, Richard Koche, Arianna Baggiolini, Nathalie Saurat, Miranda V. Hunter, Joshua M. Weiss, Ryan M. Walsh, Nathaniel R. Campbell, Mohita Tagore, Travis J. Hollmann
Publikováno v:
Science. 373
Chromatin state and oncogenic competence Although specific DNA mutations can lead to tumor generation, they are not transforming in all cellular contexts. This may be due to the intrinsic transcriptional program present in the cell of origin. Using z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78b19cc9b63340f3d9157007405afa4b
https://doi.org/10.1126/science.abc1048
https://doi.org/10.1126/science.abc1048
Autor:
Richard M. White, Theresa Simon-Vermot, Tuan Trieu, Travis J. Hollmann, Emily Montal, Scott J. Callahan, Lorenz Studer, Barry S. Taylor, Satish K. Tickoo, Arianna Baggiolini, Richard Koche, Mohita Tagore, Nathalie Saurat, Ekta Khurana, Yujie Fan, Sam E. Tischfield, Joshua M. Weiss, Nathaniel R. Campbell
Oncogenes are only transforming in certain cellular contexts, a phenomenon called oncogenic competence. The mechanisms regulating this competence remain poorly understood. Here, using a combination of a novel human pluripotent stem cell (hPSC)-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e572918d7610d11233eaf62f54c50d
https://doi.org/10.1101/2020.05.09.081554
https://doi.org/10.1101/2020.05.09.081554
Autor:
Chelsea Rittenhouse, Scott J. Callahan, Sun Young Chung, Ting Zhou, Mark J. Tomishima, Sean D. Ryan, Lorenz Studer, Chao Zhang, Jason Tchieu, Nadja Zeltner, Doron Betel, Richard M. White, Kiran Ramnarine, Gustav Y. Cederquist, Shuibing Chen
Publikováno v:
Cell Stem Cell
Autism is a clinically heterogeneous neurodevelopmental disorder characterized by impaired social interactions, restricted interests, and repetitive behaviors. Despite significant advances in the genetics of autism, understanding how genetic changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fc92ae98bfa3ae4de47667f105d676
https://doi.org/10.1016/j.stem.2020.06.004
https://doi.org/10.1016/j.stem.2020.06.004
Autor:
Alexa Burger, Isabella S. Kim, Zhang Y, Christian Mosimann, Lorenz Studer, Travis J. Hollmann, Nathaniel R. Campbell, Helen Lindsay, Richard M. White, Stephanie Tepan, Scott J. Callahan
Publikováno v:
Disease Models & Mechanisms
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
Transgenic animals are invaluable for modeling cancer genomics, but often require complex crosses of multiple germline alleles to obtain the desired combinations. Zebrafish models have advantages in that transgenes can be rapidly tested by mosaic exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8867764ffafdb31e8740ff9c1a828c7d
https://doi.org/10.1242/dmm.034561
https://doi.org/10.1242/dmm.034561
Autor:
Talia Guardia, Milena A. Zimmer, Richard M. White, Myles Fennell, Jose Javier Bravo-Cordero, Julie Di Martino, Chandrani Mondal, Scott J. Callahan, Zhang Y, Toshimitsu Takagi, Ralph Garippa, Nathaniel R. Campbell
Publikováno v:
Developmental cell. 45(5)
Patterning of vertebrate melanophores is essential for mate selection and protection from UV-induced damage. Patterning can be influenced by circulating long-range factors, such as hormones, but it is unclear how their activity is controlled in recip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3f1cc996eef5943a6d62dd337c628b
https://pubmed.ncbi.nlm.nih.gov/29870715
https://pubmed.ncbi.nlm.nih.gov/29870715
Publikováno v:
Journal of Visualized Experiments.
Human pluripotent stem cells (hPSCs) represent a platform to study human development in vitro under both normal and disease conditions. Researchers can direct the differentiation of hPSCs into the cell type of interest by manipulating the culture con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aad846c94f877f6ad4f0df305c749c9
https://doi.org/10.3791/53806-v
https://doi.org/10.3791/53806-v
Autor:
Robert K. Prud'homme, Douglas H. Adamson, Susan Shao, Xuhong Guo, Rajesh K. Saini, Devang Amin, Jack Tinsley, Scott J. Callahan, Robert M. Kriegel
Publikováno v:
Energy & Fuels. 21:1301-1308
An in-depth understanding of the effects of polymer additives upon the rate, composition, and structure of paraffin deposition is required in the development of deep, off-shore oil fields to predict treatment strategies. To this end, we have develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c24a1f709e539dd92c69e46845ebcf8d
https://doi.org/10.1021/ef060446m
https://doi.org/10.1021/ef060446m
Autor:
Geoffrey G. Wilson, Richard D. Morgan, Rinku Jain, Richard J. Roberts, Aneel K. Aggarwal, Scott J. Callahan, Sharon A. Townson
Publikováno v:
Acta crystallographica. Section F, Structural biology and crystallization communications. 67(Pt 10)
Type IIL restriction enzymes have rejuvenated the search for user-specified DNA binding and cutting. By aligning and contrasting the highly comparable amino-acid sequences yet diverse recognition specificities across the family of enzymes, amino acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c7a4708b4b85f01946d6695bad0437e
https://pubmed.ncbi.nlm.nih.gov/22102043
https://pubmed.ncbi.nlm.nih.gov/22102043