Zobrazeno 1 - 10
of 349
pro vyhledávání: '"Scott G. Filler"'
Autor:
Tingting Zhou, Norma V. Solis, Michaela Marshall, Qing Yao, Rachel Garleb, Mengli Yang, Eric Pearlman, Scott G. Filler, Haoping Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Patients with decreased levels of CD18 (β2 integrins) suffer from life-threatening bacterial and fungal infections. CD11b, the α subunit of integrin CR3 (CD11b/CD18, αMβ2), is essential for mice to fight against systemic Candida albicans
Externí odkaz:
https://doaj.org/article/0f81f176012742c69ace6098249d696b
Autor:
Rajesh Parmar, Harry Pickering, Richard Ahn, Maura Rossetti, David W. Gjertson, Felicia Ruffin, Liana C. Chan, Vance G. Fowler, Michael R. Yeaman, Elaine F. Reed, MRSA Systems Immunology Group, Arnold S. Bayer, Yu-Ling Chang, Scott G. Filler, Vance G. Fowler Jr., David Gjertson, Alexander Hoffmann, Felix Mba Medie, Tsuyoshi Mikkaichi, Simon Mitchell, Yan Qin, Batu K. Sharma-Kuinkel, Katherine Sheu, Joshua Thaden, Alan J. Waring, Yan Q. Xiong, Ying Zheng, Michael R. Yeaman.
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionStaphylococcus aureus bacteremia (SAB) is a life-threatening infection particularly involving methicillin-resistant S. aureus (MRSA). In contrast to resolving MRSA bacteremia (RB), persistent MRSA bacteremia (PB) blood cultures remain pos
Externí odkaz:
https://doaj.org/article/a79666f3f3d748269414ccca0d43d820
Autor:
Virginia E. Glazier, Juraj Kramara, Tomye Ollinger, Norma V. Solis, Robert Zarnowski, Rohan S. Wakade, Min-Ju Kim, Gabriel J. Weigel, Shen-Huan Liang, Richard J. Bennett, Melanie Wellington, David R. Andes, Mark A. Stamnes, Scott G. Filler, Damian J. Krysan
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Candida albicans is a diploid human fungal pathogen that displays significant genomic and phenotypic heterogeneity over a range of virulence traits and in the context of a variety of environmental niches. Here, we show that the effect of Rob
Externí odkaz:
https://doaj.org/article/d9d88ba2cedc4442aa5ec5ea0648059b
Autor:
Zhangyu Cheng, Caroline Stefani, Thomas Skillman, Aleksandra Klimas, Aramchan Lee, Emma F. DiBernardo, Karina Mueller Brown, Tatyana Milman, Yuhong Wang, Brendan R. Gallagher, Katherine Lagree, Bhanu P. Jena, Jose S. Pulido, Scott G. Filler, Aaron P. Mitchell, N. Luisa Hiller, Adam Lacy‐Hulbert, Yongxin Zhao
Publikováno v:
Advanced Science, Vol 10, Iss 30, Pp n/a-n/a (2023)
Abstract Super‐resolution optical imaging tools are crucial in microbiology to understand the complex structures and behavior of microorganisms such as bacteria, fungi, and viruses. However, the capabilities of these tools, particularly when it com
Externí odkaz:
https://doaj.org/article/f62ce5c239f04a70b2f59e74b0c6f6b3
Autor:
Hong Liu, Jianfeng Lin, Quynh T. Phan, Fabrice N. Gravelat, Donald C. Sheppard, Scott G. Filler
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT During the initiation of invasive aspergillosis, inhaled Aspergillus fumigatus conidia are deposited on the epithelial cells lining the bronchi, terminal bronchioles, and alveoli. While the interactions of A. fumigatus with bronchial and typ
Externí odkaz:
https://doaj.org/article/ec3c38c7baaa4fb9b276cb2d53534c77
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Invasive aspergillosis is initiated when Aspergillus fumigatus adheres to and invades the pulmonary epithelial cells that line the airways and alveoli. To gain deeper insight into how pulmonary epithelial cells respond to A. fumigatus invasi
Externí odkaz:
https://doaj.org/article/174ba912379d47f2b76101e0e36c1c74
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT Aspergillus fumigatus is an environmental fungus that can cause life-threatening pulmonary disease. Infections initiate when conidia are inhaled and land deep inside the small airways and alveoli of the lungs, where they interact with epithe
Externí odkaz:
https://doaj.org/article/e749b9b12c92426190157567cdf16429
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Nrg1 is a repressor of hypha formation and hypha-associated gene expression in the fungal pathogen Candida albicans. It has been well studied in the genetic background of the type strain SC5314. Here, we tested Nrg1 function in four other di
Externí odkaz:
https://doaj.org/article/193b9cb1b897468d99554e31cd075ed8
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Candida albicans is a commensal of the human gastrointestinal tract and a common cause of human fungal disease, including mucosal infections, such as oropharyngeal candidiasis and disseminated infections of the bloodstream and deep organs. W
Externí odkaz:
https://doaj.org/article/c2cf4858d20e4a1d8965a9f69aa2debe
Autor:
Anupam Sharma, Norma V. Solis, Manning Y. Huang, Frederick Lanni, Scott G. Filler, Aaron P. Mitchell
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Biofilm and hypha formation are central to virulence of the fungal pathogen Candida albicans. The G1 cyclin gene HGC1 is required for hypha formation under diverse in vitro and in vivo growth conditions. Hgc1 is required for disseminated inf
Externí odkaz:
https://doaj.org/article/f8856a278ab24cf4b1a1150e94d41e42