Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Scott D. Smid"'
Autor:
John Staton Laws III, Scott D. Smid
Publikováno v:
Current Research in Toxicology, Vol 6, Iss , Pp 100144- (2024)
Phytochemicals are often promoted generally as antioxidants and demonstrate variable levels of reactive oxygen species (ROS) sequestration in vitro, which attributes to their neuroprotective bioactivity. Sesquiterpenes from cannabis and essential oil
Externí odkaz:
https://doaj.org/article/aefb67f8c1f94e869803973c003d5e6d
Publikováno v:
Phytomedicine Plus, Vol 1, Iss 4, Pp 100125- (2021)
Background: The polyphenolic phlorotannins derived from brown macroalgae consist of complex polymers of phloroglucinol residues with diverse structures ascribed pleiotropic bioactivity. This study aimed to isolate and purify the phlorotannins from Ec
Externí odkaz:
https://doaj.org/article/9dc40400b88147bc9b1c0521a0309f75
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
Aggregation of α-Synuclein (αS) protein to amyloid fibrils is a neuropathological hallmark of Parkinson's disease (PD). Growing evidence suggests that extracellular αS aggregation plays a pivotal role in neurodegeneration found in PD in addition t
Externí odkaz:
https://doaj.org/article/83b5be88f0f0456d9a407e80b7113400
Autor:
Xinlei Li, Scott D. Smid, Jun Lin, Zhihong Gong, Si Chen, Fangning You, Yan Zhang, Zhilong Hao, Hongzheng Lin, Xiaomin Yu, Xinyi Jin
Publikováno v:
Molecules, Vol 24, Iss 10, p 1926 (2019)
White tea (WT) is one of six tea types originally derived from Fujian Province, China. White tea is known for its health-promoting properties. However, the neuroprotective and anti-aggregatory properties of WT against the hallmark toxic Alzheimer’s
Externí odkaz:
https://doaj.org/article/6798127e3f6a4d9bb8f2246ff1ecd667
Publikováno v:
NeuroToxicology. 90:81-87
Terpenes form a diverse class of naturally occurring chemicals ascribed various biological activities. Cannabis contains over 400 different terpenes of varying chemical complexity which may add to the known biological activities of phytocannabinoids
Publikováno v:
International Journal of Food Science & Technology. 57:4286-4295
Autor:
Dylan T. Marsh, Scott D. Smid
Publikováno v:
Food & Function. 13:11142-11152
The novel flavonoid 2′,3′,4′-trihydroxyflavone (2-D08) reduces ROS generation and inhibits both SN-38- and cytokine-evoked increases in epithelial permeability in vitro.
Autor:
John Staton Laws, Scott D. Smid
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 107
Neurodegenerative diseases and dementia pose a global health challenge in an aging population, exemplified by the increasing incidence and prevalence of its most common form, Alzheimer's disease. Although several approved treatments exist for Alzheim
Publikováno v:
Current Neuropharmacology
In the last few years research into Cannabis and its constituent phytocannabinoids has burgeoned, particularly in the potential application of novel cannabis phytochemicals for the treatment of diverse illnesses related to neurodegeneration and demen
Publikováno v:
ACS Chemical Neuroscience. 11:4469-4477
The association between protein aggregation and neurodegenerative diseases such as Parkinson's disease continues to be well interrogated but poorly elucidated at a mechanistic level. Nevertheless, the formation of amyloid fibrils from the destabiliza