Zobrazeno 1 - 10
of 292
pro vyhledávání: '"Scott Edwards"'
Publikováno v:
Frontiers in Education, Vol 9 (2024)
IntroductionAlcohol use disorder (AUD) is a psychiatric disease that affects approximately 10% of the population. Individuals suffer from a myriad of causes and consequences of AUD, and team-based management of patients is often required for given th
Externí odkaz:
https://doaj.org/article/913a84ede2e74e569dcdf3043fa5a0f8
Autor:
Hernan A. Bazan, Surjyadipta Bhattacharjee, Madigan M. Reid, Bokkyoo Jun, Connor Polk, Madeleine Strain, Linsey A. St Pierre, Neehar Desai, Patrick W. Daly, Jessica A. Cucinello-Ragland, Scott Edwards, Javier Recio, Julio Alvarez-Builla, James J. Cai, Nicolas G. Bazan
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-35 (2024)
Abstract Safe and effective pain management is a critical healthcare and societal need. The potential for acute liver injury from paracetamol (ApAP) overdose; nephrotoxicity and gastrointestinal damage from chronic non-steroidal anti-inflammatory dru
Externí odkaz:
https://doaj.org/article/e955fc7d7b3b4d97b98770099763f826
Autor:
Sandeep R. Sehdev, Nigel S. B. Rawson, Olexiy I. Aseyev, Catriona J. Buick, Marcus O. Butler, Scott Edwards, Sharlene Gill, Joanna M. Gotfrit, Cyrus C. Hsia, Rosalyn A. Juergens, Mita Manna, Joy S. McCarthy, Som D. Mukherjee, Stephanie L. Snow, Silvana Spadafora, David J. Stewart, Jason R. Wentzell, Ralph P. W. Wong, Pawel G. Zalewski
Publikováno v:
Current Oncology, Vol 31, Iss 4, Pp 1803-1816 (2024)
Patient access to new oncology drugs in Canada is only possible after navigating multiple sequential systemic checkpoints for national regulatory approval, health technology assessment (HTA) and collective government price negotiation. These steps de
Externí odkaz:
https://doaj.org/article/3be7b57ba6b54e2e8cadf719163522c8
Autor:
Katarzyna J. Jerzak, Nathaniel Bouganim, Christine Brezden-Masley, Scott Edwards, Karen Gelmon, Jan-Willem Henning, John F. Hilton, Sandeep Sehdev
Publikováno v:
Current Oncology, Vol 30, Iss 6, Pp 5425-5447 (2023)
The approval of CDK4/6 inhibitors has dramatically improved care for the treatment of HR+/HER2– advanced breast cancer, but navigating the rapidly-expanding treatment evidence base is challenging. In this narrative review, we provide best-practice
Externí odkaz:
https://doaj.org/article/77349f80392f48ffb5d426cf815358ca
Autor:
Mahum T. Siddiqi, Dhruba Podder, Amanda R. Pahng, Alexandria C. Athanason, Tali Nadav, Chelsea Cates-Gatto, Max Kreifeldt, Candice Contet, Amanda J. Roberts, Scott Edwards, Marisa Roberto, Florence P. Varodayan
Publikováno v:
Addiction Neuroscience, Vol 9, Iss , Pp 100137- (2023)
Alcohol use disorder (AUD) produces cognitive deficits, indicating a shift in prefrontal cortex (PFC) function. PFC glutamate neurotransmission is mostly mediated by α-amino-3‑hydroxy-5-methyl-4-isoxazolepropionic acid-type ionotropic receptors (A
Externí odkaz:
https://doaj.org/article/06eb8a910c9d45f59ac89c917ba77f9d
Autor:
Scott Edwards, Tekeda F. Ferguson, Sonia Gasparini, Donald E. Mercante, Patricia E. Molina, Tina P. Gunaldo
Publikováno v:
BMC Medical Education, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Effective screening of alcohol use and prevention of alcohol use disorder (AUD) requires the continuous preparation of educated and confident providers across all health professions who will ideally work in close collaboration in
Externí odkaz:
https://doaj.org/article/6fcfa740d53d4e90827855ca62dbebb9
Autor:
Liang Liu, Lili Yu, Shaoyuan Wu, Jonathan Arnold, Christopher Whalen, Charles Davis, Scott Edwards
Publikováno v:
Frontiers in Ecology and Evolution, Vol 11 (2023)
Accurate reconstruction of species trees often relies on the quality of input gene trees estimated from molecular sequences. Previous studies suggested that if the sequence length is fixed, the maximum likelihood may produce biased gene trees which s
Externí odkaz:
https://doaj.org/article/532ee409f71a42fbb1a4ef315300aba6
Autor:
Jessica C. Wise, Kristopher J. Hughes, Scott Edwards, Glenn A. Jacobson, Christian K. Narkowicz, Sharanne L. Raidal
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 35, Iss 1, Pp 620-631 (2021)
Abstract Background Omeprazole preparations vary in bioavailability in horses. Hypothesis/Objectives To characterize the pharmacokinetics and pharmacodynamics of an existing enteric‐coated oral omeprazole paste (REF) and a novel, in‐feed, enteric
Externí odkaz:
https://doaj.org/article/6a29073ee2124ee89504ac73dc6fadb9
Publikováno v:
Frontiers in Physiology, Vol 12 (2022)
At-risk alcohol use is a significant risk factor associated with multisystemic pathophysiological effects leading to multiorgan injury and contributing to 5.3% of all deaths worldwide. The alcohol-mediated cellular and molecular alterations are parti
Externí odkaz:
https://doaj.org/article/d91759b058b44254bfae6264ae22fefe
Publikováno v:
Neurobiology of Pain, Vol 8, Iss , Pp 100052- (2020)
Alcohol use disorder (AUD) is a chronic, relapsing psychiatric disorder that is characterized by the emergence of negative affective states. The transition from recreational, limited intake to uncontrolled, escalated intake is proposed to involve a t
Externí odkaz:
https://doaj.org/article/e4be2c0521124a84b4e6697cd8ae514d