Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Scott H. Schelling"'
Autor:
Robert Austin-LaFrance, Lindsay Tomlinson, Lori A. Reed, Carrie A. Northcott, Wenhu Huang, Bradley E. Enerson, Daniel Morton, Scott H. Schelling, John M. Marcek
Publikováno v:
Toxicologic Pathology. 43:498-512
The toxicity of hydroxyurea, a treatment for specific neoplasms, sickle-cell disease, polycythemia, and thrombocytosis that kills cells in mitosis, was assessed in repeat-dose, oral gavage studies in rats and dogs and a cardiovascular study in teleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c7092afcdaf668395bdc073d8a0f65
https://doi.org/10.1177/0192623314559103
https://doi.org/10.1177/0192623314559103
Autor:
Lynette A. Fouser, Scott H. Schelling, Andre-Jean Lambert, Kyriaki Dunussi-Joannopoulos, Quintus G. Medley, Hak-Ling Ma, Cheryl Nickerson-Nutter, Debra G. Goodwin, Kathleen Shields, Debra D. Pittman, Yijun Carrier, Mary Collins, Spencer Liang
Publikováno v:
The Journal of Immunology. 185:5531-5538
IL-22 is made by a unique set of innate and adaptive immune cells, including the recently identified noncytolytic NK, lymphoid tissue-inducer, Th17, and Th22 cells. The direct effects of IL-22 are restricted to nonhematopoietic cells, its receptor ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2455eb8047b810dd20814ab7b68bb83
https://doi.org/10.4049/jimmunol.0904091
https://doi.org/10.4049/jimmunol.0904091
Autor:
Debra G. Goodwin, Tarek S. Mansour, Kenneth C. Appell, Katherine J. Seidl, Amha G. Hewet, Maria L. Webb, Min Gao, James D. Clark, Steve Tam, Martin Hegen, Elizabeth Quadros, Peter T. Symanowicz, Jenny Togias, Jennifer Lussier, Scott H. Schelling, Michael Ohlmeyer, Bojing Wang, Xin Xu, Earl F. Kimble, Mary Collins, Jorge Quintero, Rustem Krykbaev, Dejun Xuan, Cheryl Nickerson-Nutter, Richard Harrison, Yuefei Shao, Christopher Wrocklage, Tsung H. Lin, Andrew G. Cole
Publikováno v:
Arthritis & Rheumatism. 62:2283-2293
Objective All γ-chain cytokines signal through JAK-3 and JAK-1 acting in tandem. We undertook this study to determine whether the JAK-3 selective inhibitor WYE-151650 would be sufficient to disrupt cytokine signaling and to ameliorate autoimmune dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef4a0c33e1ad1789a4ae6c55e946b7c
https://doi.org/10.1002/art.27536
https://doi.org/10.1002/art.27536
Autor:
Tracey Blanchet, Manas K. Majumdar, Nancy Stedman, Elisabeth A. Morris, Bei Hopkins, S.S. Glasson, Scott H. Schelling, Roger Askew
Publikováno v:
Arthritis & Rheumatism. 56:3670-3674
Objective To phenotypically characterize ADAMTS-4– and ADAMTS-5–double-knockout mice, and to determine the effect of deletion of ADAMTS-4 and ADAMTS-5 on the progression of osteoarthritis (OA) in mice. Methods Mice lacking the catalytic domain of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38dc6d56c8c7be8bdfa01192a26c645f
https://doi.org/10.1002/art.23027
https://doi.org/10.1002/art.23027
Autor:
Samuel J. Goldman, Aiping Jiao, Scott H. Schelling, Cara Williams, Susan Fish, Lawrence Mason
Publikováno v:
Annals of Allergy, Asthma & Immunology. 98:83-88
Background Several studies indicate that selectin-mediated leukocyte migration may depend on the types of initiating inflammatory stimuli or on the vascular beds involved in the inflammatory response. Thus, targeting selectin interactions to treat in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4ee9b378d1a175c8bc89724f18da0b
https://doi.org/10.1016/s1081-1206(10)60864-2
https://doi.org/10.1016/s1081-1206(10)60864-2
Autor:
Edward J. Kilbourne, Gregory Weber, Scott H. Schelling, Raghuram S. Tangirala, Carl Morris, Dennis Powell, Adam M. Gilbert, Thomas Kenney, Sunil Nagpal, Michael St. Andre, Jane Owens, Mark Johnson, Sue Chiparri, Patrick Robert Verhoest, Rayomond Unwalla, Chris McNally, T. A. Khan, Eugene Lvovich Piatnitski Chekler, Catherine Thompson, James T. Anderson
Publikováno v:
Journal of medicinal chemistry. 57(6)
We present a novel series of selective androgen receptor modulators (SARMs) which shows excellent biological activity and physical properties. 1-(2-Hydroxy-2-methyl-3-phenoxypropanoyl)-indoline-4-carbonitriles showed potent binding to the androgen re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9df0694a05aa1f82ea6bcdfcce1faa8
https://pubmed.ncbi.nlm.nih.gov/24527807
https://pubmed.ncbi.nlm.nih.gov/24527807
Publikováno v:
Journal of Veterinary Internal Medicine. 6:235-244
Seventeen dogs were diagnosed with leptospirosis on the basis of clinical findings, laboratory abnormalities, and serology. This article summarizes and characterizes the historical and physical findings, laboratory data, serology, treatment, and outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c8a00d34ead5d975b6b771b5be5e77
https://doi.org/10.1111/j.1939-1676.1992.tb00345.x
https://doi.org/10.1111/j.1939-1676.1992.tb00345.x
Publikováno v:
Journal of Medical Primatology. 20:82-88
A juvenile rhesus macaque (Macaca mulatta) developed a symmetrical erosive polyarthritis involving both large and small diarthrodial joints. Neither an infectious nor a metabolic etiology could be determined. This case shares many clinical and pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6173773674327865977c2425765b3065
https://doi.org/10.1111/j.1600-0684.1991.tb00496.x
https://doi.org/10.1111/j.1600-0684.1991.tb00496.x
Publikováno v:
Veterinary Radiology. 31:268-272
Hepatic nodular hyperplasia is a benign, usually clinically inapparent, proliferative lesion commonly found at necropsy in older dogs. Three examples of hepatic nodular hyperplasia are described in dogs with clinical signs compatible with hepatic dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bab4cadfbb68cea0f5466af3766e3ea
https://doi.org/10.1111/j.1740-8261.1990.tb00800.x
https://doi.org/10.1111/j.1740-8261.1990.tb00800.x
Publikováno v:
Veterinary Radiology. 31:203-206
A urinoma is an encapsulated extravasation of urine. In this case history report, the radiographic and ultrasonographic features of a urinoma in a dog are described. The dog presented with a palpable mass in the right flank which developed following
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::943ed084c63de695476d69eec1f4bf6b
https://doi.org/10.1111/j.1740-8261.1990.tb01812.x
https://doi.org/10.1111/j.1740-8261.1990.tb01812.x