Zobrazeno 1 - 10
of 261
pro vyhledávání: '"Scott J, Russo"'
Autor:
Eduardo R. Butelman, Yuefeng Huang, Flurin Cathomas, Pierre-Olivier Gaudreault, Panos Roussos, Scott J. Russo, Rita Z. Goldstein, Nelly Alia-Klein
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Opioid use disorders cause major morbidity and mortality, and there is a pressing need for novel mechanistic targets and biomarkers for diagnosis and prognosis. Exposure to mu-opioid receptor (MOR) agonists causes changes in cytokine and inf
Externí odkaz:
https://doaj.org/article/23fb906b517640f280f7a1f4c2cfdc2e
Autor:
Amni Al-Kachak, Giuseppina Di Salvo, Sasha L. Fulton, Jennifer C Chan, Lorna A. Farrelly, Ashley E. Lepack, Ryan M. Bastle, Lingchun Kong, Flurin Cathomas, Emily L. Newman, Caroline Menard, Aarthi Ramakrishnan, Polina Safovich, Yang Lyu, Herbert E. Covington, Li Shen, Kelly Gleason, Carol A. Tamminga, Scott J. Russo, Ian Maze
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Mood disorders are an enigmatic class of debilitating illnesses that affect millions of individuals worldwide. While chronic stress clearly increases incidence levels of mood disorders, including major depressive disorder (MDD), stress-media
Externí odkaz:
https://doaj.org/article/b2c5b24c092e46f3a1215efcaf06b44a
Autor:
Aki Takahashi, Romain Durand-de Cuttoli, Meghan E. Flanigan, Emi Hasegawa, Tomomi Tsunematsu, Hossein Aleyasin, Yoan Cherasse, Ken Miya, Takuya Okada, Kazuko Keino-Masu, Koshiro Mitsui, Long Li, Vishwendra Patel, Robert D. Blitzer, Michael Lazarus, Kenji F. Tanaka, Akihiro Yamanaka, Takeshi Sakurai, Sonoko Ogawa, Scott J. Russo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The dorsal raphe nucleus (DRN) is known to modulate aggressive behaviour in rodents. Here the authors show that glutamatergic projections from the lateral habenula to DRN modulate aggression between male mice.
Externí odkaz:
https://doaj.org/article/d04c343a8d9249c48d96d5f41f361fc1
Autor:
Carole Morel, Sarah E. Montgomery, Long Li, Romain Durand-de Cuttoli, Emily M. Teichman, Barbara Juarez, Nikos Tzavaras, Stacy M. Ku, Meghan E. Flanigan, Min Cai, Jessica J. Walsh, Scott J. Russo, Eric J. Nestler, Erin S. Calipari, Allyson K. Friedman, Ming-Hu Han
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Anxiety and depression are highly comorbid, yet the distinct or shared neurobiological correlates of anxiety remain elusive. Here, Morel et al. define that the midbrain projection to the basolateral amygdala control anxiety but not depression.
Externí odkaz:
https://doaj.org/article/d94aa0f05915423889c5257d381347f6
Autor:
Flurin Cathomas, Laura Bevilacqua, Aarthi Ramakrishnan, Hope Kronman, Sara Costi, Molly Schneider, Kenny L. Chan, Long Li, Eric J. Nestler, Li Shen, Dennis S. Charney, Scott J. Russo, James W. Murrough
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Ketamine has rapid and sustained antidepressant effects in patients with treatment-resistant depression (TRD). However, the underlying mechanisms of action are not well understood. There is increasing evidence that TRD is associated with a p
Externí odkaz:
https://doaj.org/article/9578aab04ada4803bcc382d8a0f3d527
Autor:
Luz H. Ospina, Katie Beck-Felts, Chloe Ifrah, Amanda Lister, Sylvie Messer, Scott J. Russo, James J. Gross, David Kimhy
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100536- (2022)
Emotion regulation (ER) strategies are thought to contribute to mental as well as physical health outcomes. Two common ER strategies include expressive suppression, or inhibition of emotional expression, and cognitive reappraisal, which involves chan
Externí odkaz:
https://doaj.org/article/a0ae774cab1d48db9cae6ec4293f0c3e
Autor:
Sara Costi, Laurel S. Morris, Abigail Collins, Nicolas F. Fernandez, Manishkumar Patel, Hui Xie, Seunghee Kim-Schulze, Emily R. Stern, Katherine A. Collins, Flurin Cathomas, Michael K. Parides, Alexis E. Whitton, Diego A. Pizzagalli, Scott J. Russo, James W. Murrough
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Increased levels of peripheral cytokines have been previously associated with depression in preclinical and clinical research. Although the precise nature of peripheral immune dysfunction in depression remains unclear, evidence from animal s
Externí odkaz:
https://doaj.org/article/ba742c5afe7d476aa19d67c3d88c7bb5
Autor:
Shannon L. Cole, Ramesh Chandra, Maya Harris, Ishan Patel, Torrance Wang, Hyunjae Kim, Leah Jensen, Scott J. Russo, Gustavo Turecki, Amy M. Gancarz-Kausch, David M. Dietz, Mary Kay Lobo
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-14 (2021)
Abstract Mitochondrial function is required for brain energy homeostasis and neuroadaptation. Recent studies demonstrate that cocaine affects mitochondrial dynamics and morphological characteristics within the nucleus accumbens (NAc). Further, mitoch
Externí odkaz:
https://doaj.org/article/9d6dd2987a8d4db7bdc5e26bc0388cab
Autor:
Lucy K. Bicks, Kazuhiko Yamamuro, Meghan E. Flanigan, Julia Minjung Kim, Daisuke Kato, Elizabeth K. Lucas, Hiroyuki Koike, Michelle S. Peng, Daniel M. Brady, Sandhya Chandrasekaran, Kevin J. Norman, Milo R. Smith, Roger L. Clem, Scott J. Russo, Schahram Akbarian, Hirofumi Morishita
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Isolation during critical periods of development prevents development of normal social behaviours in mice, and this is thought to involve the prefrontal cortex. Here, the authors identify an activation pattern in parvalbumin-positive interneurons in
Externí odkaz:
https://doaj.org/article/e3415caf868e48819828d52e7b559a2f
Autor:
Katherine B LeClair, Kenny L Chan, Manuella P Kaster, Lyonna F Parise, Charles Joseph Burnett, Scott J Russo
Publikováno v:
eLife, Vol 10 (2021)
Social hierarchy formation is strongly evolutionarily conserved. Across species, rank within social hierarchy has large effects on health and behavior. To investigate the relationship between social rank and stress susceptibility, we exposed ranked m
Externí odkaz:
https://doaj.org/article/62df174cf8144e55a4bf140d1dce987a