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pro vyhledávání: '"Scott H. Buck"'
Autor:
Scott H. Buck, Richard L. Moss
Publikováno v:
Comprehensive Physiology
The sections in this article are: 1 Contractile and Regulatory Proteins of the Cardiac Myofibril 1.1 Myosin 1.2 Actin 1.3 Troponin 1.4 Tropomyosin 1.5 C-Protein 2 Mechanical Properties of Myocardium 2.1 Isometric Tension 2.2 Shortening Velocity 2.3 T
Autor:
Mariappan Muthuchamy, Jitandrakumar R. Patel, Richard L. Moss, David F. Wieczorek, Daniel P. Fitzsimons, Scott H. Buck
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 280:H2732-H2739
In myocardium, protein kinase A (PKA) is known to phosphorylate troponin I (TnI) and myosin-binding protein-C (MyBP-C). Here, we used skinned myocardial preparations from nontransgenic (NTG) mouse hearts expressing 100% α-tropomyosin (α-Tm) to exam
Autor:
R. John Solaro, Scott H. Buck, Hua Lin, Beata M. Wolska, Miroslav O. Stojanovic, Richard C. Fentzke, Jeffrey M. Leiden, Jitandrakumar R. Patel, Richard L. Moss, Anne F. Martin
Publikováno v:
The Journal of Physiology. 517:143-157
1. To assess the specific functions of the cardiac isoform of troponin I (cTnI), we produced transgenic mice that expressed slow skeletal troponin I (ssTnI) specifically in cardiomyocytes. Cardiomyocytes from these mice displayed quantitative replace
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 276:H1167-H1171
To investigate the role of myosin regulatory light chain isoforms as a determinant of the kinetics of cardiac contraction, unloaded shortening velocity was determined by the slack-test method in skinned wild-type murine atrial cells and transgenic ce
Autor:
Timothy E. Hewett, Raisa Klevitsky, Scott H. Buck, Jeffrey Robbins, Richard L. Moss, James Gulick
Publikováno v:
Circulation Research. 80:655-664
Abstract The regulatory myosin light chain (MLC) regulates contraction in smooth muscle. However, its function in striated muscle remains obscure, and the different functional activities of the various isoforms that are expressed in the mammalian hea
Publikováno v:
Journal of Clinical Investigation. 98:167-176
To examine the role of alterations in myofibrillar function in human dilated cardiomyopathies, we determined isometric tension-calcium relations in permeabilized myocytesized myofibrillar preparations (n = 16) obtained from left ventricular biopsies
Autor:
Andrew J. Waclawik, Kevin P. Campbell, Paul J. Lewandoski, Yoshihida Sunada, Barend P. Lotz, Scott H. Buck, Ricardo Fadic
Publikováno v:
New England Journal of Medicine. 334:362-366
Cardiac muscle is commonly affected in muscular dystrophies.1–4 X-linked Duchenne's muscular dystrophy and Becker's muscular dystrophy are caused by mutations in the gene encoding dystrophin,5,6 a membrane cytoskeletal protein.7 In skeletal and car
Publikováno v:
Progress in Pediatric Cardiology. 3:94-99
DiGeorge syndrome refers to a rare constellation of cardiac, parathyroid, thymic, and facial anomalies attributed to disruption of the interaction of premigratory neural crest cells with endodermal pharyngeal pouch cells. Prototypic cases are recogni
Autor:
Evelyn Okediji, Sidney Fleischer, Frank Scott, Scott H. Buck, Niki L. Oquist, Richard D. Olson, Robert J. Boucek
Publikováno v:
Journal of Molecular and Cellular Cardiology. 25:249-259
Anthracyclines, such as doxorubicin (DOX), are important cancer chemotherapeutic agents that are cardiotoxic. The mechanism for the cardiotoxicity is not well-defined. Recent studies have concluded that anthracyclines release calcium (Ca2+) from memb
Autor:
Scott H. Buck
Publikováno v:
Netter's Cardiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddaca00dc547b2788e45ea00e2e886ef
https://doi.org/10.1016/b978-1-4377-0637-6.00054-4
https://doi.org/10.1016/b978-1-4377-0637-6.00054-4