Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Scott Eric Woodman"'
Autor:
Shiao-Pei S. Weathers, Haifeng Zhu, Mark Knafl, Ashish Damania, Carlos Kamiya-Matsuoka, Rebecca A. Harrison, Larry Lyons, Cindy Yun, Walter C. Darbonne, Monica Loghin, Marta Penas-Prado, Nazanin Majd, W. K. Alfred Yung, Barbara Jane O'Brien, Ignacio Ivan Wistuba, Andrew Futreal, Jennifer Ann Wargo, Nadim J. Ajami, Scott Eric Woodman, John Frederick de Groot
Publikováno v:
Journal of Clinical Oncology. 40:2006-2006
2006 Background: Checkpoint inhibitor (CPI) therapy has demonstrated overall limited efficacy in the treatment of GBM. Sixty newly diagnosed GBM patients unselected for MGMT status underwent treatment with concurrent atezolizumab with radiation thera
Autor:
Michael White, Christopher P. Vellano, Miles Cameron Andrews, Russell G. Witt, Manoj Chelvanambi, Jennifer Leigh McQuade, Elizabeth M. Burton, Yanshuo Chu, Matthew J Lastrapes, Mike R. Lau, Hiya Banerjee, Alexander J. Lazar, Michael A. Davies, Scott Eric Woodman, Linghua Wang, Amy E. Moran, Georgina V. Long, Timothy Heffernan, Joe R. Marszalek, Jennifer Ann Wargo
Publikováno v:
Journal of Clinical Oncology. 40:9523-9523
9523 Background: Treatment with BRAF+/-MEK inhibition (BRAF+/-MEKi) has revolutionized treatment in melanoma and other cancers, but resistance is common and innovative treatment strategies are needed. Sexual dimorphism in response to BRAF+/-MEKi have
Autor:
Elizabeth M. Burton, Timothy Woody, Isabella Claudia Glitza, Rodabe Navroze Amaria, Emily Zhi-Yun Keung, Adi Diab, Sapna Pradyuman Patel, Michael K.K. Wong, Cassian Yee, Patrick Hwu, Jennifer Leigh McQuade, Scott Eric Woodman, Michael T. Tetzlaff, Michael A. Davies, Jennifer Ann Wargo, Kunal Rai, Hussein Abdul-Hassan Tawbi
Publikováno v:
Journal of Clinical Oncology. 37:9560-9560
9560 Background: Immune checkpoint blockade (ICB) have improved survival for many pts with MM, offering durable responses in up to 35% of pts, but many have short-lived or no response ( > 40%). A potential immune escape mechanism is the subversion of
Autor:
Alex W. Cohen, Stephen M. Factor, Scott Eric Woodman, Baiyu Tang, Linda A. Jelicks, David S. Park, Andrea Pereira De Souza, David E. Gutstein, Michael P. Lisanti, Herbert B. Tanowitz
Publikováno v:
Magnetic Resonance Imaging. 23:61-68
Caveolin-1 and caveolin-3 are expressed in the mammalian heart. Mice deficient in caveolin 1 or 3 exhibit cardiac abnormalities including left ventricular hypertrophy and reduced fractional shortening. Cardiac imaging technologies such as transthorac
Publikováno v:
Neurology. 62:538-543
The caveolin-3 protein is expressed exclusively in muscle cells. Caveolin-3 expression is sufficient to form caveolae-sarcolemmal invaginations that are 50 to 100 nm in diameter. Monomers of caveolin-3 oligomerize to form high molecular mass scaffold
Autor:
Stephen M. Factor, Amanda North, William Schubert, Robert G. Russell, Michelle W.-C. Cheung, Guy Lagaud, George J. Christ, Moses Tarr, Ghada. S. Hassan, Michael P. Lisanti, Carolyn Marks, Scott Eric Woodman
Publikováno v:
Journal of Urology. 171:950-957
Caveolae are flask-shaped invaginations of the plasma membrane formed by the oligomerization of caveolins. Because only smooth muscle contains all caveolin (Cav) family members (Cav-1, 2 and 3), we examined the contribution of each caveolin to urogen
Autor:
Michael P. Lisanti, Carlo Minetti, Federica Sotgia, Scott Eric Woodman, Franco Capozza, Philipp E. Scherer, Robert G. Kemp, Gloria Bonuccelli
Publikováno v:
The American Journal of Pathology. 163:2619-2634
Previous co-immunoprecipitation studies have shown that endogenous PFK-M (phosphofructokinase, muscle-specific isoform) associates with caveolin (Cav)-3 under certain metabolic conditions. However, it remains unknown whether Cav-3 expression is requi
Autor:
Scott Eric Woodman, Federica Sotgia, Carlo Minetti, Philipp E. Scherer, Michael P. Lisanti, Gloria Bonuccelli, Franco Capozza
Publikováno v:
American Journal of Physiology-Cell Physiology. 285:C1150-C1160
Four different phenotypes have been associated with CAV3 mutations: limb girdle muscular dystrophy-1C (LGMD-1C), rippling muscle disease (RMD), and distal myopathy (DM), as well as idiopathic and familial hyperCKemia (HCK). Detailed molecular charact
Autor:
William Schubert, Anthony W. Ashton, Terence M. Williams, Terry P. Combs, Freddy A. Medina, Hyangkyu Lee, Jeffrey B. Wyckoff, Michael P. Lisanti, Scott Eric Woodman
Publikováno v:
The American Journal of Pathology. 162:2059-2068
Recent studies have shown that caveolin-1 (Cav-1) plays an important role as a regulator of angiogenesis in vitro. Here, we use Cav-1 knockout (KO) mice as a model system to examine the in vivo relevance of these findings. A primary mediator of angio
Autor:
Michael P. Lisanti, Stephen M. Factor, Jamshid Shirani, Scott Eric Woodman, Richard N. Kitsis, Terrence M. Williams, Robert G. Russell, David S. Park, Linda A. Jelicks, Herbert B. Tanowitz, Louis M. Weiss, Baiyu Tang, Andrea Pereira De Souza, Vitaliy Shtutin, Madhulika Chandra, Alex W. Cohen
Publikováno v:
American Journal of Physiology-Cell Physiology. 284:C457-C474
Recently, development of a caveolin-1-deficient (Cav-1 null) mouse model has allowed the detailed analysis of caveolin-1's function in the context of a whole animal. Interestingly, we now report that the hearts of Cav-1 null mice are markedly abnorma