Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Scott G. Holmes"'
Publikováno v:
G3 Genes|Genomes|Genetics. 12
Progression through meiosis is associated with significant reorganization of chromosome structure, regulated in part by changes in histones and chromatin. Prior studies observed defects in meiotic progression in yeast strains lacking the linker histo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1243aef337efc418aee0dfe4a2c7f24
https://doi.org/10.1093/g3journal/jkac128
https://doi.org/10.1093/g3journal/jkac128
Autor:
Alison E Ringel, Rebecca Ryznar, Hannah Picariello, Kuan-lin Huang, Asmitha G Lazarus, Scott G Holmes
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003871 (2013)
Sir2 is an NAD(+)-dependent histone deacetylase required to mediate transcriptional silencing and suppress rDNA recombination in budding yeast. We previously identified Tdh3, a glyceraldehyde 3-phosphate dehydrogenase (GAPDH), as a high expression su
Externí odkaz:
https://doaj.org/article/6e204a01a3a6459ab0dd232d14d0f206
Publikováno v:
The FASEB Journal. 34:1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393381c63bdf62590d848708927fdf29
https://doi.org/10.1096/fasebj.2020.34.s1.06049
https://doi.org/10.1096/fasebj.2020.34.s1.06049
Publikováno v:
Molecular and Cellular Biology. 33:3473-3481
H2A.Z is a highly conserved variant of histone H2A with well-characterized roles in transcriptional regulation. We previously reported that H2A.Z and Mcd1, a subunit of the cohesin complex, regulate the establishment of transcriptional silencing at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a8421b3eadc4fb652623ffaca46c739
https://doi.org/10.1128/mcb.00162-12
https://doi.org/10.1128/mcb.00162-12
Publikováno v:
Molecular and Cellular Biology. 32:2784-2793
Epigenetic mechanisms maintain the specific characteristics of differentiated cells by ensuring the inheritance of gene expression patterns through DNA replication and mitosis. We examined the mechanism of epigenetic inheritance of Sir protein-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05be30972141e4341437b953fb70cd3
https://doi.org/10.1128/mcb.06399-11
https://doi.org/10.1128/mcb.06399-11
Autor:
Scott G. Holmes
Publikováno v:
Cell Cycle. 16:1485-1486
Condensins are highly conserved protein complexes that regulate chromosome organization, affecting transcription and preparing chromosomes for mitosis.1 Experiments conducted in budding yeast cells...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b17c62aeaf7c96ae9a44a33b3d3ffd73
https://doi.org/10.1080/15384101.2017.1345234
https://doi.org/10.1080/15384101.2017.1345234
Autor:
Scott G. Holmes, Asmitha G. Lazarus
Publikováno v:
Genetics. 187:425-439
Numerous studies have determined that the establishment of Sir protein-dependent transcriptional silencing in yeast requires progression through the cell cycle. In our study we examined the cell cycle requirement for the establishment of silencing at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cbffbb9394bdd7c105a7b327187dce
https://doi.org/10.1534/genetics.110.124099
https://doi.org/10.1534/genetics.110.124099
Publikováno v:
Genetics. 187:89-104
The establishment of transcriptional silencing in Saccharomyces cerevisiae requires progression through the cell cycle. We have previously found that transit through M-phase is necessary and sufficient to establish silencing at telomeres following in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f40b9bad93ab4b92397c3290764538b
https://doi.org/10.1534/genetics.110.123844
https://doi.org/10.1534/genetics.110.123844
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3ac83672226ff16da864ac17cce32d4
https://doi.org/10.1096/fasebj.29.1_supplement.709.4
https://doi.org/10.1096/fasebj.29.1_supplement.709.4
Autor:
Scott G. Holmes, Jason C. Tanny, Danesh Moazed, Mirela Matecic, Merrit Hickman, Kristen Martins-Taylor
Publikováno v:
Genetics. 173:1939-1950
The establishment of transcriptional silencing in yeast requires cell-cycle progression, but the nature of this requirement is unknown. Sir2 is a protein deacetylase that is required for gene silencing in yeast. We have used temperature-sensitive all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::783d38818d0d95d600d7b15060758c70
https://doi.org/10.1534/genetics.106.055491
https://doi.org/10.1534/genetics.106.055491