Výsledky vyhledávání - "Scott Dieteren"

Akademický článek

Ethyl Pyruvate Reduces Systemic Leukocyte Activation via Caspase-1 and NF-κB After Blunt Chest Trauma and Haemorrhagic Shock

Autor: Scott Dieteren, Niklas Franz, Kernt Köhler, Aleksander Nowak, Sabrina Ehnert, Alexey Surov, Marcus Krüger, Ingo Marzi, Nils Wagner, Borna Relja

Publikováno v: Frontiers in Medicine, Vol 7 (2020)

Background: Blunt chest (thoracic) trauma (TxT) and haemorrhagic shock with subsequent resuscitation (H/R) induce strong systemic and local inflammatory response, which is closely associated with apoptotic cell loss and subsequently impaired organ fu

Externí odkaz: https://doaj.org/article/4b4f09da51ad4e928364f39a2bc23540

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Akademický článek

Ethyl pyruvate ameliorates hepatic injury following blunt chest trauma and hemorrhagic shock by reducing local inflammation, NF-kappaB activation and HMGB1 release.

Autor: Nils Wagner, Scott Dieteren, Niklas Franz, Kernt Köhler, Katharina Mörs, Luka Nicin, Julia Schmidt, Mario Perl, Ingo Marzi, Borna Relja

Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0192171 (2018)

The treatment of patients with multiple trauma including blunt chest/thoracic trauma (TxT) and hemorrhagic shock (H) is still challenging. Numerous studies show detrimental consequences of TxT and HS resulting in strong inflammatory changes, organ in

Externí odkaz: https://doaj.org/article/dccf12f9e6cd45f29e303dc634129ede

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Ethyl pyruvate reduces acute lung damage following trauma and hemorrhagic shock via inhibition of NF-κB and HMGB1

Autor: Mario Perl, Julia Schmidt, Katharina Mörs, Borna Relja, Scott Dieteren, Nils Wagner, Ingo Marzi, Niklas Franz

Publikováno v: Immunobiology. 223:310-318

Objective After blunt thoracic trauma (TxT) and hemorrhagic shock with resuscitation (H/R) intense local inflammatory response and cell loss frequently impair the pulmonary function. Ethyl pyruvate (EP) has been reported to improve the pathophysiolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c52f3774ebbdd97cefaab977cf2e83a
https://doi.org/10.1016/j.imbio.2017.10.037

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Acute Alcohol Binge Deteriorates Metabolic and Respiratory Compensation Capability After Blunt Chest Trauma Followed by Hemorrhagic Shock-A New Research Model

Autor: Ingo Marzi, Niklas Franz, Katharina Mörs, Borna Relja, Scott Dieteren, Nils Wagner, Mario Perl

Publikováno v: Alcoholism: Clinical and Experimental Research. 41:1559-1567

Background and purpose The clinical relevance of blunt (thoracic) chest trauma (TxT) and hemorrhagic shock is indisputable due to the high prevalence of this injury type, as well as its close association with mortality and/or preventable deaths. Furt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b1134d656ea84bc5389311d7f1fae8
https://doi.org/10.1111/acer.13446

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Alcohol‑induced attenuation of post‑traumatic inflammation is not necessarily liver‑protective following trauma/hemorrhage

Autor: Borna Relja, Ingo Marzi, Kernt Köhler, Mario Perl, Niklas Franz, Scott Dieteren, Nils Wagner

Publikováno v: International journal of molecular medicine. 44(3)

Due to their high prevalence, blunt chest trauma (TxT) and hemorrhagic shock have a significant influence on the outcomes of trauma patients, causing severe modulations of the immune system and high mortality rates. Alcohol consumption in trauma pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413be1b1e8224411c2d2c95913b068d2
https://pubmed.ncbi.nlm.nih.gov/31257463

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Alcohol Binge Reduces Systemic Leukocyte Activation and Pulmonary PMN Infiltration After Blunt Chest Trauma and Hemorrhagic Shock

Autor: Borna Relja, Scott Dieteren, Katharina Mörs, Niklas Franz, Ramona Sturm, Nils Wagner, Ingo Marzi, Kernt Köhler, Mario Perl

Publikováno v: Inflammation. 42(2)

Blunt chest (thoracic) trauma (TxT) and hemorrhagic shock (HS)-induced local and systemic inflammation with increased neutrophil activity often result in an impaired organ function. Next to increasing the trauma risk, binge drinking causes anti-infla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00306cc59a58ec61ca025a208799aa21
https://pubmed.ncbi.nlm.nih.gov/30411212

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Ethyl pyruvate ameliorates hepatic injury following blunt chest trauma and hemorrhagic shock by reducing local inflammation, NF-kappaB activation and HMGB1 release

Autor: Julia Schmidt, Nils Wagner, Kernt Köhler, Katharina Mörs, Mario Perl, Borna Relja, Luka Nicin, Niklas Franz, Scott Dieteren, Ingo Marzi

Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0192171 (2018)
PLoS ONE

Background: The treatment of patients with multiple trauma including blunt chest/thoracic trauma (TxT) and hemorrhagic shock (H) is still challenging. Numerous studies show detrimental consequences of TxT and HS resulting in strong inflammatory chang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93043da90557336597385372c14215c2
https://doi.org/10.1371/journal.pone.0192171

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