Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Scott E. Morgan"'
Publikováno v:
Anesthesiology. 105:892-897
Background A new eight-wavelength pulse oximeter is designed to measure methemoglobin and carboxyhemoglobin, in addition to the usual measurements of hemoglobin oxygen saturation and pulse rate. This study examines this device's ability to measure dy
Publikováno v:
Anesthesiology. 87:308-316
Background Increased carboxyhemoglobin concentrations in patients receiving inhalation anesthetics (desflurane, enflurane, and isoflurane) have been reported. Recent in vitro studies suggest that dry carbon dioxide absorbents may allow the production
Autor:
T. Philip Malan, R. Joseph Isner, Elizabeth A. Brown, Scott E. Morgan, Burnell R. Brown, Edward J. Frink
Publikováno v:
Anesthesiology. 80:1019-1025
BACKGROUND Sevoflurane, a new inhalational anesthetic, is biotransformed, producing peak plasma inorganic fluoride concentrations that may exceed 50 microM. We evaluated plasma inorganic fluoride concentrations with prolonged (> 9 MAC-h) sevoflurane
Autor:
Edward J. Frink, Scott E. Morgan, T. Philip Malan, R. Joseph Isner, Elizabeth A. Brown, Burnell R. Brown
Publikováno v:
Journal of Clinical Anesthesia. 6:239-242
Study Objectives: To evaluate the decomposition of sevoflurane in soda lime during prolonged sevof lurane anesthesia in humans. To evaluate for evidence of renal or hepatotoxicity as a result of exposure to these sevoflurane degradation compounds. De
Plasma Inorganic Fluoride Levels with Sevoflurane Anesthesia in Morbidly Obese and Nonobese Patients
Publikováno v:
Anesthesia & Analgesia. 76:1333-1337
Administration of several of the inhaled anesthetics result in plasma inorganic fluoride concentrations that are higher in obese compared to nonobese patients. Sevoflurane, a new inhaled anesthetic, is metabolized to inorganic fluoride; however, plas
Publikováno v:
Anesthesiology. 76:85-90
Inhalational anesthetics produce differential effects on hepatic blood flow and oxygenation that may impact hepatocellular function and drug clearance. In this investigation, the effects of sevoflurane on hepatic blood flow and oxygenation were compa
Publikováno v:
Alternatives to Laboratory Animals. 18:191-199
Cultured precision-cut liver slices retain normal liver architecture and physiological biochemical functions. Hartley male guinea-pig liver slices have proven to be a good model for studying the biotransformation and toxicity of halothane. This syste
Publikováno v:
Anesthesiology. 80(1)
BACKGROUND The results of sevoflurane biotransformation (fluoromethyl-1,1,1,3,3,3,-hexafluoro-2-propyl ether) to inorganic fluoride have been examined. However, these investigations have lacked a simplified assay for determining the primary organic m
Autor:
Scott E. Morgan, Edward J. Frink, Ghantous Hn, Fernando J, Malan Tp, Burnell R. Brown, A. J. Gandolfi
Publikováno v:
Anesthesia and analgesia. 74(2)
The biotransformation and plasma inorganic fluoride ion production of sevoflurane (the new volatile anesthetic) during and after surgical anesthesia was studied in 50 ASA I or II surgical patients. Twenty-five additional patients served as controls b
Publikováno v:
Anesthesiology. 73