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pro vyhledávání: '"Scott E. Bowen"'
Acute exposure to abuse-like concentrations of toluene induces inflammation in mouse lungs and brain
Publikováno v:
Journal of applied toxicology : JATREFERENCES. 42(7)
Toluene is an aromatic hydrocarbon commonly abused by young adolescents for its central nervous system depressant effects. Although toluene's pharmacological effects at high concentrations are relatively well-known, few studies have assessed toluene'
Publikováno v:
Neurotoxicology and teratology. 91
Environmental exposure to toxicants is a major health issue and a leading risk factor for premature mortality worldwide, including environmental exposures to volatile organic compounds (VOCs), specifically Benzene, Toluene, Ethylbenzene, and Xylene (
Publikováno v:
Neurotoxicology and teratology. 86
Opioid Use Disorder (OUD) is a global epidemic also affecting women of reproductive age. A standard form of pharmacological treatment for OUD is Opioid Maintenance Therapy (OMT) and buprenorphine has emerged as the preferred treatment for pregnant wo
Autor:
Scott E. Bowen, Silvia L. Cruz
Publikováno v:
Neurotoxicology and Teratology. 87:106999
This paper reviews the scientific evidence generated in the last two decades on the effects and mechanisms of action of most commonly misused inhalants. In the first section, we define what inhalants are, how they are used, and their prevalence world
Publikováno v:
Neuroscience Letters. 647:67-71
The abuse of inhalants like toluene continues to be widespread around the world, especially among children and teenagers. Despite its frequency of misuse, the dynamics between dopamine (DA) and gamma-aminobutyric acid (GABA) in response to toluene ex
Publikováno v:
Environmental Toxicology and Pharmacology. 81:103518
Combined environmental exposures to the volatile organic compounds (VOCs) Benzene, Toluene, Ethylbenzene, and Xylene (BTEX) pose clear risks to public health. Research into these risks is under-studied even as BTEX levels in the atmosphere are predic
Publikováno v:
Toxicology and Applied Pharmacology. 408:115260
Background Intentionally inhaling volatile organic solvent like toluene for its intoxicating effects continues to be a public health concern. While repeated abuse of toluene has deleterious behavioral and health effects, little is known about the act
Publikováno v:
Drug and Alcohol Dependence. 205:107625
The opioid crisis has led to an increased number of pregnant opioid-dependent women receiving opioid-maintenance therapy (e.g. buprenorphine, BUP), but little is known about the consequences of gestational BUP exposure on pregnancy outcomes, maternal
Publikováno v:
Neurotoxicology and teratology. 65
The intentional misuse of volatile solvents like toluene is a persistent public health concern. Limited clinical data suggest that chronic inhalant abusers may experience signs of withdrawal, including anxiety. Behavioral withdrawal from toluene has