Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Scott Gehler"'
Autor:
Aaron A. Jones, Scott Gehler
Publikováno v:
Integrative Cancer Therapies, Vol 19 (2020)
Naturally occurring flavonoids, such as acacetin and pinostrobin, disrupt a wide range of processes during tumor progression, such as cell proliferation, apoptosis, and angiogenesis. Although the antiproliferative and antiapoptotic effects of acaceti
Externí odkaz:
https://doaj.org/article/b07656339d824a5187fa54f451118018
Publikováno v:
International Journal of Breast Cancer, Vol 2017 (2017)
Interactions between integrin-mediated adhesions and the extracellular matrix (ECM) are important regulators of cell migration and spreading. However, mechanisms by which extracellular ligands regulate cell migration and spreading in response to chan
Externí odkaz:
https://doaj.org/article/be689cef94574051a796c1f458b4ef0b
Publikováno v:
Critical Reviews in Eukaryotic Gene Expression. 23:139-157
Cell transformation and tumor progression involves a common set of acquired capabilities, including increased proliferation, failure of cell death, self-sufficiency in growth, angiogenesis, and tumor cell invasion and metastasis (1). The stromal envi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c64e6f8f4efef4243006924928d3d3a
https://doi.org/10.1615/critreveukargeneexpr.2013006647
https://doi.org/10.1615/critreveukargeneexpr.2013006647
Autor:
Kevin W. Eliceiri, Valerie M. Weaver, David A. Calderwood, Jennifer L. Leight, Patricia J. Keely, Michele A. Wozniak, Yatish Lad, Massimiliano Baldassarre, Scott Gehler, Kristin M. Riching
Publikováno v:
Molecular Biology of the Cell. 20:3224-3238
The physical properties of the extracellular matrix (ECM) regulate the behavior of several cell types; yet, mechanisms by which cells recognize and respond to changes in these properties are not clear. For example, breast epithelial cells undergo duc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f56e0bfa2bdb5cb63531078832730f
https://doi.org/10.1091/mbc.e08-12-1186
https://doi.org/10.1091/mbc.e08-12-1186
Publikováno v:
The Journal of Neuroscience. 24:10741-10749
The molecular mechanisms by which neurotrophins regulate growth cone motility are not well understood. This study investigated the signaling involved in transducing BDNF-induced increases of filopodial dynamics. Our results indicate that BDNF regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6fbd81b1c4be1caad97e1707b6eb3d
https://doi.org/10.1523/jneurosci.2836-04.2004
https://doi.org/10.1523/jneurosci.2836-04.2004
Publikováno v:
Methods in enzymology. 426
There has been much recent interest in working with cells cultured in three-dimensional (3D) matrices to better model the properties of the extracellular matrix environment found in vivo. However, working within 3D matrices adds several difficulties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5f6a7596b6b76516cfa7fb8b60d3175
https://pubmed.ncbi.nlm.nih.gov/17697878
https://pubmed.ncbi.nlm.nih.gov/17697878
There has been much recent interest in working with cells cultured in three-dimensional (3D) matrices to better model the properties of the extracellular matrix environment found in vivo. However, working within 3D matrices adds several difficulties
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ceb39f50ba9bd94168f06303ac06b433
https://doi.org/10.1016/s0076-6879(07)26002-1
https://doi.org/10.1016/s0076-6879(07)26002-1
Publikováno v:
Journal of neurobiology. 66(2)
Rho family GTPases have important roles in mediating the effects of guidance cues and growth factors on the motility of neuronal growth cones. We previously showed that the neurotrophin BDNF regulates filopodial dynamics on growth cones of retinal ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8655318bfa06de1d3f60fe6b6a67d68
https://pubmed.ncbi.nlm.nih.gov/16215999
https://pubmed.ncbi.nlm.nih.gov/16215999
The mechanisms by which neurotrophins regulate growth cone motility are unclear. We investigated the role of the p75 neurotrophin receptor (p75NTR) in mediating neurotrophin-induced increases in filopodial length. Our data demonstrate that neurotroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1f2a6be646c063695516f219e94cec
https://europepmc.org/articles/PMC6729430/
https://europepmc.org/articles/PMC6729430/