Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Scott E Nelson"'
Autor:
Jillian A Bristol, Scott E Nelson, Makoto Ohashi, Alejandro Casco, Mitchell Hayes, Erik A Ranheim, Abigail S Pawelski, Deo R Singh, Daniel J Hodson, Eric C Johannsen, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1012132 (2024)
Epstein-Barr virus (EBV) is an important cause of human lymphomas, including Burkitt lymphoma (BL). EBV+ BLs are driven by Myc translocation and have stringent forms of viral latency that do not express either of the two major EBV oncoproteins, EBNA2
Externí odkaz:
https://doaj.org/article/43ac485e6f8547838097af8a167f2b00
Autor:
Deo R Singh, Scott E Nelson, Abigail S Pawelski, Juan A Cantres-Velez, Alisha S Kansra, Nicholas P Pauly, Jillian A Bristol, Mitchell Hayes, Makoto Ohashi, Alejandro Casco, Denis Lee, Stuart A Fogarty, Paul F Lambert, Eric C Johannsen, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010868 (2022)
Differentiated epithelial cells are an important source of infectious EBV virions in human saliva, and latent Epstein-Barr virus (EBV) infection is strongly associated with the epithelial cell tumor, nasopharyngeal carcinoma (NPC). However, it has be
Externí odkaz:
https://doaj.org/article/c603bab0a33b48b1a46a9dd7f2ea5c12
Autor:
Jillian A Bristol, Joshua Brand, Makoto Ohashi, Mark R Eichelberg, Alejandro Casco, Scott E Nelson, Mitchell Hayes, James C Romero-Masters, Dana C Baiu, Jenny E Gumperz, Eric C Johannsen, Huy Q Dinh, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010453 (2022)
Humans are infected with two types of EBV (Type 1 (T1) and Type 2 (T2)) that differ substantially in their EBNA2 and EBNA 3A/B/C latency proteins and have different phenotypes in B cells. T1 EBV transforms B cells more efficiently than T2 EBV in vitr
Externí odkaz:
https://doaj.org/article/2c768345a77f44aba18e12245a9537ae
Autor:
Nicholas Van Sciver, Makoto Ohashi, Nicholas P Pauly, Jillian A Bristol, Scott E Nelson, Eric C Johannsen, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009783 (2021)
The Epstein-Barr virus (EBV) human herpesvirus is associated with B-cell and epithelial-cell malignancies, and both the latent and lytic forms of viral infection contribute to the development of EBV-associated tumors. Here we show that the Hippo sign
Externí odkaz:
https://doaj.org/article/f47e9a7ea0514e52859e2a560063458c
Autor:
Chunrong Li, James C Romero-Masters, Shane Huebner, Makoto Ohashi, Mitchell Hayes, Jillian A Bristol, Scott E Nelson, Mark R Eichelberg, Nicholas Van Sciver, Erik A Ranheim, Rona S Scott, Eric C Johannsen, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 16, Iss 6, p e1008590 (2020)
EBV transforms B cells in vitro and causes human B-cell lymphomas including classical Hodgkin lymphoma (CHL), Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL). The EBV latency protein, EBNA2, transcriptionally activates the promoters o
Externí odkaz:
https://doaj.org/article/0540b131b0f74025b94cf846f890d69e
Autor:
James C Romero-Masters, Shane M Huebner, Makoto Ohashi, Jillian A Bristol, Bayleigh E Benner, Elizabeth A Barlow, Gail L Turk, Scott E Nelson, Dana C Baiu, Nicholas Van Sciver, Erik A Ranheim, Jenny Gumperz, Nathan M Sherer, Paul J Farrell, Eric C Johannsen, Shannon C Kenney
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008365 (2020)
Humans are infected with two distinct strains (Type 1 (T1) and Type 2 (T2)) of Epstein-Barr virus (EBV) that differ substantially in their EBNA2 and EBNA 3A/B/C latency genes and the ability to transform B cells in vitro. While most T1 EBV strains co
Externí odkaz:
https://doaj.org/article/ec69057eebe34560b5bc126ef97ce47f
Autor:
Deo R. Singh, Scott E. Nelson, Abigail S. Pawelski, Alisha S. Kansra, Stuart A. Fogarty, Jillian A. Bristol, Makoto Ohashi, Eric C. Johannsen, Shannon C. Kenney
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Latent Epstein–Barr virus (EBV) infection promotes undifferentiated nasopharyngeal carcinomas (NPCs) in humans, but the mechanism(s) for this effect has been difficult to study because EBV cannot transform normal epithelial cells in vitro and the E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb62ab0adedf9253cdbe456d6f0eee3b
https://doi.org/10.1073/pnas.2219755120
https://doi.org/10.1073/pnas.2219755120
Autor:
DeannaLee M. Beauvais, Scott E. Nelson, Kristin M. Adams, Noah A. Stueven, Oisun Jung, Alan C. Rapraeger
Publikováno v:
The Journal of biological chemistry. 298(6)
Epidermal growth factor receptor (EGFR) is a causal factor in carcinoma, yet many carcinoma patients are resistant to EGFR inhibitors. Potential insight into this resistance stems from prior work that showed EGFR in normal epithelial cells docks to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd6a4cd213b83310cb27b6d6ef74b9a6
https://pubmed.ncbi.nlm.nih.gov/35569509
https://pubmed.ncbi.nlm.nih.gov/35569509
Autor:
Jillian A. Bristol, Joshua Brand, Makoto Ohashi, Mark R. Eichelberg, Alejandro Casco, Scott E. Nelson, Mitchell Hayes, James C. Romero-Masters, Dana C. Baiu, Jenny E. Gumperz, Eric C. Johannsen, Huy Q. Dinh, Shannon C. Kenney
Publikováno v:
PLoS pathogens. 18(4)
Humans are infected with two types of EBV (Type 1 (T1) and Type 2 (T2)) that differ substantially in their EBNA2 and EBNA 3A/B/C latency proteins and have different phenotypes in B cells. T1 EBV transforms B cells more efficiently than T2 EBV in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8936f5f73319d9c696dac52c5451129
https://pubmed.ncbi.nlm.nih.gov/35472072
https://pubmed.ncbi.nlm.nih.gov/35472072
Autor:
Makoto Ohashi, Nicholas P. Pauly, Jillian A. Bristol, Nicholas Van Sciver, Shannon C. Kenney, Scott E. Nelson, Eric Johannsen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009783 (2021)
PLoS Pathogens
PLoS Pathogens
The Epstein-Barr virus (EBV) human herpesvirus is associated with B-cell and epithelial-cell malignancies, and both the latent and lytic forms of viral infection contribute to the development of EBV-associated tumors. Here we show that the Hippo sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fedde320a29d7b9ff4e4886ab63c1fa
https://doaj.org/article/f47e9a7ea0514e52859e2a560063458c
https://doaj.org/article/f47e9a7ea0514e52859e2a560063458c