Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Scott F. Rusin"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 5 (2017)
Protein phosphorylation is a crucial regulatory mechanism that controls many aspects of cellular signaling. Casein kinase 2 (CK2), a constitutively expressed and active kinase, plays key roles in an array of cellular events including transcription an
Externí odkaz:
https://doaj.org/article/e4c986185e5f4400a98135ad70bb330d
Autor:
Sara M Nowinski, Ashley Solmonson, Scott F Rusin, J Alan Maschek, Claire L Bensard, Sarah Fogarty, Mi-Young Jeong, Sandra Lettlova, Jordan A Berg, Jeffrey T Morgan, Yeyun Ouyang, Bradley C Naylor, Joao A Paulo, Katsuhiko Funai, James E Cox, Steven P Gygi, Dennis R Winge, Ralph J DeBerardinis, Jared Rutter
Publikováno v:
eLife, Vol 9 (2020)
Cells harbor two systems for fatty acid synthesis, one in the cytoplasm (catalyzed by fatty acid synthase, FASN) and one in the mitochondria (mtFAS). In contrast to FASN, mtFAS is poorly characterized, especially in higher eukaryotes, with the major
Externí odkaz:
https://doaj.org/article/f28d705b3f05490b91c7e479d58b568b
Publikováno v:
bioRxiv
Protein phosphorylation is an essential regulatory mechanism that controls most cellular processes, including cell cycle progression, cell division, and response to extracellular stimuli, among many others, and is deregulated in many diseases. Protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600b9aa59797ed30000748d0f0c92d31
https://europepmc.org/articles/PMC10055397/
https://europepmc.org/articles/PMC10055397/
Publikováno v:
eLife, Vol 6 (2017)
The fidelity of chromosome segregation in mitosis is safeguarded by the precise regulation of kinetochore microtubule (k-MT) attachment stability. Previously, we demonstrated that Cyclin A/Cdk1 destabilizes k-MT attachments to promote faithful chromo
Externí odkaz:
https://doaj.org/article/ccbb4531ee054d55a04a4b47cd938ba7
Autor:
Zhongle Liu, Lawrence C. Myers, Jeffrey M. Hollomon, Smith Ak, Deborah A. Hogan, Nicole P. Jenkins, Scott F. Rusin, Katja Koeppen, Arminja N. Kettenbach
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 18, Iss 1, p e1009622 (2022)
PLoS Genetics, Vol 18, Iss 1, p e1009622 (2022)
Ssn3, also known as Cdk8, is a member of the four protein Cdk8 submodule within the multi-subunit Mediator complex involved in the co-regulation of transcription. In Candida albicans, the loss of Ssn3 kinase activity affects multiple phenotypes inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38219b429c875eb2f7d778e5d986133
https://doi.org/10.1101/2021.06.10.447844
https://doi.org/10.1101/2021.06.10.447844
Autor:
Jordan A. Berg, Bradley C. Naylor, Scott F. Rusin, Sarah Fogarty, Ashley Solmonson, Sandra Lettlova, Jeffrey T. Morgan, Dennis R. Winge, Katsuhiko Funai, Sara M. Nowinski, James E. Cox, Ralph J. DeBerardinis, Steven P. Gygi, Jared Rutter, J. Alan Maschek, Mi Young Jeong, Yeyun Ouyang, Claire L. Bensard, Joao A. Paulo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::410eb50b6a3b9a2a64cad604428198f4
https://doi.org/10.7554/elife.58041.sa2
https://doi.org/10.7554/elife.58041.sa2
Autor:
Yeyun Ouyang, Ashley Solmonson, Claire L. Bensard, James E. Cox, J. Alan Maschek, Sara M. Nowinski, Scott F. Rusin, Bradley C. Naylor, Jordan A. Berg, Ralph J. DeBerardinis, Katsuhiko Funai, Joao A. Paulo, Dennis R. Winge, Sandra Lettlova, Jared Rutter, Steven P. Gygi, Mi Young Jeong, Jeffrey T. Morgan, Sarah Fogarty
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Cells harbor two systems for fatty acid synthesis, one in the cytoplasm (catalyzed by fatty acid synthase, FASN) and one in the mitochondria (mtFAS). In contrast to FASN, mtFAS is poorly characterized, especially in higher eukaryotes, with the major
Autor:
J. Alan Maschek, Ashley Solmonson, Joao A. Paulo, Sarah Fogarty, Jordan A. Berg, Dennis R. Winge, Bradley C. Naylor, Steven P. Gygi, Katsuhiko Funai, Mi Young Jeong, Jeffrey T. Morgan, Claire L. Bensard, James E. Cox, Yeyun Ouyang, Sara M. Nowinski, Scott F. Rusin, Sandra Lettlova, Ralph J. DeBerardinis, Jared Rutter
Cells harbor two systems for fatty acid synthesis, one in the cytoplasm (catalyzed by fatty acid synthase, FASN) and one in the mitochondria (mtFAS). In contrast to FASN, mtFAS is poorly characterized, especially in higher eukaryotes, with the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d3b560c3a1e89632540a450657443b
https://doi.org/10.1101/2020.05.09.086199
https://doi.org/10.1101/2020.05.09.086199
Publikováno v:
J Proteome Res
Phosphorylation is a post-translational modification with a vital role in cellular signaling. Isobaric labeling-based strategies, such as tandem mass tags (TMT), can measure the relative phosphorylation states of peptides in a multiplexed format. How
Autor:
Samyabrata Bhaduri, Rahul Karnik, Matthew M. Weiss, Scott F. Rusin, Alice McDonald, Michele Mayo, Duncan Walker, Kirti Sharma, Christine Klaus
Publikováno v:
Cancer Research. 81:LB118-LB118
Relapsed/refractory DLBCL remains an incurable disease, and single-agent therapies typically show low response rates and/or transient clinical responses. Oncogenic MYD88 mutations occur in ~25% of DLBCL and drive constitutive NFkB activation, promoti