Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Scott E. Nelson"'
Autor:
Deo R. Singh, Scott E. Nelson, Abigail S. Pawelski, Juan A. Cantres-Velez, Alisha S. Kansra, Nicholas P. Pauly, Jillian A. Bristol, Mitchell Hayes, Makoto Ohashi, Alejandro Casco, Denis Lee, Stuart A. Fogarty, Paul F. Lambert, Eric C. Johannsen, Shannon C. Kenney
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10 (2022)
Differentiated epithelial cells are an important source of infectious EBV virions in human saliva, and latent Epstein-Barr virus (EBV) infection is strongly associated with the epithelial cell tumor, nasopharyngeal carcinoma (NPC). However, it has be
Externí odkaz:
https://doaj.org/article/658ddf74678b4b0db97b55b8979ae5f4
Autor:
Jillian A. Bristol, Joshua Brand, Makoto Ohashi, Mark R. Eichelberg, Alejandro Casco, Scott E. Nelson, Mitchell Hayes, James C. Romero-Masters, Dana C. Baiu, Jenny E. Gumperz, Eric C. Johannsen, Huy Q. Dinh, Shannon C. Kenney
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4 (2022)
Humans are infected with two types of EBV (Type 1 (T1) and Type 2 (T2)) that differ substantially in their EBNA2 and EBNA 3A/B/C latency proteins and have different phenotypes in B cells. T1 EBV transforms B cells more efficiently than T2 EBV in vitr
Externí odkaz:
https://doaj.org/article/935aade5bcd54316b7fdae726ce22c18
Autor:
Jillian A Bristol, Scott E Nelson, Makoto Ohashi, Alejandro Casco, Mitchell Hayes, Erik A Ranheim, Abigail S Pawelski, Deo R Singh, Daniel J Hodson, Eric C Johannsen, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012132 (2024)
Epstein-Barr virus (EBV) is an important cause of human lymphomas, including Burkitt lymphoma (BL). EBV+ BLs are driven by Myc translocation and have stringent forms of viral latency that do not express either of the two major EBV oncoproteins, EBNA2
Externí odkaz:
https://doaj.org/article/43ac485e6f8547838097af8a167f2b00
Autor:
Deo R. Singh, Scott E. Nelson, Abigail S. Pawelski, Alisha S. Kansra, Stuart A. Fogarty, Jillian A. Bristol, Makoto Ohashi, Eric C. Johannsen, Shannon C. Kenney
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Latent Epstein–Barr virus (EBV) infection promotes undifferentiated nasopharyngeal carcinomas (NPCs) in humans, but the mechanism(s) for this effect has been difficult to study because EBV cannot transform normal epithelial cells in vitro and the E
Autor:
DeannaLee M. Beauvais, Scott E. Nelson, Kristin M. Adams, Noah A. Stueven, Oisun Jung, Alan C. Rapraeger
Publikováno v:
The Journal of biological chemistry. 298(6)
Epidermal growth factor receptor (EGFR) is a causal factor in carcinoma, yet many carcinoma patients are resistant to EGFR inhibitors. Potential insight into this resistance stems from prior work that showed EGFR in normal epithelial cells docks to t
Autor:
Jillian A. Bristol, Joshua Brand, Makoto Ohashi, Mark R. Eichelberg, Alejandro Casco, Scott E. Nelson, Mitchell Hayes, James C. Romero-Masters, Dana C. Baiu, Jenny E. Gumperz, Eric C. Johannsen, Huy Q. Dinh, Shannon C. Kenney
Publikováno v:
PLoS pathogens. 18(4)
Humans are infected with two types of EBV (Type 1 (T1) and Type 2 (T2)) that differ substantially in their EBNA2 and EBNA 3A/B/C latency proteins and have different phenotypes in B cells. T1 EBV transforms B cells more efficiently than T2 EBV in vitr
Autor:
Makoto Ohashi, Nicholas P. Pauly, Jillian A. Bristol, Nicholas Van Sciver, Shannon C. Kenney, Scott E. Nelson, Eric Johannsen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009783 (2021)
PLoS Pathogens
PLoS Pathogens
The Epstein-Barr virus (EBV) human herpesvirus is associated with B-cell and epithelial-cell malignancies, and both the latent and lytic forms of viral infection contribute to the development of EBV-associated tumors. Here we show that the Hippo sign
Autor:
Shannon C. Kenney, Jenny E. Gumperz, Scott E. Nelson, Eric Johannsen, Nicholas A. Zumwalde, Reza Djavadian, Mitchell Hayes, Mark R. Eichelberg, Erik A. Ranheim, Makoto Ohashi, Shidong Ma, James C. Romero-Masters, Jillian A. Bristol
Publikováno v:
J Virol
Epstein-Barr virus (EBV) causes B cell lymphomas and transforms B cells in vitro. The EBV protein EBNA3A collaborates with EBNA3C to repress p16 expression and is required for efficient transformation in vitro. An EBNA3A deletion mutant EBV strain wa
Autor:
Mark R. Eichelberg, Chunrong Li, Nicholas Van Sciver, Makoto Ohashi, Jillian A. Bristol, Eric Johannsen, Scott E. Nelson, Shane M. Huebner, Rona S. Scott, James C. Romero-Masters, Mitchell Hayes, Erik A. Ranheim, Shannon C. Kenney
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 6, p e1008590 (2020)
PLoS Pathogens, Vol 16, Iss 6, p e1008590 (2020)
EBV transforms B cells in vitro and causes human B-cell lymphomas including classical Hodgkin lymphoma (CHL), Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL). The EBV latency protein, EBNA2, transcriptionally activates the promoters o
Autor:
Alan C. Rapraeger, Richard A. Anderson, Denis Lee, Noah Stueven, Kristin Short, Paul F. Lambert, DeannaLee M. Beauvais, Scott E. Nelson, Oisun Jung
Syndecan-4 (Sdc4) organizes a complex of receptors consisting of its homologue, Sdc2, the receptor tyrosine kinases EGFR and MST1R/RON, and the laminin-binding α3β1 and α6β4 integrins that depends on a docking site within its extracellular domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8020fddd516f7bed1a6b331956eaae0b